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[acetoxy-(5-nitro-2-furyl)methyl] acetate

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Identification
Molecular formula
C9H9NO7
CAS number
698-82-4
IUPAC name
[acetoxy-(5-nitro-2-furyl)methyl] acetate
State
State

At room temperature, [acetoxy-(5-nitro-2-furyl)methyl] acetate is a solid. It is typically stable under standard conditions and should be handled with proper safety precautions to avoid decomposition and potential exposure risks.

Melting point (Celsius)
72.00
Melting point (Kelvin)
345.15
Boiling point (Celsius)
246.00
Boiling point (Kelvin)
519.15
General information
Molecular weight
257.17g/mol
Molar mass
257.1840g/mol
Density
1.5470g/cm3
Appearence

[Acetoxy-(5-nitro-2-furyl)methyl] acetate is a compound that typically appears as a solid crystalline material. Its coloration can vary and it may appear as a light yellow or tan powder.

Comment on solubility

Solubility of [acetoxy-(5-nitro-2-furyl)methyl] acetate

The solubility of [acetoxy-(5-nitro-2-furyl)methyl] acetate can be influenced by various factors, including temperature, solvent type, and molecular interactions.

Key Points Regarding Solubility:

  • Polarity: The presence of both acetate and nitro groups can significantly affect the polarity of the compound, leading to different solubility patterns in nonpolar vs. polar solvents.
  • Solvent Compatibility: This compound is expected to be more soluble in polar organic solvents such as ethanol and acetone, while showing lower solubility in nonpolar solvents like hexane.
  • Temperature Effects: Typically, increasing the temperature may enhance solubility, as higher temperatures can disrupt intermolecular forces and increase molecular movement.

In summary, the overall solubility of [acetoxy-(5-nitro-2-furyl)methyl] acetate is dictated by its complex functional groups and the nature of the solvent. Understanding these interactions is crucial for applications in various fields, including pharmaceuticals and materials science.

Interesting facts

Interesting Facts about [acetoxy-(5-nitro-2-furyl)methyl] acetate

[acetoxy-(5-nitro-2-furyl)methyl] acetate is a fascinating compound that belongs to the category of nitro derivatives. It has garnered attention in the fields of medicinal and synthetic chemistry due to its unique structure and potential applications. Here are some intriguing points about this compound:

  • Molecular Structure: The presence of both an acetoxy group and a nitro group in its structure can significantly influence the compound's reactivity and biological activities. The 5-nitro-2-furyl ring is known for its capacity to enhance pharmacological properties.
  • Applications: Compounds like [acetoxy-(5-nitro-2-furyl)methyl] acetate are often explored for their potential use in drug development, especially in the creation of anti-cancer agents due to the biological activity exhibited by nitro and furan moieties.
  • Synthetic Pathways: Chemists often study the various synthetic methodologies for obtaining this compound, leading to a better understanding of the reaction mechanisms involved and the conditions required for successful synthesis.
  • Toxicity and Safety: The nitro group in this compound poses considerations regarding toxicity, making it vital for researchers to conduct thorough evaluations in the development and application phases.

In summary, [acetoxy-(5-nitro-2-furyl)methyl] acetate is not just a chemical entity but a subject of interest for its versatile applications and biological implications. As with many nitro-containing compounds, ongoing research could unravel further utilities in pharmacology, impacting future therapeutic strategies.

Synonyms
92-55-7
5-Nitro-2-furaldehyde diacetate
5-Nitro-2-furanmethanediol diacetate
5-Nitrofurfural diacetate
(5-Nitrofuran-2-yl)methylene diacetate
2-(Diacetoxymethyl)-5-nitrofuran
5-Nitrofurfurylidene diacetate
5-Nitrofuraldehyde diacetate
Nitrofuraldehyde diacetate
Methanediol, (5-nitro-2-furanyl)-, diacetate (ester)
5-Nitro-2-furfural diacetate
Nitrofurfural diacetate
5-Nitro-2-furfuraldehyde diacetate
5-Nitro-2-furanmethandiol diacetate
5-Nitro-2-furancarboxaldehyde diacetate
2-FURANMETHANEDIOL, 5-NITRO-, DIACETATE
NSC 5411
MFCD00003244
CCRIS 1191
[acetyloxy-(5-nitrofuran-2-yl)methyl] acetate
5-Nitrofurfurylidene di(acetate)
EINECS 202-166-1
7X0X1KNE3Q
Methanediol, 1-(5-nitro-2-furanyl)-, 1,1-diacetate
5-Nitro-2-furan methandiol diacetate
5-nitro-2-furaldehydediacetate
BRN 0255089
DTXSID5020946
AI3-23602
NSC-5411
(5-nitrofuran-2-yl)methanediyl diacetate
DTXCID50946
EC 202-166-1
5-17-09-00324 (Beilstein Handbook Reference)
NITROFURFURAL DIACETATE [USP-RS]
5-NITRO-2-FURFURYLIDENE DIACETATE
(Acetyloxy)(5-nitro-2-furyl)methyl acetate
NITROFURFURAL DIACETATE (USP-RS)
Methanediol, (5-nitro-2-furanyl)-, diacetate (ester) (8CI,9CI); 2-(Diacetoxymethyl)-5-nitrofuran
(acetyloxy){5-nitro-2-furyl}methyl acetate
UNII-7X0X1KNE3Q
(acetyloxy)(5-nitrofuran-2-yl)methyl acetate
Nifuroxazide Imp. C (EP); Nitrofural Imp. B (EP); Nitrofurfural Diacetate; (5-Nitrofuran-2-yl)methylidene Diacetate; Nifuroxazide Impurity C; Nitrofural Impurity B
5-Nitro-2-furfural Diacetyl Acetal
Nitrofural impurity B
Maybridge1_006444
5-nitro-2-furaldiacetate
CHEMBL402463
SCHEMBL6550567
5-Nitrofurfural Diacetyl Acetal
HMS559M20
HSXKWKJCZNRMJO-UHFFFAOYSA-
NSC5411
2-(Diacetoxymethyl)-5-nitro-furane
Tox21_200727
STK325717
(5-Nitrofuran-2-yl)methylenediacetate
AKOS000121509
DS-6423
FN11774
5-Nitro-2-furaldehyde diacetate, 98%
CAS-92-55-7
NCGC00248811-01
NCGC00258281-01
AC-10064
SY017436
N0218
NS00004286
[acetyloxy-(5-nitro-2-furyl)methyl] acetate
EN300-21060
(Acetyloxy)(5-nitro-2-furyl)methyl acetate #
Methanediol, (5-nitro-2-furanyl)-, diacetate
AH-034/11365345
Nitro-5-furfurylidene diacetate (veterinary usage)
Q5804949
Z104487446
Nitrofural impurity B, European Pharmacopoeia (EP) Reference Standard
Nitrofurfural diacetate, United States Pharmacopeia (USP) Reference Standard
InChI=1/C9H9NO7/c1-5(11)15-9(16-6(2)12)7-3-4-8(17-7)10(13)14/h3-4,9H,1-2H3