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Aziridine-1-carboxamide

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Identification
Molecular formula
C2H4N2O
CAS number
291-62-1
IUPAC name
aziridine-1-carboxamide
State
State

At room temperature, aziridine-1-carboxamide is typically found as a crystalline solid. It is stable under normal conditions but should be handled with care due to its potentially hazardous nature.

Melting point (Celsius)
82.50
Melting point (Kelvin)
355.65
Boiling point (Celsius)
235.00
Boiling point (Kelvin)
508.15
General information
Molecular weight
85.10g/mol
Molar mass
85.0970g/mol
Density
1.3100g/cm3
Appearence

Aziridine-1-carboxamide is typically a colorless crystalline solid that may have a faint ammoniacal odor. It appears as a fine powder or crystalline solid depending on the purity and specific form of the compound used.

Comment on solubility

Solubility of Aziridine-1-carboxamide

Aziridine-1-carboxamide, with the chemical formula C3H6N2O, exhibits interesting solubility characteristics that are essential in various applications. Understanding the solubility of this compound can be broken down into several key points:

  • Polarity: Aziridine-1-carboxamide is a polar compound due to the presence of the amide functional group, which can form hydrogen bonds. This polarity enhances its solubility in polar solvents such as water.
  • Solvent Compatibility: It is generally highly soluble in aqueous solutions, making it an excellent candidate for biological and chemical processes requiring water as a solvent.
  • Temperature Dependence: The solubility of aziridine-1-carboxamide may vary with temperature, often increasing at elevated temperatures. This is a common trend observed in many organic compounds.
  • Concentration Impacts: At higher concentrations, the solubility behavior can change, leading to potential precipitation if the saturation point is exceeded.

In summary, the solubility of aziridine-1-carboxamide is influenced by its structural features and the nature of the solvent, making it a compound of interest not only in solution chemistry but also in various practical applications.

Interesting facts

Interesting Facts about Aziridine-1-Carboxamide

Aziridine-1-carboxamide is a fascinating compound that has garnered attention for its unique structure and potential applications. Here are some interesting points about this intriguing compound:

  • Structure: Aziridine-1-carboxamide features a three-membered nitrogen-containing ring, known as an aziridine, which is notable for its strain and reactivity due to the small ring size.
  • Reactivity: The presence of both a carboxamide functional group and an aziridine ring makes this compound an interesting subject for chemists looking to understand strained ring chemistry and nucleophilic substitution reactions.
  • Biological Activity: Aziridine derivatives, including aziridine-1-carboxamide, have been studied for their potential biological properties, including antimicrobial and anticancer activities. As noted in some studies, "the ability of aziridine derivatives to interact with biological targets places them at the forefront of medicinal chemistry."
  • Synthesis: The synthesis of aziridine-1-carboxamide can involve various methods, often leveraging the reactivity of carboxylic acids and amines in the presence of appropriate catalysts, making it a valuable compound in synthetic chemistry.
  • Applications: Beyond its medicinal potential, aziridine-1-carboxamide may also serve as an intermediate in the synthesis of more complex molecules, making it a useful building block in organic synthesis.

As research continues, the versatile nature of aziridine-1-carboxamide is likely to yield new discoveries and applications in the fields of pharmaceuticals and organic chemistry. Its unique properties and reactivity make it a compound worth studying and understanding in depth.

Synonyms
Aziridinyl urea
N-Ethylene urea
1-AZIRIDINECARBOXAMIDE
1,1-Ethyleneurea
BRN 0106940
3715-65-9
DTXSID80190635
5-20-01-00045 (Beilstein Handbook Reference)
DTXCID20113126
N-carbamoylaziridine
AKOS006337916