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Benzothiophen-4-ol

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Identification
Molecular formula
C8H6OS
CAS number
2668-25-1
IUPAC name
benzothiophen-4-ol
State
State

At room temperature, benzothiophen-4-ol exists as a solid.

Melting point (Celsius)
91.00
Melting point (Kelvin)
364.15
Boiling point (Celsius)
275.80
Boiling point (Kelvin)
548.95
General information
Molecular weight
150.19g/mol
Molar mass
150.1930g/mol
Density
1.2412g/cm3
Appearence

Benzothiophen-4-ol is a white to off-white crystalline solid.

Comment on solubility

Solubility of Benzothiophen-4-ol

Benzothiophen-4-ol, with its complex structure, exhibits varying solubility characteristics that are of interest in chemical applications. The solubility of this compound is influenced by several factors, including:

  • Polarity: The presence of the hydroxyl (-OH) group contributes to some polarity, facilitating solubility in polar solvents.
  • Functional Groups: The benzothiophene ring can interact with non-polar solvents, making it less soluble in water but more compatible with organic solvents.
  • Temperature: Like many organic compounds, solubility may increase with temperature, enhancing its interaction in various solvents.

In practical terms, it has been observed that:

  • Benzothiophen-4-ol is soluble in organic solvents such as ethanol, methanol, and acetone.
  • It shows limited solubility in water, which may restrict its application in aqueous environments.
  • The compound's solubility can generally be described as moderate, providing utility in organic synthesis and as an intermediate in chemical reactions.

Understanding its solubility behavior is crucial, as it dictates its applications in chemical processes and formulations. As noted in chemical literature, “The solubility profile underpins the interactions and behaviors of compounds in diverse environments.”

Interesting facts

Interesting Facts about Benzothiophen-4-ol

Benzothiophen-4-ol is a fascinating organic compound that holds significant interest in various fields of research and application. Its unique structure features a fusion of benzene and thiophene rings, presenting a variety of intriguing properties and potential uses.

Key Characteristics

  • Biological Activity: Benzothiophen-4-ol has been the subject of studies related to its bioactivity. Certain derivatives exhibit anti-inflammatory and antioxidant properties, making them potential candidates for pharmaceutical applications.
  • Photovoltaic Applications: In organic electronics, compounds similar to benzothiophen-4-ol are being explored for their roles in organic solar cells, enhancing light absorption and conversion efficiency.
  • Environmental Significance: Research into its derivatives has revealed potential as environmental sensors, with their ability to detect and quantify pollutants due to their response to various chemical environments.

Significant Insights

The compound's versatility can be attributed to its ability to undergo various chemical reactions, including oxidation and substitution reactions. This is pivotal in synthetic chemistry, allowing chemists to create a wide array of functionalized derivatives with tailored properties for specific applications.

Moreover, it plays a role in material science due to its ability to form conducting polymers, which have implications in developing new electronic devices. As noted by researchers in the field, "Exploration of benzothiophenes can lead to breakthroughs in energy-related technologies."


In summary, benzothiophen-4-ol is not just a compound of theoretical interest but one with practical applications that may contribute to advancements in pharmaceuticals, electronics, and environmental science.

Synonyms
Benzo[b]thiophene-4-ol
1-Benzothiophene-4-ol
4-HYDROXYBENZOTHIOPHENE
Benzo(b)thiophene-4-ol
4-Hydroxybenzo[b]thiophene
4-Hydroxybenzo(b)thiophene
S373YK9TXM
BRN 0114904
EINECS 222-776-1
DTXSID10189678
DTXCID70112169
222-776-1
5-17-04-00199 (beilstein handbook reference)
bmrzgynnztveck-uhfffaoysa-n
benzo[b]thiophen-4-ol
3610-02-4
1-Benzothiophen-4-ol
benzo[b)thiophen-4-ol
4-benzothienol
4-hydroxybenzo-thiophene
1-Benzothiophen-4-ol #
UNII-S373YK9TXM
SCHEMBL911513
MFCD01663547
AKOS005146463
AC-31028
AS-36399
DB-022568
CS-0008967
NS00047709
EN300-219175
Z1198157413
361-02-4