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Benzidine dihydrochloride

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Identification
Molecular formula
C12H12N2 ; 2HCl
CAS number
531-85-1
IUPAC name
benzidine;dihydrochloride
State
State

At room temperature, benzidine dihydrochloride is typically a solid. It exists as a crystalline powder which is stable under normal conditions but should be stored in a cool, dry place to maintain its stability and prevent degradation.

Melting point (Celsius)
228.00
Melting point (Kelvin)
501.15
Boiling point (Celsius)
384.00
Boiling point (Kelvin)
657.15
General information
Molecular weight
253.15g/mol
Molar mass
253.1480g/mol
Density
1.1600g/cm3
Appearence

Benzidine dihydrochloride typically appears as beige or reddish-brown crystals or powder. It may also be seen as yellow or tan crystals depending on its specific purity and form. The compound's crystal form is highly dependent on environmental factors such as humidity and temperature.

Comment on solubility

Solubility of Benzidine Dihydrochloride

Benzidine dihydrochloride, a salt formed from benzidine and hydrochloric acid, demonstrates particular solubility characteristics that are noteworthy:

  • Water Solubility: Benzidine dihydrochloride is known to be soluble in water due to its ionic nature. The presence of chloride ions allows it to disperse effectively in aqueous solutions.
  • Solvent Interaction: It is less soluble in organic solvents, which highlights its preference for polar environments. This is important for applications that require aqueous processes.
  • Temperature Effects: Solubility may increase with temperature, which is common for ionic compounds.

As a general observation, the solubility of ionic compounds like benzidine dihydrochloride is influenced by the nature of the solvent and temperature. Therefore, when considering its use in various chemical reactions or applications, it is crucial to account for these factors to optimize performance and outcomes!

Interesting facts

Interesting Facts about Benzidine Dihydrochloride

Benzidine dihydrochloride is a fascinating organic compound that has significant importance in the field of chemistry and various applications. Here are some key points to consider:

  • Chemical Structure: Benzidine itself is a biphenyl compound, consisting of two aniline groups. When it forms the dihydrochloride salt, it indicates the presence of two hydrochloric acid molecules linked to it, making it more soluble in water.
  • Historical Background: This compound was first synthesized in the 19th century and was extensively studied due to its role as a chemical intermediate in the production of dyes, particularly azo dyes. These dyes revolutionized the textile industry.
  • Biological Activity: Interestingly, benzidine is known for its controversial history related to carcinogenicity. It has been classified as a potential human carcinogen, leading to strict regulations regarding its use in industrial applications.
  • Applications: Despite its risks, benzidine dihydrochloride is utilized in various applications, such as:
    • Production of colorants and pigments
    • Synthesis of advanced polymers
    • Research on biochemical markers
  • Safety Precautions: When handling this compound, it's crucial to observe proper safety protocols, as exposure can pose health risks. Safety gear such as gloves, masks, and goggles should always be worn.
  • Research Interest: Due to its properties and biological implications, it continues to be a topic of research to understand its mechanisms of action and to develop safer alternatives.

In conclusion, benzidine dihydrochloride represents a compound steeped in both historical significance and contemporary research challenges. As we continue to delve into its chemistry, understanding its impacts—both positive and negative—remains essential for chemists and industry professionals alike.

Synonyms
BENZIDINE DIHYDROCHLORIDE
531-85-1
Benzidine HCl
CCRIS 1412
Dihidrocloruro de benzidina
UNII-LVU06XHC39
NSC 3500
EINECS 208-519-6
LVU06XHC39
Dihidrocloruro de benzidina [Spanish]
(1,1'-Biphenyl)-4,4'-diamine, dihydrochloride
[1,1'-Biphenyl]-4,4'-diamine, dihydrochloride
DTXSID7020138
DTXCID10138
NSC-3500
(1,1'-Biphenyl)-4,4'-diamine, hydrochloride (1:2)
Benzidine, dihydrochloride
[1,1'-Biphenyl]-4,4'-diamine, hydrochloride (1:2)
(1,1'Biphenyl)4,4'diamine, dihydrochloride
208-519-6
Benzidine.2HCl
4-(4-aminophenyl)aniline;dihydrochloride
4,4'-Diaminobiphenyl dihydrochloride
biphenyl-4,4'-diamine dihydrochloride
benzidinedihydrochloride
Biphenyl-4,4'-diamine Dihydrochloride (Benzidine Dihydrochloride)
Biphenyl-4,4'-diamine Dihydrochloride; Phenylbutazone Imp. E (EP) as Dihydrochloride; Benzidine Dihydrochloride; Phenylbutazone Impurity E as Dihydrochloride
SCHEMBL453681
CHEMBL3184470
Tox21_202584
MFCD00040389
AKOS005267242
NCGC00260133-01
CAS-531-85-1
FB147203
NS00093478
Benzidine dihydrochloride, >=99% (titration)
E83125
Q26841199
Benzidine dihydrochloride, for experimental carcinogenesis, >=99.0%