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Acridine Orange

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Identification
Molecular formula
C17H20ClN3
CAS number
65-61-2
IUPAC name
acridin-10-ium;chloride
State
State

At room temperature, Acridine Orange typically exists as a solid.

Melting point (Celsius)
268.00
Melting point (Kelvin)
541.15
Boiling point (Celsius)
327.00
Boiling point (Kelvin)
600.15
General information
Molecular weight
301.81g/mol
Molar mass
301.8060g/mol
Density
0.1156g/cm3
Appearence

Acridine Orange hydrochloride is a reddish-orange solid that is soluble in water and ethanol, producing green fluorescence under UV light.

Comment on solubility

Solubility of Acridin-10-ium Chloride

Acridin-10-ium chloride, with its unique structure, presents interesting solubility characteristics. The solubility of this compound can be influenced by various factors such as solvent polarity, temperature, and molecular interactions.

Solubility Characteristics

  • Polar Solvents: Acridin-10-ium chloride generally exhibits high solubility in polar solvents such as water and alcohols. This is due to the ionic nature of the chloride ion, which interacts favorably with polar solvent molecules.
  • Non-Polar Solvents: In contrast, in non-polar solvents like hexane, the solubility of acridin-10-ium chloride is significantly limited. The lack of polar interactions leads to poor solvation.
  • Temperature Dependence: Increasing temperature often enhances solubility for most ionic compounds, including acridin-10-ium chloride, making it more soluble in hot solvents compared to cold.

As a general observation, it is important to note that the larger the *cation* or *anion* in a salt, the more likely it is to exhibit complex solubility patterns. The structure of acridin-10-ium can influence the stability of the dissolved ion pair, affecting the overall solubility in various media.

This highlights that solubility is not merely an intrinsic property of the compound but is profoundly influenced by environmental conditions. As noted, "The solubility of compounds is a dance of interactions between solute, solvent, and temperature."

Interesting facts

Interesting Facts about Acridin-10-ium Chloride

Acridin-10-ium chloride is a fascinating compound that belongs to the acridine family, which is known for its unique ring structure and distinct properties. Here are some intriguing insights:

  • Biological Relevance: Acridin derivatives have shown promise in various biological applications, particularly in antimicrobial and anti-cancer research. They can interact with DNA and RNA, making them valuable in the development of pharmaceutical agents.
  • Fluorescent Properties: This compound exhibits fluorescence, which makes it an essential tool in biochemistry and molecular biology. Researchers often use acridin compounds as fluorescent probes in cellular imaging and diagnostic assays.
  • Stability and Reactions: Acridin-10-ium chloride is known for its stability under various conditions. Its reactions are of great interest in organic chemistry, especially in synthesis applications where it can serve as a key intermediate.
  • Historical Significance: The exploration of acridine structures dates back to the late 19th century. Since then, many acridin derivatives have been investigated, case studies related to their properties and potential applications have evolved significantly.
  • Environmental Applications: Some studies suggest that acridin derivatives may play a role in environmental studies, particularly in the assessment of pollutants, as they can facilitate detection processes for specific toxic substances.

In summary, acridin-10-ium chloride is more than just a chemical compound; it stands at the intersection of chemistry, biology, and environmental science, contributing to our understanding and development of new technologies and medications. As always, the journey of discovery continues!

Synonyms
Acridine, monohydrochloride
acridin-10-ium;chloride
NS00086770