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Benzyl chloroformate

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Identification
Molecular formula
C8H7ClO2
CAS number
501-53-1
IUPAC name
benzyl carbonochloridate
State
State

At room temperature, benzyl chloroformate is in a liquid state.

Melting point (Celsius)
-2.40
Melting point (Kelvin)
270.75
Boiling point (Celsius)
192.00
Boiling point (Kelvin)
465.15
General information
Molecular weight
154.57g/mol
Molar mass
154.5740g/mol
Density
1.2120g/cm3
Appearence

Benzyl chloroformate appears as a colorless to pale yellow liquid with a pungent odor. It is typically used in chemical synthesis and is part of the reagents used in various organic reactions.

Comment on solubility

Solubility of Benzyl Carbonochloridate

Benzyl carbonochloridate, with the chemical formula C8H7ClO2, is known for its unique solubility characteristics. Understanding the solubility of this compound is crucial for its applications in various chemical reactions.

In general, the solubility of benzyl carbonochloridate can be summarized as follows:

  • Solvent Compatibility: Benzyl carbonochloridate exhibits moderate solubility in organic solvents such as dichloromethane and acetone.
  • Polar vs. Nonpolar: As a somewhat polar compound, it tends to be less soluble in highly polar solvents like water.
  • Temperature Dependence: Its solubility can increase with temperature, making it more soluble in heated organic solvents.

It is important to note that the solubility is influenced by several factors, including:

  1. Molecular Structure: The presence of the carbonochloridate functional group impacts interactions with solvents.
  2. Concentration: Higher concentrations may lead to precipitation in less compatible solvents.
  3. Presence of Other Compounds: The solubility can vary when mixed with other substances, due to competitive interactions.

In conclusion, while benzyl carbonochloridate may not be highly soluble in water, its behavior in organic solvents offers valuable flexibility for chemical syntheses. As quoted, "Understanding solubility is the key to unlocking the potential of chemical compounds."

Interesting facts

Interesting Facts About Benzyl Carbonochloridate

Benzyl carbonochloridate is a fascinating compound that belongs to the class of carbonates, specifically known for its application in organic synthesis. Here are some intriguing aspects of this compound:

  • Versatile Reagent: This compound is often utilized as a carbonylating agent, which plays a crucial role in the synthesis of esters and other derivatives. Its ability to introduce the carbonochloridate group makes it a valuable tool for chemists.
  • Diverse Applications: Benzyl carbonochloridate finds use in the synthesis of various organic compounds, including pharmaceuticals and agrochemicals. Its reactivity allows for the construction of complex molecular architectures.
  • Synthetic Pathways: One of the notable reactions involving benzyl carbonochloridate is its participation in the synthesis of benzyl carbamates. This reaction is significant in designing biologically active molecules.
  • Safety and Handling: Due to its reactive nature, handling benzyl carbonochloridate requires caution. It's important to use appropriate protective equipment and to work in a well-ventilated area when conducting experiments involving this compound.

The Importance of Understanding Reactivity

Understanding the reactivity of benzyl carbonochloridate is key for chemists looking to make advances in organic synthesis. As noted by researchers in the field, “The ability to manipulate reaction conditions can lead to vastly different product outcomes, showcasing the compound's versatility.” This highlights the significance of knowledge in reaction dynamics when working with such reactive species.

In conclusion, benzyl carbonochloridate is not just a compound with interesting properties; it serves as a fundamental building block in the world of organic chemistry, enabling the synthesis of a wide array of chemical compounds.

Synonyms
BENZYL CHLOROFORMATE
Benzyl carbonochloridate
Carbobenzoxy chloride
Cbz chloride
Benzyloxycarbonyl chloride
Carbobenzyloxy chloride
Carbonochloridic acid, phenylmethyl ester
Chloroformic acid, benzyl ester
Benzylcarbonochloridate
NSC 83466
CCRIS 2599
HSDB 364
phenylmethyl chloroformate
(benzyloxy)carbonyl chloride
EINECS 207-925-0
UN1739
UNII-170BP0DD31
carbonochloridic acid phenylmethyl ester
DTXSID9027158
NSC-83466
DTXCID607158
CARBOBENZOXY CHLORIDE [MI]
EC 207-925-0
BENZYL CHLOROFORMATE [HSDB]
Chloroformic acid, phenylmethyl ester
UN 1739
Formic acid, chlorobenzyl ester
Formic acid, chloro, benzyl ester
hsdajnmjomsnev-uhfffaoysa-n
501-53-1
Benzyl chlorocarbonate
Benzylcarbonyl chloride
Cbz-Cl
Z-Cl
Formic acid, chloro-, benzyl ester
Chloroformic Acid Benzyl Ester
Z-chloride
MFCD00000640
170BP0DD31
benzyloxycarbonylchloride
Bzcf
Cbz-chloride
benylchloroformate
benzylchoroformate
benzyl chlorformate
benzyl choroformate
BnOCOCl
carbobenzoxychioride
carbobenzoxychloride
benzyl chioroformate
benzyl-chloroformate
benzylchloro-formate
CBZCl
benzylchlorocarbonate
carbobenzyloxychloride
Benzyl chloro-formate
Benzyl chloroform ate
benzyl carbonchloridate
Benzyl chloroformate (50% in toluene)
BnOC(O)Cl
benzoxycarbonyl chloride
Benzyl chloridocarbonate
phenylmethylchlorocarbonate
Benzyl chloridocarbonate #
benzyloxy carbonyl chloride
SCHEMBL960
WLN: GVO1R
(phenylmethyl)carbonochloridate
(phenylmethyl) carbonochloridate
Carbobenzoxy chloride;Z-chloride
CHEMBL1581748
AAA50153
Chlorocarbonic acid monobenzyl ester
NSC83466
Tox21_201072
BBL011517
STL146633
AKOS000120065
NCGC00090933-01
NCGC00090933-02
NCGC00258625-01
CAS-501-53-1
PD118845
VS-02967
Benzyl chloroformate (30-35% in Toluene)
DB-002647
B3021
NS00003708
Benzyl chloroformate [UN1739] [Corrosive]
EN300-19843
M02865
Q419534
F0001-1308