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Identification
Molecular formula
C17H23NO4
CAS number
2758-18-1
IUPAC name
azepan-1-yl-(3,4,5-trimethoxyphenyl)methanone
State
State

At room temperature, Azepan-1-yl-(3,4,5-trimethoxyphenyl)methanone is typically found as a solid, specifically as crystalline powder or crystals.

Melting point (Celsius)
136.50
Melting point (Kelvin)
409.65
Boiling point (Celsius)
345.80
Boiling point (Kelvin)
618.95
General information
Molecular weight
281.37g/mol
Molar mass
281.3430g/mol
Density
1.1260g/cm3
Appearence

Azepan-1-yl-(3,4,5-trimethoxyphenyl)methanone is generally a crystalline solid. It has a characteristic appearance of white to off-white crystals or powder.

Comment on solubility

Solubility of azepan-1-yl-(3,4,5-trimethoxyphenyl)methanone

When considering the solubility of azepan-1-yl-(3,4,5-trimethoxyphenyl)methanone, several factors come into play, primarily its chemical structure and the nature of its functional groups. This compound is characterized by the presence of a cyclic amine (azepane) and a trimethoxyphenyl moiety, which significantly influences its solubility properties.

  • Polar vs. Non-Polar: The azepan ring introduces some degree of polarity due to the nitrogen atom, while the trimethoxyphenyl group adds to the hydrophobic character. This combination often results in a compound that is insoluble in water yet shows higher solubility in organic solvents.
  • Temperature Dependence: Like many organic compounds, the solubility of azepan-1-yl-(3,4,5-trimethoxyphenyl)methanone can increase with temperature, making it beneficial to perform solubility tests at varying temperatures for precise assessments.
  • Solvent Compatibility: It is generally soluble in solvents such as ethanol, dichloromethane, and ethyl acetate, which are commonly employed in organic synthesis.

In summary, while azepan-1-yl-(3,4,5-trimethoxyphenyl)methanone is unlikely to dissolve in water due to its complex structure, its solubility in organic solvents makes it an interesting candidate for various applications in chemistry. To quote a common principle in chemistry: "Like dissolves like." Hence, understanding the solubility characteristics of this compound is crucial for its effective utilization in research and development.

Interesting facts

Exploring Azepan-1-yl-(3,4,5-trimethoxyphenyl)methanone

Azepan-1-yl-(3,4,5-trimethoxyphenyl)methanone is a fascinating compound in the realm of organic chemistry, particularly due to its unique structural features and potential applications. Here are some interesting facts about this compound:

  • Structural Complexity: This compound features a seven-membered cyclic amine known as azepane, along with a highly substituted aromatic ring, making its structure quite intricate and biologically relevant.
  • Pharmacological Potential: Compounds that contain both azepane and methoxy-substituted aromatic rings are often studied for their potential therapeutic effects, including neuropharmacological activity. This makes them interesting candidates for drug discovery.
  • Synthetic Versatility: The presence of various functional groups allows for numerous synthetic routes to be explored. This versatility can lead to derivatives with altered properties or enhanced biological activities.
  • Research Interest: The compound, given its unique structure, may serve as a model compound in studies examining structure-activity relationships in medicinal chemistry.
  • Potential Applications: With the growing interest in agents that affect the central nervous system, this compound might find significant applications in developing new treatments for psychiatric conditions.

As you dive deeper into the world of organic compounds, remember that each unique structure tells a story of its own. Understanding these compounds not only enhances our knowledge of chemistry but also opens doors to innovative solutions in medicine and other fields.

Synonyms
BRN 1351915
1H-AZEPINE, HEXAHYDRO-1-(3,4,5-TRIMETHOXYBENZOYL)-
21912-09-4
DTXSID70176327
Hexahydro-1-(3,4,5-trimethoxybenzoyl)-1H-azepine
5-20-04-00041 (Beilstein Handbook Reference)
RefChem:237358
DTXCID3098818
1-(3,4,5-TRIMETHOXYBENZOYL)AZEPANE
CBMicro_015640
azepan-1-yl-(3,4,5-trimethoxyphenyl)methanone
Cambridge id 5257644
Oprea1_115998
STK017608
AKOS000644699
ST052854
BIM-0015640.P001
azepan-1-yl(3,4,5-trimethoxyphenyl)methanone
azaperhydroepinyl 3,4,5-trimethoxyphenyl ketone
AK-968/11180154