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Acridine-3-amine

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Identification
Molecular formula
C13H10N2
CAS number
5819-97-0
IUPAC name
acridin-3-amine
State
State
At room temperature, Acridine-3-amine is typically a solid, often observed as a crystalline powder. It maintains its integrity well under standard environmental conditions.
Melting point (Celsius)
126.00
Melting point (Kelvin)
399.15
Boiling point (Celsius)
179.00
Boiling point (Kelvin)
452.15
General information
Molecular weight
194.24g/mol
Molar mass
194.2440g/mol
Density
1.3487g/cm3
Appearence
Acridine-3-amine, a derivative of acridine, typically appears as a yellow crystalline solid. Its vibrant color is a distinguishing feature, and the compound may sometimes appear in a duller yellow or pale color depending on its level of purity and any potential impurities present.
Comment on solubility

Solubility of Acridin-3-amine

Acridin-3-amine, with the chemical formula C13H10N2, exhibits a fascinating profile of solubility behaviors influenced by its chemical structure. Understanding the solubility characteristics of this compound can provide insights into its potential applications and limitations in various environments.

Solubility Characteristics

  • Solvent Interactions: Acridin-3-amine is known to be soluble in polar organic solvents such as dimethyl sulfoxide (DMSO) and ethanol, which makes it suitable for certain biochemical applications.
  • Water Solubility: Its solubility in water is relatively low, which can limit its use in aqueous systems.
  • pH Dependency: The solubility may vary with pH changes, being more soluble in acidic conditions due to the protonation of the amino group, enhancing interactions with the solvent.
  • Temperature Influence: An increase in temperature generally enhances solubility, a behavior observed in many organic compounds, including acridin-3-amine.

In summary, while acridin-3-amine shows favorable solubility in selected organic solvents, its limited water solubility indicates a need for tailored methodologies when working with this compound in various applications. As the saying goes, "solubility is the key to accessibility" - understanding the solubility of acridin-3-amine is crucial in unlocking its full potential in research and industry.


Interesting facts

Interesting Facts About Acridin-3-amine

Acridin-3-amine is an intriguing organic compound that belongs to the class of acridine derivatives, which are well-known for their diverse biological activities. Here are some notable aspects of this compound:

  • Biological Relevance: Acridin-3-amine exhibits notable pharmacological properties, making it a subject of interest in medicinal chemistry. Its structure allows for potential applications in the development of therapeutic agents.
  • DNA Intercalation: This compound has the ability to intercalate with DNA, which can influence DNA replication and transcription. This characteristic suggests its potential utility in cancer research and treatment.
  • Antimicrobial Activity: Compounds related to acridin-3-amine have shown promising results against various microbes, indicating that they might serve as a foundation for novel antimicrobial therapies.
  • Research Applications: Acridin-3-amine can be utilized as a fluorescent probe in biochemical assays, assisting researchers in visualizing and tracking biomolecular interactions.

Due to its multifaceted applications and biological importance, acridin-3-amine continues to attract the attention of researchers in fields ranging from pharmaceuticals to biochemistry. As a derivative of acridine, it showcases the vast potential of heterocyclic compounds in scientific innovation.

In the words of a pioneering chemist, "Innovation often lies at the intersection of chemistry and biology, where compounds like acridin-3-amine bridge the gap."

Synonyms
acridin-3-amine
3-Aminoacridine
3-Acridinamine
581-29-3
Acridin-3-ylamine
ACRIDINE, 3-AMINO-
CHEMBL148204
5T83GY5877
CCRIS 2107
3-Aminoakridin [Czech]
3-Aminoakridin
2-Aminoacridine (European)
EINECS 209-461-4
BRN 0143200
UNII-5T83GY5877
3-Amino-acridin
AMINOACRIDINE, 3-
SCHEMBL1229699
DTXSID10206819
ZCA28442
BDBM50419044
NS00033870
Q4634114