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Cobalamin (Vitamin B12)

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Identification
Molecular formula
C63H88CoN14O14P
CAS number
68-19-9
IUPAC name
[amino-[2-[[6-[amino(azaniumylidene)methyl]-1H-benzimidazol-2-yl]-dihydroxy-methyl]-3H-benzimidazol-5-yl]methylene]ammonium
State
State

Vitamin B12 is generally found as a solid at room temperature, often in a crystalline or powdered form suitable for supplement production. It can be dissolved in water, where it forms a red-colored solution, and is stable under normal conditions of storage and handling in a dry state.

Melting point (Celsius)
300.00
Melting point (Kelvin)
573.15
Boiling point (Celsius)
-1.00
Boiling point (Kelvin)
272.15
General information
Molecular weight
1355.37g/mol
Molar mass
1 355.3700g/mol
Density
1.3500g/cm3
Appearence

Cobalamin, commonly known as Vitamin B12, typically appears as a deep red crystalline or powdered substance. The vibrant red color is attributed to its high cobalt content. In its pure form, the compound can exhibit slight iridescence and is usually odorless. Despite its solid form being somewhat granular, it dissolves easily in water, presenting as a clear red solution.

Comment on solubility

Solubility of Amino-[2-[[6-[amino(azaniumylidene)methyl]-1H-benzimidazol-2-yl]-dihydroxy-methyl]-3H-benzimidazol-5-yl]methylene]ammonium

The solubility of the compound C63H88CoN14O14P is influenced by several factors that are conducive to its overall behavior in various solvents. Understanding these factors can provide insights into its applications and interactions in chemical processes.

Key Factors Affecting Solubility:

  • Polarity: The compound contains multiple hydroxyl (-OH) and amino (-NH2) groups, making it relatively polar. This polarity enhances solubility in polar solvents, particularly water.
  • Ionization: Given that this compound is an ammonium salt, it can ionize in aqueous solutions, which typically increases its solubility as the ions disperse throughout the solvent.
  • Hydrogen Bonding: The presence of hydroxyl and amino groups allows for extensive hydrogen bonding with solvents like water, further facilitating solubility.
  • Temperature: Generally, solubility can increase with temperature; hence this compound may exhibit enhanced solubility in hot solvents.

In practice, the solubility of C63H88CoN14O14P can be described as follows:

  1. It is likely to be soluble in water and other polar solvents.
  2. Solubility may vary based on pH levels due to the presence of ionizable functional groups.
  3. Its solubility in nonpolar solvents would be minimal due to the compound's polar character.

In conclusion, the solubility of this compound offers valuable insights into its reactivity and potential applications, making it a compound of interest in various fields.

Interesting facts

Amino-[2-[[6-[amino(azaniumylidene)methyl]-1H-benzimidazol-2-yl]-dihydroxy-methyl]-3H-benzimidazol-5-yl]methylene]ammonium

This fascinating compound, known for its intricate molecular structure, is part of a class of compounds that highlights the synergy between organic chemistry and biochemistry. It features multiple benzimidazole groups, which are recognized for their pharmacological significance and versatility in medicinal chemistry.

Notable Features of the Compound:

  • Benzimidazole Backbone: The presence of two benzimidazole units contributes to its ability to interact with biological systems, making it a point of interest for drug design and development.
  • Metal Coordination: The inclusion of cobalt (Co) in the structure indicates a potential for interesting coordination chemistry, which can lead to unique properties beneficial for catalytic or biomedical applications.
  • Ammonium and Hydroxyl Groups: These functional groups enhance solubility and biological reactivity, potentially improving the compound’s ability to penetrate biological membranes or interact with cellular structures.

Moreover, the complexity of this compound has implications in various research fields, including:

  1. Chemotherapy: Investigations into its antitumor activities due to its structural resemblance to known antineoplastic agents.
  2. Antimicrobial Applications: Exploration of its efficacy against various bacterial strains, leveraging the ability of the azaniumylidene moiety to disrupt microbial cell walls.
  3. Biological Imaging: Potential development as a contrast agent in imaging techniques due to its unique coordination properties.

In summary, the amino-[2-[[6-[amino(azaniumylidene)methyl]-1H-benzimidazol-2-yl]-dihydroxy-methyl]-3H-benzimidazol-5-yl]methylene]ammonium stands as a remarkable example of how complex molecular architectures can pave the way for innovative applications in science and medicine.

Synonyms
bis(5-amidino-2-benzimidazolyl)methane ketone hydrate
BAH
(azaniumyl((2-((6-carbamimidoyl-1H-1,3-benzodiazol-2-yl)dihydroxymethyl)-1H-1,3-benzodiazol-6-yl))methylidene)azanium
[azaniumyl({2-[(6-carbamimidoyl-1H-1,3-benzodiazol-2-yl)dihydroxymethyl]-1H-1,3-benzodiazol-6-yl})methylidene]azanium
[(dihydroxymethanediyl)bis(1h-benzimidazole-2,6-diyl)]bis(aminomethaniminium)
Q27458287