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Resorcinol

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Identification
Molecular formula
C6H6O2
CAS number
108-46-3
IUPAC name
benzene-1,3-diol
State
State

At room temperature, resorcinol is typically in a solid state. Its crystalline nature grants it stability under standard conditions of pressure and temperature.

Melting point (Celsius)
110.00
Melting point (Kelvin)
383.15
Boiling point (Celsius)
281.00
Boiling point (Kelvin)
554.15
General information
Molecular weight
110.11g/mol
Molar mass
110.1110g/mol
Density
1.2830g/cm3
Appearence

Resorcinol appears as a white to light pink crystalline solid. It can also sometimes appear as needles or flakes. It is soluble in water, alcohol, and ether, and has a faintly sweet odor when pure.

Comment on solubility

Solubility of Benzene-1,3-diol (C6H6O2)

Benzene-1,3-diol, also known as resorcinol, exhibits an interesting solubility profile that is influenced by its unique structure. The compound contains both aromatic and hydroxyl functional groups, which play a crucial role in its solubility characteristics.

Solubility in Water

Resorcinol is moderately soluble in water due to the presence of the hydroxyl (-OH) groups, which can form hydrogen bonds with water molecules. This solubility allows for the following properties:

  • Hydrogen Bonding: The -OH groups interact favorably with polar water molecules.
  • Limitations: While it is soluble, its solubility is not unlimited; as the temperature increases, solubility can also improve.

Solubility in Organic Solvents

Conversely, benzene-1,3-diol is also soluble in various organic solvents such as alcohols and ethers, which can be attributed to:

  • Aromatic Nature: The benzene ring provides a non-polar character that enhances solubility in non-polar solvents.
  • Compatibility: Compatible with solvents that can engage in van der Waals interactions.

In conclusion, resorcinol exhibits a dual solubility nature that allows it to be useful in both aqueous and organic environments. Understanding its solubility can help in leveraging its properties for various applications in chemical formulations.

Interesting facts

Interesting Facts about Benzene-1,3-diol

Benzene-1,3-diol, commonly known as resorcinol, is a fascinating compound that plays a significant role in various industrial and pharmaceutical applications. Here are some key insights:

  • Chemical Structure: Resorcinol is a dihydroxy benzene derivative, featuring two hydroxyl (–OH) groups attached to the benzene ring at the 1 and 3 positions. This unique arrangement influences its chemical reactivity and properties.
  • Applications: It is widely used in the production of resins, adhesives, and dyes. In the pharmaceutical industry, resorcinol serves as an active ingredient in topical medications for skin ailments such as acne and eczema.
  • Antiseptic Qualities: Due to its antimicrobial properties, resorcinol is often utilized as an antiseptic and antifungal agent. It is effective in treating minor skin irritations and infections.
  • Historical Significance: The compound has a rich history dating back to its discovery in the 19th century. It has been employed in various scientific studies and industrial processes, showcasing its versatility and importance to chemists.
  • Safety Considerations: While resorcinol has many beneficial uses, it is essential to handle it with care as it can be irritating to the skin and eyes. Proper safety protocols should always be followed in laboratory and industrial settings.

In summary, benzene-1,3-diol exemplifies the intersection of chemistry and practical application. Its unique structure and properties make it an invaluable compound in both industrial manufacturing and healthcare.

Synonyms
resorcinol
108-46-3
benzene-1,3-diol
1,3-Benzenediol
1,3-Dihydroxybenzene
Resorcin
m-Hydroquinone
m-Hydroxyphenol
m-Dihydroxybenzene
3-Hydroxyphenol
Resorcine
m-Benzenediol
m-Dioxybenzene
Dihydroxybenzol
Resorzin
Developer O
Developer R
Developer RS
Fouramine RS
Fourrine EW
Pelagol RS
Pelagol Grey RS
Resorcinolum
Fourrine 79
Nako TGG
Durafur developer G
C.I. Oxidation Base 31
Phenol, m-hydroxy-
C.I. Developer 4
Benzene, m-dihydroxy-
Rcra waste number U201
Benzene, 1,3-dihydroxy-
3-Hydroxycyclohexadien-1-one
FEMA No. 3589
Acnomel
Resorcinum
Rezamid
Sulforcin
Resorcinol (USP)
NCI-C05970
NSC 1571
C.I. 76505
CCRIS 4052
HSDB 722
UNII-YUL4LO94HK
YUL4LO94HK
RCRA waste no. U201
NSC-1571
EINECS 203-585-2
.alpha.-Resorcinol
Resorcin (JAN)
Resorcin (TN)
Resorcinol [USP]
EPA Pesticide Chemical Code 071401
BRN 0906905
1,3-Dihydroxybenzol
DTXSID2021238
CHEBI:27810
AI3-03996
MFCD00002269
CHEMBL24147
DTXCID601238
C.I.-76505
EC 203-585-2
4-06-00-05658 (Beilstein Handbook Reference)
Resorcinol [UN2876] [Poison]
NCGC00091501-01
RESORCIN [JAN]
BENZENE,1,3-DIHYDROXY RESORCINOL
RESORCINOL (IARC)
RESORCINOL [IARC]
RESORCINOL (MART.)
RESORCINOL [MART.]
RESORCINOL (USP-RS)
RESORCINOL [USP-RS]
RCO
Caswell No. 723
RESORCINOL (EP MONOGRAPH)
RESORCINOL [EP MONOGRAPH]
RESORCINOL (USP MONOGRAPH)
RESORCINOL [USP MONOGRAPH]
Rezorsine
m-phenylenediol
Reso
Rodol RS
203-585-2
CAS-108-46-3
FLUORESCEIN IMPURITY A (EP IMPURITY)
FLUORESCEIN IMPURITY A [EP IMPURITY]
HEXYLRESORCINOL IMPURITY B (EP IMPURITY)
HEXYLRESORCINOL IMPURITY B [EP IMPURITY]
UN2876
Remazol
RS 11H
RS 11L
m-hydroxy-phenol
3-hydroxy-phenol
Resorcinol, ACS
3aqt
3-Hydroxy phenol
Resorcinol, 8CI
benzen-1,3-diol
Resorcinol, Reagent
1,3-benzene diol
Resorcine, technical
1,3-dihyroxybenzene
Acnomel (Salt/Mix)
Eskamel (Salt/Mix)
Rezamid (Salt/Mix)
phenol derivative, 3
Benzene,3-dihydroxy-
NAKO-TGG
Sulforcin (Salt/Mix)
1,3-dihydroxy-benzene
Spectrum_000173
M-Dihydroxybenzene,(S)
RESORCINOL [MI]
Spectrum2_001310
Spectrum3_000895
Spectrum4_000990
Spectrum5_001152
RESORCINOL [FHFI]
RESORCINOL [HSDB]
RESORCINUM [HPUS]
WLN: QR CQ
DURAFOR DEVELOPER G
RESORCINOL [VANDF]
bmse000415
1,3-Dihydroxybenzene, XII
NCIOpen2_003867
RESORCINOL [WHO-DD]
SCHEMBL15515
KBioGR_001399
KBioSS_000653
Resorcinol, >=98%, FG
Resorcinol, Flake, Technical
Resorcinol, LR, >=99%
BIDD:ER0285
DivK1c_000041
SPECTRUM1500527
SPBio_001379
Resorcinol, BioXtra, >=99%
BDBM26189
FEMA 3589
HMS500C03
KBio1_000041
KBio2_000653
KBio2_003221
KBio2_005789
KBio3_001810
Resorcinol, reagent grade, 98%
NSC1571
4e49
NINDS_000041
HMS1920P06
HMS2092G07
Pharmakon1600-01500527
1,3-Dihydroxybenzene (Resorcinol)
Resorcinol (1,3-Dihydroxybenzene)
HY-B0907
Resorcinol, ReagentPlus(R), 99%
Tox21_111140
Tox21_202417
Tox21_300140
CCG-39248
MSK000085
NSC757310
Resorcinol 10 microg/mL in Methanol
Resorcinol, Crystalline Powder, USP
STL185604
AKOS000119813
Resorcinol, ACS reagent, >=99.0%
Tox21_111140_1
DB11085
FR07869
NSC-757310
UN 2876
IDI1_000041
NCGC00091501-02
NCGC00091501-03
NCGC00091501-04
NCGC00091501-05
NCGC00091501-06
NCGC00253918-01
NCGC00259966-01
Resorcinol, p.a., 99.0-100.5%
AC-14363
BP-21158
DA-67166
LS-13122
Resorcinol, SAJ first grade, >=98.0%
SBI-0051505.P003
Resorcinol, JIS special grade, >=99.0%
NS00007013
R0008
S4579
3-Hydroxycyclohexadien-1-one;3-Hydroxyphenol
EN300-19643
1,3-BENZENEDIOL; 1,3-DIHYDROXYBENZENE
C01751
D00133
AB00052085_03
A801880
Q408865
SR-05000002092
FLUORESCEIN SODIUM IMPURITY A [EP IMPURITY]
SR-05000002092-1
BRD-K74190368-001-02-7
BRD-K74190368-001-04-3
F1908-0097
Resorcinol, certified reference material, TraceCERT(R)
Z104474576
Resorcinol, European Pharmacopoeia (EP) Reference Standard
Resorcinol, United States Pharmacopeia (USP) Reference Standard
InChI=1/C6H6O2/c7-5-2-1-3-6(8)4-5/h1-4,7-8
Hymecromone impurity A, European Pharmacopoeia (EP) Reference Standard
Resorcinol, Pharmaceutical Secondary Standard; Certified Reference Material