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Lidocaine hydrochloride

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Identification
Molecular formula
C14H23ClN2O2
CAS number
6108-05-0
IUPAC name
benzyl 2-[(dimethylamino)methyl]-2-phenyl-butanoate;hydrochloride
State
State

At room temperature, lidocaine hydrochloride is typically found in a solid state as a powder. While it can be dissolved in solvents for various uses, it naturally occurs as a solid crystalline powder under normal conditions.

Melting point (Celsius)
80.00
Melting point (Kelvin)
353.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
324.90g/mol
Molar mass
324.9040g/mol
Density
1.1590g/cm3
Appearence

Lidocaine hydrochloride appears as a white crystalline powder. It is odorless and has a slightly bitter taste. Being a crystalline substance, it reflects light and appears shiny.

Comment on solubility

Solubility of Benzyl 2-[(Dimethylamino)methyl]-2-phenyl-butanoate Hydrochloride

The solubility of benzyl 2-[(dimethylamino)methyl]-2-phenyl-butanoate; hydrochloride can be influenced by several factors, making it a compound of interest in various applications. Here are some key points regarding its solubility:

  • Solvent Interaction: This compound is likely to be more soluble in polar solvents, such as water and methanol, due to the presence of the hydrocholoride ion.
  • pH Sensitivity: The solubility can vary with pH levels; typically, salts such as hydrochlorides are more soluble in acidic conditions than in neutral or basic environments.
  • Temperature Effects: As with many chemical compounds, an increase in temperature generally enhances solubility. Thus, warming the solvent could aid in dissolving this compound more effectively.
  • Structural Factors: The bulky phenyl groups and dimethylamino functional group can affect solubility, potentially leading to lower solubility compared to smaller, less complex amine compounds.

In summary, the solubility of this compound is multifaceted and can be categorized as good in appropriate solvents and conditions, but careful consideration of environmental factors is essential for practical applications.

Interesting facts

Interesting Facts about Benzyl 2-[(Dimethylamino)methyl]-2-phenyl-butanoate Hydrochloride

Benzyl 2-[(dimethylamino)methyl]-2-phenyl-butanoate hydrochloride is a fascinating compound that plays a significant role in various fields of chemistry and pharmaceuticals. Here are some intriguing aspects:

  • Pharmaceutical Relevance: This compound is often investigated for its potential applications in medicinal chemistry, particularly in the development of novel therapeutic agents.
  • Structure-Activity Relationship: Understanding the structure of this compound is crucial, as slight modifications in its structure can drastically alter its biological activities and pharmacokinetics. The presence of the dimethylamino group is pivotal for its interactions.
  • Safety and Handling: Due to the presence of a hydrochloride group, proper safety measures are essential when handling this compound. It is always important to approach such substances with caution to ensure safe laboratory practices.
  • Synthetic Pathways: The synthesis of benzyl 2-[(dimethylamino)methyl]-2-phenyl-butanoate hydrochloride presents interesting challenges and opportunities. Chemists often explore various synthetic routes that can yield this compound efficiently.
  • Research Potential: Ongoing studies continue to explore this compound's full range of biological activities, highlighting the importance of its derivatives in drug discovery and development.
  • Applications: Beyond pharmaceuticals, there’s potential for applications in fields like agriculture and materials science, owing to its unique chemical properties.

The exploration of benzyl 2-[(dimethylamino)methyl]-2-phenyl-butanoate hydrochloride represents a blend of creative synthesis, analytical techniques, and biological evaluation, making it a compound of significant interest in both scientific research and practical applications.

Synonyms
DL 219
BUTYRIC ACID, 2-(DIMETHYLAMINOMETHYL)-2-PHENYL-, BENZYL ESTER, HYDROCHLORIDE
510-83-8
Benzyl-beta-dimethyl-amino-alpha-phenyl-alpha-ethyl-propionate hydrochloride
Benzeneacetic acid, alpha-((dimethylamino)methyl)-alpha-ethyl-, phenylmethyl ester, HCl
Hydratropic acid, beta-(dimethylamino)-alpha-ethyl-, benzyl ester, hydrochloride
Hydratropic acid, beta-(dimethylamino)-alpha-ethyl-, benzyl ester, hydrochloride (8CI)
DTXSID80965284
Benzyl 2-[(dimethylamino)methyl]-2-phenylbutanoate--hydrogen chloride (1/1)