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Phenyl isocyanate

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Identification
Molecular formula
C6H5NCO
CAS number
103-71-9
IUPAC name
aziridin-1-yl(phenyl)methanone
State
State

Phenyl isocyanate is typically observed as a liquid at room temperature. It is volatile and reacts with water.

Melting point (Celsius)
2.00
Melting point (Kelvin)
275.15
Boiling point (Celsius)
163.00
Boiling point (Kelvin)
436.15
General information
Molecular weight
119.13g/mol
Molar mass
119.1250g/mol
Density
1.0965g/cm3
Appearence

Phenyl isocyanate is a colorless to light yellow liquid. It emits a sharp odor and can darken over time upon exposure to light and moisture.

Comment on solubility

Solubility of Aziridin-1-yl(phenyl)methanone

Aziridin-1-yl(phenyl)methanone, with its intriguing structure, displays unique solubility characteristics that can vary significantly depending on the solvent used. Understanding its solubility is essential for various applications, including synthesis and formulation. Here are some key points regarding its solubility:

  • Polar Solvents: This compound tends to have limited solubility in highly polar solvents such as water. This is primarily due to the presence of the aziridine moiety, which may not interact favorably with polar molecules.
  • Non-Polar Solvents: In contrast, aziridin-1-yl(phenyl)methanone shows improved solubility in non-polar solvents like hexane or toluene. The hydrophobic phenyl group enhances its solubility in such media.
  • Medium Polarity Solvents: Solvents such as ethanol or acetone can offer moderate solvating power, allowing for some degree of solubility.
  • Factors Influencing Solubility: The solubility of aziridin-1-yl(phenyl)methanone can also be influenced by temperature and the presence of other solutes. For example, increasing the temperature typically increases solubility.

To summarize, aziridin-1-yl(phenyl)methanone has variable solubility based on solvent polarity, with noticeable preferential solubility in non-polar environments. Understanding these solubility dynamics is crucial for its effective use in chemical processes.

Interesting facts

Interesting Facts About Aziridin-1-yl(phenyl)methanone

Aziridin-1-yl(phenyl)methanone is a fascinating compound known for its unique structure and reactivity. Here are some intriguing aspects of this chemical:

  • Aziridine Ring: The compound features a three-membered aziridine ring, which is a cyclic amine. This ring is known for its strain due to the angular arrangement of its atoms, making it highly reactive in chemical reactions.
  • Diverse Applications: Aziridin-1-yl(phenyl)methanone has been studied for its potential applications in medicinal chemistry, particularly in the development of new pharmaceuticals. Compounds containing aziridine structures are often evaluated for their efficacy as anti-cancer agents.
  • Building Block: This compound serves as a valuable building block in organic synthesis, allowing chemists to create more complex molecules through various reaction pathways. Its reactive nature can facilitate the formation of larger and more intricate molecular structures.
  • Unique Reactivity: The electrophilic character of the carbonyl group in this compound enhances its reactivity, promoting interactions with nucleophiles. This feature is particularly useful in organic synthesis, enabling chemists to design specific reactions.
  • Research in Focus: There is ongoing research into the properties and behaviors of aziridinyl compounds, including their mechanisms of action and interactions in biological systems, which could lead to new discoveries in the field of drug development.

In summary, aziridin-1-yl(phenyl)methanone is more than just a compound; it represents a valuable resource in the arsenal of a chemist, opening doors to innovation in synthetic methodologies and potential medical applications. As scientists continue to explore its properties, the future may unlock even greater potentials.

Synonyms
1-Benzoylaziridine
7646-66-4
N-Benzoylaziridine
aziridin-1-yl(phenyl)methanone
AZIRIDINE, 1-BENZOYL-
N-Benzoylethylenimine
1-Benzoylethylenimine
AI3-50744
NSC-3374
NSC-219873
WLN: T3NTJ AVR
Benzoylethylenimide
NSC 3374
EINECS 231-586-8
NSC 219873
BRN 0116575
aziridin-1-yl-phenylmethanone
benzoylaziridine
1-(benzoyl)aziridine
ARY8E9KP69
SCHEMBL252026
DTXSID10227261
NSC3374
NSC219873
AKOS006240810
DB-259395
NS00037793