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8-Hydroxybenzo[a]pyrene

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Identification
Molecular formula
C20H12O
CAS number
478-65-9
IUPAC name
benzo[a]pyren-8-ol
State
State

At room temperature, 8-Hydroxybenzo[a]pyrene is a solid, maintaining stability under standard conditions. It is generally handled and stored in its solid state.

Melting point (Celsius)
181.00
Melting point (Kelvin)
454.15
Boiling point (Celsius)
524.00
Boiling point (Kelvin)
797.15
General information
Molecular weight
268.31g/mol
Molar mass
268.3130g/mol
Density
1.3510g/cm3
Appearence

8-Hydroxybenzo[a]pyrene typically appears as a crystalline solid. It is often presented as a yellow-tinted powder that is finely textured, having a clear, crystalline structure that occasionally shows fluorescent properties under certain types of lighting.

Comment on solubility

Solubility of Benzo[a]pyren-8-ol

Benzo[a]pyren-8-ol, a hydroxylated polycyclic aromatic hydrocarbon, exhibits intriguing solubility characteristics. Its solubility can be influenced by various factors such as polarity, temperature, and the presence of other solvents.

Generally, the solubility of benzo[a]pyren-8-ol is characterized by:

  • Low water solubility: This compound is primarily hydrophobic, making it poorly soluble in water.
  • Higher solubility in organic solvents: It tends to dissolve better in organic solvents like methanol, ethanol, and acetone due to its non-polar nature.
  • Temperature dependence: As with many organic compounds, solubility may increase with rising temperature, making it essential to consider thermal conditions.
  • pH sensitivity: The solubility may also vary with pH levels, potentially impacting its behavior in various environments.

In summary, while benzo[a]pyren-8-ol is not readily soluble in water, it demonstrates a greater affinity for organic solvents, which is a common trait among similar organic compounds. As noted, understanding the solubility patterns is crucial for practical applications and studies regarding its environmental behavior and toxicology.

Interesting facts

Benzo[a]pyren-8-ol: An Intriguing Compound

Benzo[a]pyren-8-ol is a fascinating polycyclic aromatic hydrocarbon that has captured the interest of scientists across various fields, particularly in environmental chemistry and toxicology. As a derivative of benzo[a]pyrene, which is known for its carcinogenic properties, this compound presents an interesting study of structure-activity relationships.

Key Features

  • Cancer Research: Benzo[a]pyren-8-ol has been studied extensively for its role as a metabolite of benzo[a]pyrene, making it a compound of interest in understanding the molecular mechanisms of cancer development.
  • Environmental Impact: Like many polycyclic aromatic hydrocarbons, it arises from the incomplete combustion of organic materials, raising significant concerns regarding air and soil pollution.
  • Analytical Applications: This compound can serve as a marker for assessing environmental exposure to polycyclic aromatic hydrocarbons, often found in industrial waste and urban emissions.

Moreover, the compound exhibits unique chemical properties due to the presence of the hydroxyl group. This modification can influence its reactivity and interactions with biological systems, emphasizing the importance of studying its properties in relation to health risks.

In summary, benzo[a]pyren-8-ol not only plays a crucial role in furthering our understanding of environmental health but also serves as a reminder of the complexities surrounding chemical exposure. As researchers continue to explore its effects and pathways, this compound highlights the intricate connections between chemistry, health, and our environment.

Synonyms
benzo[a]pyren-8-ol
13345-26-1
8-Hydroxybenzo[a]pyrene
Benzo(a)pyren-8-ol
BENZO(a)PYRENE, 8-HYDROXY-
8-Hydroxy-3,4-benzopyrene
Benzo[pqr]tetraphen-8-ol
CHEBI:34493
8-HYDROXYBENZO(A)PYRENE
8-Hydroxy-benzo(a)pyrene
BRN 2379758
8-Hydroxy benzo[a]pyrene
BIDD:ER0355
CHEMBL1908057
SCHEMBL28382333
DTXSID00158116
AKOS015905883
CS-0098958
NS00124225
Q27116106
pentacyclo[10.6.2.0?,?.0?,??.0??,??]icosa-1(18),2,4,6,8,10,12,14,16,19-decaen-5-ol