Skip to main content

Hydroxyquinol

ADVERTISEMENT
Identification
Molecular formula
C6H6O3
CAS number
533-73-3
IUPAC name
benzene-1,2,4-triol
State
State

At room temperature, Hydroxyquinol is in a solid state. It forms crystalline structures that maintain stability under normal conditions.

Melting point (Celsius)
140.00
Melting point (Kelvin)
413.00
Boiling point (Celsius)
309.00
Boiling point (Kelvin)
582.00
General information
Molecular weight
126.11g/mol
Molar mass
126.1110g/mol
Density
1.5720g/cm3
Appearence

Hydroxyquinol appears as a crystalline solid. It is typically white, but it can appear slightly off-white due to impurities or exposure to air and light, which can lead to slight discoloration.

Comment on solubility

Solubility of Benzene-1,2,4-triol

Benzene-1,2,4-triol, also known as pyrogallol, is a compound that exhibits some interesting solubility properties. Its solubility can be influenced by various factors, including polarity and functional groups present in the molecule.

Solubility Characteristics

  • Polar and Nonpolar Solvent Interaction: Due to the presence of hydroxyl groups (-OH), benzene-1,2,4-triol is generally more soluble in polar solvents like water.
  • Water Solubility: It has a relatively high solubility in water, which can be attributed to hydrogen bonding between the hydroxyl groups of pyrogallol and water molecules.
  • Organic Solvent Solubility: In nonpolar solvents, the solubility is considerably lower due to the hydrophobic nature of the benzene ring.

In summary, "the solubility of benzene-1,2,4-triol is predominantly in polar environments," making it a compound of interest in various chemical applications and formulations where water solubility is beneficial. Keep in mind that temperature and pH can also have an effect on its solubility characteristics.

Interesting facts

Interesting Facts about Benzene-1,2,4-triol

Benzene-1,2,4-triol, also known as resorcinol, is a fascinating compound that has garnered attention in both industrial applications and research. Here are some notable facts:

  • Structure and Isomerism: Benzene-1,2,4-triol exhibits a unique structure characterized by the presence of three hydroxyl groups attached to the benzene ring at the 1, 2, and 4 positions. Its structural arrangement leads to interesting isomeric relationships with other phenolic compounds.
  • Biological Significance: This compound plays a crucial role in various biological processes. Resorcinol is studied for its potential therapeutic effects, particularly in dermatology, where it serves as an antiseptic and astringent in ointments and formulations.
  • Industrial Applications: Benzene-1,2,4-triol is an important intermediate in the synthesis of dyes, plastics, and pharmaceuticals. Its chemical reactivity makes it a valuable precursor in organic synthesis.
  • Natural Occurrence: Resorcinol can be found in several natural sources, including plants, where it contributes to the production of flavonoids and tannins, playing a role in plant defense mechanisms.
  • Safety and Toxicology: While benzene-1,2,4-triol is generally regarded as safe for topical applications, exposure can lead to irritation. It is essential to handle it with care in laboratory settings and industrial applications.
  • Research Insights: Recent studies have revealed its potential in anti-cancer research, with ongoing investigations exploring its ability to inhibit certain cancer cell pathways. This opens up discussions about its use as a scaffold for drug development.

In summary, benzene-1,2,4-triol is more than just a chemical compound; it is a multifaceted substance with substantial relevance in both chemistry and biology. Its diverse applications, natural occurrence, and potential benefits in health underline the significance of understanding such organic compounds.

Synonyms
1,2,4-BENZENETRIOL
Benzene-1,2,4-triol
1,2,4-Trihydroxybenzene
Hydroxyhydroquinone
Hydroxyquinol
Oxyhydroquinone
2,5-Dihydroxyphenol
Oxyhydrochinon
Hydroquinone, hydroxy-
1,3,4-Trihydroxybenzene
1,3,4-Benzenetriol
Oxyhydrochinon [German]
NSC 2818
CCRIS 2987
EINECS 208-575-1
UNII-173O8B04RD
BRN 2042863
CHEBI:16971
IMEXINE OAM
AI3-19361
NSC-2818
2-Hydroxy-1,4-hydroquinone
2-Hydroxy-p-benzohydroquinone
DTXSID3040930
4-06-00-07338 (Beilstein Handbook Reference)
1,2,4-BENZENETRIOL [MI]
DTXCID1020930
1,2,4-TRIHYDROXYBENZENE [INCI]
ggnqrnbdzqjccn-uhfffaoysa-n
inchi=1/c6h6o3/c7-4-1-2-5(8)6(9)3-4/h1-3,7-9
533-73-3
4-Hydroxycatechol
MFCD00002198
173O8B04RD
1,4-Benzenetriol
Benzene-1,4-triol
1,4-Trihydroxybenzene
monohydroxy hydroquinone
WLN: QR BQ DQ
bmse000831
1,2,4-trihydroxy benzene
SCHEMBL33527
CHEMBL3092389
NSC2818
1,2,4-Benzenetriol technical grade
c0264
AKOS015889832
CS-W011167
DS-8585
FB18185
HY-W010451
AC-12373
SY004215
DB-018727
1,2,4-Benzenetriol, ReagentPlus(R), 99%
H0249
NS00001197
C02814
EN300-141499
Q903332
1,2,4-Benzenetriol, Vetec(TM) reagent grade, 98%
Z1255438414
1,2,4-Trihydroxybenzene;Hydroxyhydroquinone;Hydroxyhydroquinone
HQN