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Aziridin-1-yl-[3-[bis(2-chloroethyl)amino]phenyl]methanone

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Identification
Molecular formula
C13H16Cl2N2O
CAS number
77-78-1
IUPAC name
aziridin-1-yl-[3-[bis(2-chloroethyl)amino]phenyl]methanone
State
State

At room temperature, the compound is typically a liquid, although it may crystallize under certain conditions into a solid state.

Melting point (Celsius)
95.00
Melting point (Kelvin)
368.15
Boiling point (Celsius)
390.00
Boiling point (Kelvin)
663.15
General information
Molecular weight
241.12g/mol
Molar mass
241.1240g/mol
Density
1.2200g/cm3
Appearence

The compound typically appears as a colorless to pale yellow liquid with potential darkening over time due to oxidation processes. It may also be presented in its solid form as a crystalline powder.

Comment on solubility

Solubility of Aziridin-1-yl-[3-[bis(2-chloroethyl)amino]phenyl]methanone

The solubility of aziridin-1-yl-[3-[bis(2-chloroethyl)amino]phenyl]methanone in various solvents can significantly affect its biological activity and application in pharmaceuticals. Understanding the solubility characteristics of this compound is crucial for its effective use. Here are some key points to consider:

  • Polar vs. Nonpolar Solvents: The solubility can vary dramatically between polar and nonpolar solvents. Compounds with similar polarities tend to dissolve better in each other due to the principle of "like dissolves like."
  • Temperature Dependence: As a general rule, the solubility of solids usually increases with an increase in temperature. Therefore, heating the solvent may enhance the solubility of this compound.
  • pH Influence: The solubility may also be influenced by the pH of the solution, especially if the compound has ionizable groups. Adjusting the pH could lead to better solubility.
  • Concentration Influence: At high concentrations, solubility can often shift due to saturation, resulting in precipitation. This is particularly important when considering formulations.

In conclusion, exploring the solubility of aziridin-1-yl-[3-[bis(2-chloroethyl)amino]phenyl]methanone in different environments is essential not just for academic understanding but for practical applications in drug formulation and delivery. Proper solubility assessments can facilitate the optimization of therapeutic usage and efficacy.

Interesting facts

Interesting Facts about Aziridin-1-yl-[3-[bis(2-chloroethyl)amino]phenyl]methanone

Aziridin-1-yl-[3-[bis(2-chloroethyl)amino]phenyl]methanone is a fascinating compound that offers a range of intriguing attributes. Here are some key points to consider:

  • Chemical Structure: The unique aziridine ring contributes to the compound's reactivity, making it a notable subject in organic chemistry.
  • Potential Applications: This compound is often studied for its potential use in chemotherapy, particularly due to its structural similarity to other cytotoxic agents. Its interaction with biological systems is a point of significant interest.
  • Mechanism of Action: The presence of the bis(2-chloroethyl)amino group is particularly noteworthy, as it can alkylate DNA and inhibit cell division, presenting a potential mechanism for anti-cancer activity.
  • Research Relevance: Its importance in medicinal chemistry is underscored by research focusing on its toxicity and therapeutic effects, which contribute to understanding how to combat resistant forms of cancer.
  • Safety Concerns: Due to the presence of chlorinated components, handling this compound requires caution. The chloroethyl groups are known for their hazardous properties, highlighting the importance of safety protocols in a laboratory setting.

In the realm of chemical research, compounds like aziridin-1-yl-[3-[bis(2-chloroethyl)amino]phenyl]methanone serve as vital pieces in the quest for novel therapeutic agents. As one scientist noted, "Investigating the properties and effects of such compounds can lead to breakthroughs in cancer treatment and improved patient outcomes." The continued study of this compound will likely yield valuable insights into both its applications and behavior in biological systems.

Synonyms
KETONE, 1-AZIRIDINYL m-(BIS(2-CHLOROETHYL)AMINO)PHENYL
4638-44-2
DTXSID30196824
DTXCID70119315