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Acetylsalicylaldehyde

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Identification
Molecular formula
C11H12O3
CAS number
693-03-8
IUPAC name
acetyl 3-(2-hydroxyphenyl)propanoate
State
State

At room temperature, Acetylsalicylaldehyde exists as a liquid.

Melting point (Celsius)
-22.50
Melting point (Kelvin)
250.70
Boiling point (Celsius)
278.50
Boiling point (Kelvin)
551.60
General information
Molecular weight
180.19g/mol
Molar mass
180.1920g/mol
Density
1.0210g/cm3
Appearence

Acetylsalicylaldehyde appears as a colorless or slightly yellow liquid. It may also have a characteristic odor.

Comment on solubility

Solubility of Acetyl 3-(2-hydroxyphenyl)propanoate

Acetyl 3-(2-hydroxyphenyl)propanoate, with its complex structure, presents an intriguing profile when it comes to solubility. Understanding the factors influencing the solubility of this compound is essential for its applications in various fields.

  • Polarity: The presence of the hydroxyl group (-OH) contributes to increased polarity, hence enhancing solubility in polar solvents such as water.
  • Hydrogen Bonding: The ability of the hydroxyl group to engage in hydrogen bonding plays a crucial role in solvation, making it more soluble in alcohols and other hydrogen-bonding solvents.
  • Temperature Influence: Like many organic compounds, the solubility of acetyl 3-(2-hydroxyphenyl)propanoate tends to increase with temperature. This can be particularly useful during dissolution processes.
  • pH Sensitivity: The solubility can also vary with pH changes due to the weak acidic nature of the hydroxyl group, which can lead to ionization and increased solubility in basic conditions.

In summary, the solubility of acetyl 3-(2-hydroxyphenyl)propanoate is largely influenced by its molecular structure and the surrounding environment. As noted, "the balance between hydrophilic and hydrophobic characteristics determines the solubility landscape." Therefore, both the solvent choice and conditions must be carefully considered when working with this compound.

Interesting facts

Interesting Facts about Acetyl 3-(2-Hydroxyphenyl)propanoate

Acetyl 3-(2-hydroxyphenyl)propanoate is a fascinating compound with a blend of chemical features that make it a subject of interest in various fields, especially in pharmaceuticals and organic chemistry. Here are some compelling aspects of this compound:

  • Versatile Chemical Structure: The compound's structure includes both an acetyl group and a hydroxyphenyl group, which contribute to its unique reactivity and potential applications in organic synthesis.
  • Potential Biological Activity: Compounds with similar structures to acetyl 3-(2-hydroxyphenyl)propanoate have demonstrated varied biological activities, including anti-inflammatory and antioxidant properties. This opens avenues for further exploration in medicinal chemistry.
  • Applications in Drug Development: The hydroxy group in its structure may enhance the compound's solubility, making it a valuable candidate for drug formulation. Its similarity to common pharmacophores can lead to the development of new therapeutic agents.
  • Synthetic Pathways: Its synthesis often involves well-documented organic reactions, making it accessible for chemists looking to explore new synthetic methodologies or enhance existing ones.
  • Studying Functional Groups: Acetyl 3-(2-hydroxyphenyl)propanoate provides an excellent case study for students learning about the effects of functional groups on compound properties and reactivity.

In conclusion, acetyl 3-(2-hydroxyphenyl)propanoate is more than just a compound; it represents a convergence of chemistry, biology, and medicine. As research continues, it could reveal novel insights and applications that benefit various scientific fields. Keep an eye on this compound for its potential future discoveries!

Synonyms
Acetylmelilotic acid
o-Hydroxyhydrocinnamic acid acetate
Acide acetyl-melilotique [French]
2-(Acetyloxy)benzenepropanoic acid
Benzenepropanoic acid, 2-(acetyloxy)-
BRN 2649964
Acide acetyl-melilotique
HYDROCINNAMIC ACID, o-HYDROXY-, ACETATE
Acide acetyl-o-hydroxyphenyl-3-propionique [French]
DTXSID30937936
AKOS015916604
Acide acetyl-o-hydroxyphenyl-3-propionique
Acetic 3-(2-hydroxyphenyl)propanoic anhydride