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Lidocaine

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Identification
Molecular formula
C14H22N2O2
CAS number
137-58-6
IUPAC name
benzyl 2-[(dimethylamino)methyl]-2-phenyl-butanoate
State
State

At room temperature, lidocaine is typically in a solid state. However, it can also be formulated into a liquid solution for medical usage as an injectable or topical anesthetic.

Melting point (Celsius)
66.00
Melting point (Kelvin)
339.00
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.00
General information
Molecular weight
234.34g/mol
Molar mass
234.3390g/mol
Density
1.0260g/cm3
Appearence

Lidocaine is typically a white crystalline powder. It is odorless and has a slightly bitter taste. When used in pharmaceutical formulations, it may be present as a clear and colorless solution.

Comment on solubility

Solubility of Benzyl 2-[(Dimethylamino)methyl]-2-phenyl-butanoate

The solubility of benzyl 2-[(dimethylamino)methyl]-2-phenyl-butanoate can be influenced by several factors, making it essential to understand its behavior in various solvents. Generally, the solubility properties can vary depending on:

  • Solvent Polarity: This compound tends to exhibit increased solubility in polar solvents such as methanol, ethanol, and dimethyl sulfoxide (DMSO).
  • Temperature: As the temperature rises, the solubility often increases due to enhanced molecular movement and interaction.
  • pH Levels: The solubility may also be affected by the pH of the solution, particularly because of the presence of dimethylamino groups which can interact with protons.

In practice, the statement, "Like dissolves like," captures the essence of solvent interactions; polar solvents can efficiently solubilize polar compounds and vice versa. For benzyl 2-[(dimethylamino)methyl]-2-phenyl-butanoate:

  • It is likely to be poorly soluble in non-polar solvents such as hexane or toluene.
  • Understanding its solubility can be crucial for applications in pharmaceuticals and chemical formulations where appropriate solvent choice is pivotal.

In summary, the solubility of benzyl 2-[(dimethylamino)methyl]-2-phenyl-butanoate is a complex interplay between its structural features and the characteristics of the solvent, and careful experimentation is recommended to ascertain precise values in different environments.

Interesting facts

Interesting Facts about Benzyl 2-[(Dimethylamino)methyl]-2-phenyl-butanoate

Benzyl 2-[(dimethylamino)methyl]-2-phenyl-butanoate is a fascinating compound in the realm of organic chemistry, due in part to its unique structure and potential applications. Here are some key points to consider:

  • Diverse Applications: This compound is known for its utility in pharmaceutical research, particularly in developing analgesics and anti-inflammatory agents. Compounds with similar structures often show promising biological activities.
  • Structural Complexity: The presence of the dimethylamino group combined with the benzyl and phenyl moieties creates an intriguing molecular architecture, which can lead to interesting reactivity patterns.
  • Synthetic Pathways: Several synthetic methods can yield benzyl 2-[(dimethylamino)methyl]-2-phenyl-butanoate. For instance, it can be synthesized through the esterification of butanoic acid derivatives, showcasing the versatility of carboxylic acid reactions.
  • Role in Drug Discovery: Due to its complex structure, this compound serves as a template for synthesizing new analogs, helping chemists design drugs that could potentially optimize efficacy and reduce side effects.

As noted by chemists, “Understanding the intricacies of such compounds not only expands our knowledge of organic chemistry but also opens the door to innovation in medicinal chemistry.”

Overall, with its multifaceted properties and applications, benzyl 2-[(dimethylamino)methyl]-2-phenyl-butanoate is a compound that certainly merits attention for future research and development.