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Benzo[a]pyrene-6-methanol

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Identification
Molecular formula
C18H12O
CAS number
29218-53-7
IUPAC name
benzo[b]pyren-6-ylmethanol
State
State

At room temperature, Benzo[b]pyren-6-ylmethanol is a solid. It remains in this physical state well above typical room temperature conditions, showing stability as a solid up to its melting point.

Melting point (Celsius)
105.00
Melting point (Kelvin)
378.15
Boiling point (Celsius)
568.00
Boiling point (Kelvin)
841.15
General information
Molecular weight
268.34g/mol
Molar mass
268.3420g/mol
Density
1.2426g/cm3
Appearence

Benzo[b]pyren-6-ylmethanol typically appears as a yellowish crystalline solid. Its color and solid-state crystalline nature are in line with many polycyclic aromatic hydrocarbons, which often exhibit strong coloration due to extended conjugated systems.

Comment on solubility

Solubility of Benzo[b]pyren-6-ylmethanol

Benzo[b]pyren-6-ylmethanol, a polycyclic aromatic hydrocarbon derivative, offers intriguing characteristics concerning its solubility. This compound exhibits a moderate solubility profile, influenced by several factors:

  • Polar vs. Non-Polar Solvent: Due to the presence of the hydroxymethyl group (-CH2OH), benzo[b]pyren-6-ylmethanol shows enhanced solubility in polar solvents like methanol and ethanol while remaining less soluble in non-polar solvents such as hexane.
  • Temperature Dependence: The solubility may increase with temperature, often leading to improved dissolution rates, which is crucial in various experimental applications.
  • Concentration Effects: At higher concentrations, aggregative properties may arise, potentially affecting the compound's overall solubility behavior.

Furthermore, it is essential to note that solubility is a key factor in determining the bioavailability and environmental behavior of benzo[b]pyren-6-ylmethanol. Understanding these solubility dynamics is crucial for applications in fields such as toxicology and pharmacology.

In summary, the solubility of benzo[b]pyren-6-ylmethanol is shaped by its molecular structure and the surrounding solvent environment, making it an interesting subject for further investigation.

Interesting facts

Fascinating Insights about Benzo[b]pyren-6-ylmethanol

Benzo[b]pyren-6-ylmethanol is a compound that falls within the category of polycyclic aromatic hydrocarbons (PAHs), a group notorious for their complex structures and intriguing properties. Here are some captivating aspects of this compound:

  • Source of Interest: Benzo[b]pyren-6-ylmethanol is derived from the oxidative transformation of benzo[b]pyrene, a well-known environmental pollutant and a significant concern due to its carcinogenic properties. This shift from a harmful compound to a potential probe for studying biochemical interactions is noteworthy.
  • Biological Relevance: This compound is studied for its implications in biological systems. Researchers are particularly interested in how benzo[b]pyren-6-ylmethanol may interact with cellular pathways and its potential role in modulating enzymatic activities.
  • Mechanistic Insights: Investigations into this compound may reveal important mechanistic insights regarding its behavior in biological environments and how it contributes to the overall toxicity of related compounds.
  • Phytotoxic Studies: It is suggested that benzo[b]pyren-6-ylmethanol can serve as a model compound in phytotoxicity studies, aiding in the understanding of how PAHs affect plant growth and development.
  • Potential Therapeutic Approaches: Some researchers are exploring the possibility that modifications of such compounds could lead to novel therapeutic agents with anticancer properties, capitalizing on their structural attributes while minimizing toxicity.

In summary, benzo[b]pyren-6-ylmethanol is more than just a derivative of a pollutant; it opens doors to various fields of research, from environmental chemistry to medicinal applications. As the scientific community delves deeper into the intriguing world of PAHs, compounds like benzo[b]pyren-6-ylmethanol will undoubtedly play crucial roles in shaping our understanding of both chemical behaviors and biological impacts.

Synonyms
21247-98-3
6-(Hydroxymethyl)benzo[a]pyrene
6-Hydroxymethylbenzo(a)pyrene
BENZO(a)PYRENE-6-METHANOL
6-(Hydroxymethyl)benzo(a)pyrene
9L76EWQ6Q3
6-Hydroxymethylbenzo[A]Pyrene
DTXSID70175491
RefChem:104092
6-HMBP
6-hydroxymethanolbenzo(a)pyrene
DTXCID2097982
benzo[b]pyren-6-ylmethanol
Benzo(a)pyrene, 6-hydroxymethyl-
Benzo[a]pyren-6-ylmethanol
BENZO(A)PYREN-6-YLMETHANOL
CCRIS 1079
BRN 2218844
UNII-9L76EWQ6Q3
SCHEMBL936443
CHEMBL170043
FJQLVOHCPDYIFE-UHFFFAOYSA-N
HYDROXYMETHYLBENZO(A)PYRENE, 6-
NS00115925