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Salicylic Acid

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Identification
Molecular formula
C7H6O3
CAS number
69-72-7
IUPAC name
ammonia;2-hydroxybenzoic acid
State
State

Salicylic acid is generally encountered as a solid at room temperature. It is a dry substance and must be stored carefully to avoid moisture, which can lead to clumping and degradation.

Melting point (Celsius)
158.00
Melting point (Kelvin)
431.15
Boiling point (Celsius)
211.00
Boiling point (Kelvin)
484.15
General information
Molecular weight
138.12g/mol
Molar mass
138.1210g/mol
Density
1.4430g/cm3
Appearence

Salicylic acid appears as a white, crystalline solid that can be powdery. It is typically colorless and can be very fine in texture, often available in a powder or as slender crystalline needles. Salicylic acid is slightly soluble in water but more soluble in organic solvents like ethanol and acetone.

Comment on solubility

Solubility of Ammonia; 2-Hydroxybenzoic Acid

When discussing the solubility of ammonia (NH3) and 2-hydroxybenzoic acid (C7H6O3), it is important to recognize the differing characteristics of these two compounds:

Ammonia (NH3)

- Ammonia is highly soluble in water, with a solubility of about 33% (w/v) at room temperature.
- The molecule can hydrogen bond with water, leading to its **significant mixing** and **interaction** with aqueous environments.
- This high solubility is also utilized for its effectiveness in a variety of applications, including fertilizers and cleaning agents.

2-Hydroxybenzoic Acid (C7H6O3)

- On the other hand, 2-hydroxybenzoic acid, also known as salicylic acid, has moderate solubility in water, approximately 0.2 g/100 mL at room temperature.
- Its solubility is influenced by both the **hydroxyl group (-OH)** and the **carboxylic acid group (-COOH)**, which can interact with water molecules through hydrogen bonding.
- That said, it is more soluble in organic solvents, reflecting a trend where **hydrophobic aromatic systems** can limit solubility in polar solvents like water.

Key Takeaways

  • Ammonia is highly soluble in water, enhancing its applicability in aqueous solutions.
  • 2-Hydroxybenzoic acid has moderate water solubility and exhibits better solubility in organic solvents.

In summary, the solubility profiles of these compounds highlight the impact of molecular structure on solubility behavior. Understanding these properties is essential for practical applications in various chemical contexts.

Interesting facts

Ammonia / 2-Hydroxybenzoic Acid: A Dynamic Duo in Chemistry

Combining the unique properties of ammonia and 2-hydroxybenzoic acid (also known as salicylic acid) offers a fascinating insight into the world of chemical interactions and applications. Here are some interesting facts about these compounds:

Ammonia

  • Essential Nutrient: Ammonia plays a vital role in the nitrogen cycle, acting as a key source of nitrogen for plants.
  • Common Uses: This compound is widely used in fertilizers, cleaning products, and as a refrigerant in industrial processes.
  • Highly Soluble: Ammonia’s water solubility allows it to easily participate in various chemical reactions.

2-Hydroxybenzoic Acid (Salicylic Acid)

  • Medicinal Applications: Salicylic acid is well-known for its use in acne treatment and anti-inflammatory products.
  • Natural Source: It was originally derived from willow bark, which is why it's prominently featured in various herbal remedies.
  • Key Role in Aspirin: It serves as a precursor to the synthesis of aspirin, a common analgesic and anti-inflammatory medication.

When exploring the interaction between these two compounds, one might consider the potential for unique applications. Scholarly quotes often emphasize the importance of synergy in chemistry: "The whole is greater than the sum of its parts." This is particularly true in chemical synthesis, where the combination of ammonia's basicity and the acidic properties of salicylic acid can lead to innovative formulations.

In summary, the significance of both ammonia and 2-hydroxybenzoic acid extends beyond their individual properties, highlighting the intricate connections within the realm of chemistry.

Synonyms
azane;2-hydroxybenzoic acid
ATA fraction 10, ammonium salt
NSC629474
amine salicylate
CHEMBL2105994
AKOS037643205
NSC-629474
AS-10552
CS-0013339
Q4405859
(MW = 138 by mass spectrometry analysis (155 for salt))