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Aminacrine sulfate

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Identification
Molecular formula
C13H15N3·H2SO4
CAS number
xxxxxxx
IUPAC name
acridine-3,6-diamine;sulfuric acid
State
State

At room temperature, aminacrine sulfate is in a solid state, specifically a crystalline powder.

Melting point (Celsius)
228.00
Melting point (Kelvin)
501.00
Boiling point (Celsius)
338.00
Boiling point (Kelvin)
611.00
General information
Molecular weight
393.49g/mol
Molar mass
393.5000g/mol
Density
1.7000g/cm3
Appearence

Aminacrine sulfate appears as a yellow to orange crystalline powder. It is light-sensitive and can fluoresce under ultraviolet light.

Comment on solubility

Solubility of Acridine-3,6-Diamine in Sulfuric Acid

Acridine-3,6-diamine (C13H12N4) behaves interestingly when introduced to sulfuric acid (H2SO4). The nature of this interaction provides insight into the solubility characteristics of the compound:

  • Solubility in Strong Acids: Acridine-3,6-diamine is generally soluble in strong acids like sulfuric acid. This can be attributed to protonation, where the amine groups of the compound accept protons from the acid, enhancing its solubility.
  • Influence of Temperature: Increasing the temperature can further improve the solubility of acridine-3,6-diamine in sulfuric acid, as higher temperatures tend to increase the kinetic energy of the molecules, facilitating dissolution.
  • Concentration Effects: The solubility may also vary with the concentration of sulfuric acid used; typically, a concentrated acid may solubilize acridine-3,6-diamine more effectively than dilute solutions.
  • Insoluble Characteristics in Other Solvents: While highly soluble in acid, acridine-3,6-diamine is much less soluble in common organic solvents, highlighting the role of protonation in enhancing solubility.

This unique solubility in sulfuric acid showcases the importance of molecular structure and environmental conditions, confirming how certain compounds can exhibit varying solubility profiles based on their chemical context. As such, the solubility of acridine-3,6-diamine underscores the fascinating dynamics between acids and organic compounds.

Interesting facts

Interesting Facts about Acridine-3,6-Diamine and Sulfuric Acid

Acridine-3,6-diamine, also known as 3,6-diaminoacridine, is a compound that has garnered attention in the fields of chemistry and biochemistry due to its unique properties and applications. When combined with sulfuric acid, a strong mineral acid, transformative reactions occur that can be quite fascinating for scientists exploring various areas of study.

Key Characteristics and Applications

  • Antimicrobial Activity: Acridine derivatives, including acridine-3,6-diamine, are known for their antimicrobial properties, making them useful in the development of potential therapeutic agents against various pathogens.
  • Fluorescent Properties: This compound can exhibit fluorescence, which lends itself to applications in biochemical assays and cellular imaging, allowing scientists to visualize processes at the molecular level.
  • DNA Interaction: Acridine compounds can intercalate within DNA structures, influencing genetic processes. This feature makes them of particular interest in genetic studies and drug design.
  • Mutagenicity Studies: The study of acridine derivatives has revealed their potential mutagenic effects, prompting further research into their safety and impact on biological organisms.

Why Combine with Sulfuric Acid?

The combination of acridine-3,6-diamine with sulfuric acid creates an environment where protonation occurs, potentially enhancing the reactivity of the acridine molecule. This synthesis could lead to:

  • The formation of sulfonic acids, increasing the solubility and reactivity of the acridine derivatives.
  • A deeper understanding of the acid-base reactions, crucial in organic synthesis and catalysis.

As stated by renowned chemists, "The beauty of chemistry lies in the connections we make between different substances." Studying acridine-3,6-diamine and its interactions with sulfuric acid not only expands our understanding of chemical behavior but also opens doors to innovative applications in medicine, agriculture, and material science.

Synonyms
Proflavine sulfate
553-30-0
Proflavin sulfate
Isoflav
Proflavine sulphate
3,6-Diaminoacridine sulfate
Pancridine
Sanoflavin
Proflavine (sulfate)
Proflavine sulfate [NF]
Neutral proflavine sulphate
3,6-Acridinediamine sulfate
3,6-Acridinediamine sulphate
2,8-Diaminoacridinium sulphate
3,6-Diaminoacridine bisulphate
CCRIS 5162
NSC 1510
NSC-1510
EINECS 209-038-4
3,6-Diaminoacridine sulphate (1:1)
UNII-2961Y60ATP
3,6-Diaminoacridinium monohydrogen sulphate
2961Y60ATP
PROFLAVINE SULFATE [MI]
DTXSID90203821
PROFLAVINE SULFATE [VANDF]
ACRIDINE, 3,6-DIAMINO-, SULFATE (1:1)
DTXCID20126312
acridine-3,6-diamine; sulfuric acid
acridine-3,6-diamine;sulfuric acid
ACRIDINE-3,6-DIAMINE SULFATE
Acridine-3,6-diamine, sulfuric acid
3,6-Diaminoacridine hemisulfate
3, sulfate (1:1)
3,6-Acridinediamine, sulfate (1:1)
Acridine,6-diamino-, sulfate (1:1)
3237-53-4
SCHEMBL380278
CHEMBL1964546
acridine-3,6-diamine hemisulfate
NSC1510
NSC6095
WSFHCKWLECYVBS-UHFFFAOYSA-N
HMS3264C21
Pharmakon1600-01504305
ACRIDINE-3,6-DIAMINESULFATE
NSC-6095
NSC689004
NSC759900
CCG-213924
CS-0260084
NS00080725
EN300-74488
3,6-DIAMINOACRIDINE HEMISULFATE HEMIHYDRATE
Q27254392