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2-Hydroxy-2-phenylacetic acid

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Identification
Molecular formula
C8H8O3
CAS number
614-48-2
IUPAC name
ammonia;2-hydroxy-2-phenyl-acetic acid
State
State

The compound is in a crystalline solid state at room temperature.

Melting point (Celsius)
98.00
Melting point (Kelvin)
371.15
Boiling point (Celsius)
285.00
Boiling point (Kelvin)
558.15
General information
Molecular weight
152.15g/mol
Molar mass
152.1490g/mol
Density
1.3630g/cm3
Appearence

2-Hydroxy-2-phenylacetic acid appears as a white or off-white crystalline solid. It can also be found in powder form. It is typically odorless or might emit a faint odor characteristic of carboxylic acids.

Comment on solubility

Solubility of Ammonia and 2-Hydroxy-2-phenyl-acetic Acid

Understanding the solubility of chemical compounds is crucial for their applications in various fields. Let's delve into the solubility characteristics of ammonia and 2-hydroxy-2-phenyl-acetic acid.

Ammonia (NH3)

Ammonia is a widely known compound with remarkable solubility properties:

  • High Solubility: Ammonia is highly soluble in water, with a solubility of approximately 700 g/L at 20°C.
  • Temperature Dependence: Its solubility increases with rising temperature, which allows for greater concentrations in warm environments.
  • Polar Nature: The polarity of ammonia molecules facilitates interactions with water, promoting dissolution.

2-Hydroxy-2-phenyl-acetic Acid (C9H10O3)

On the other hand, 2-hydroxy-2-phenyl-acetic acid exhibits unique solubility behavior:

  • Moderate Solubility: This compound is moderately soluble in water due to its hydroxyl group, contributing to hydrogen bonding.
  • Affect of pH: The solubility can be affected by pH levels, as it is more soluble in alkaline conditions where the acidic group may deprotonate.
  • Solvent Compatibility: In organic solvents like ethanol and acetone, 2-hydroxy-2-phenyl-acetic acid shows improved solubility, enhancing its utility in organic synthesis.

In summary, while ammonia exhibits exceptional solubility in water due to its polar attribute, 2-hydroxy-2-phenyl-acetic acid presents moderate solubility influenced by structural properties and environmental conditions. Understanding these solubility profiles is essential for practical applications and further research endeavors.

Interesting facts

Interesting Facts about Ammonia 2-Hydroxy-2-phenyl-acetic Acid

Ammonia 2-hydroxy-2-phenyl-acetic acid, commonly known as a derivative of amino acids, is a fascinating compound due to its unique combination of structural features and applications. Here are some interesting insights:

  • Dual Functionality: This compound exhibits both acidic and basic properties, making it a versatile player in various reactions and processes.
  • Biochemical Importance: As a derivative of phenylalanine, it plays a significant role in metabolic pathways and can influence the synthesis of neurotransmitters.
  • Pharmaceutical Applications: It has potential therapeutic applications, particularly in the development of drugs targeting neurological disorders due to its structural resemblance to biological amino acids.
  • Research Relevance: Scientists are particularly interested in its role in synthetic organic chemistry, where such compounds are utilized for building larger, more complex molecules.
  • Environmental Implications: Ammonia derivatives can have significant effects on the environment, contributing to nutrient cycles and influencing soil health.

In summary, ammonia 2-hydroxy-2-phenyl-acetic acid is not only a compound of interest for its chemical properties but also for its broader implications in the fields of biochemistry, pharmaceuticals, and environmental science. As we delve deeper into its functionalities, we are likely to unveil even more of its secrets, reaffirming its place as a compound worthy of study.

Synonyms
Ammonium mandelate
Mandicid
Amdelate
Ammoket
530-31-4
Ammonium amygdalicum
Ammonium mandelate [USP]
mandelic acid ammonium salt
EINECS 208-475-8
UNII-6PGE18556E
AI3-36574
MANDELIC ACID, AMMONIUM SALT
alpha-Hydroxybenzeneacetic acid monoammonium salt
6PGE18556E
Benzeneacetic acid, alpha-hydroxy-, monoammonium salt
Benzeneacetic acid, alpha-hydroxy-, ammonium salt
Ammonium mandelate (USP)
AMMONIUM MANDELATE [MI]
.ALPHA.-HYDROXYBENZENEACETIC ACID AMMONIUM SALT (1:1)
alpha-Hydroxybenzeneacetic acid ammonium salt (1:1)
Benzeneacetic acid, alpha-hydroxy-, monoammonium salt (9CI)
208-475-8
AMMONIUM M AND ELATE
azane;2-hydroxy-2-phenylacetic acid
Mandelic ammonium salt
Mandelic acid, monoammonium salt
SCHEMBL364164
CHEMBL2105969
DTXSID30967475
AKOS040750465
Hydroxy(phenyl)acetic acid--ammonia (1/1)
Q27265279