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Galantamine Hydrobromide

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Identification
Molecular formula
C20H24N2O2
CAS number
1953-04-4
IUPAC name
benzyl N-[(4,7-dimethyl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinolin-9-yl)methyl]carbamate
State
State

At room temperature, Benzyl N-[(4,7-dimethyl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinolin-9-yl)methyl]carbamate is in a solid state. It is stable under normal temperatures and pressures.

Melting point (Celsius)
126.00
Melting point (Kelvin)
399.20
Boiling point (Celsius)
572.50
Boiling point (Kelvin)
845.70
General information
Molecular weight
341.46g/mol
Molar mass
287.3610g/mol
Density
1.2700g/cm3
Appearence

Benzyl N-[(4,7-dimethyl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinolin-9-yl)methyl]carbamate typically appears as a crystalline solid. The compound may be off-white to pale yellow in color. It is generally odourless and may have a bitter taste.

Comment on solubility

Solubility of Benzyl N-[(4,7-dimethyl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinolin-9-yl)methyl]carbamate

The solubility of the compound benzyl N-[(4,7-dimethyl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinolin-9-yl)methyl]carbamate (C20H24N2O2) can be influenced by several factors. Understanding its solubility is essential for applications in pharmacology and material science. Here are some key points to consider:

  • Solvent Type: The solubility of this compound is likely to vary significantly between polar and non-polar solvents. Polar solvents may enhance solubility due to potential hydrogen bonding.
  • Temperature Effects: As with many compounds, solubility often increases with temperature. It would be beneficial to investigate solubility at various temperatures.
  • pH Dependency: The presence of functional groups may lead to different solubility profiles based on the pH of the solution, particularly if ionizable groups are present.
  • Chemical Structure: The bulky hexahydroindole moiety may impact the overall interaction with solvent molecules, potentially creating a more hydrophobic environment.

In conclusion, while the specific solubility data may be limited, it is crucial to conduct empirical investigations under varied conditions to fully elucidate the solubility characteristics of this complex compound. Its unique structure suggests possibilities for the formation of complexes or aggregates that might also impact its solubility.

Interesting facts

Interesting Facts About Benzyl N-[(4,7-dimethyl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinolin-9-yl)methyl]carbamate

Benzyl N-[(4,7-dimethyl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinolin-9-yl)methyl]carbamate is a fascinating compound with numerous potential applications in the field of medicinal chemistry. Here are some interesting facts:

  • Structure Complexity: This compound features a unique structural framework, including a hexahydroindoloquinoline moiety that contributes to its biological activity.
  • Biological Significance: Compounds bearing the indole structure are often studied for their pharmacological effects, including antitumor and antimicrobial properties, making this compound of great interest for drug development.
  • Potential Therapeutic Uses: Given its structural characteristics, this compound might possess activity against various diseases, especially those involving steroid synthesis or enzyme inhibition.
  • Research Insights: The carbamate functional group is known to enhance solubility and bioavailability, which could improve the therapeutic efficacy of the compound.
  • Future Directions: Ongoing research may uncover potential derivatives of this compound, leading to the design of more effective drugs targeting specific biological pathways.

In the words of noted chemist Linus Pauling, “The best way to have a good idea is to have a lot of ideas.” This compound exemplifies the spirit of innovative chemistry and the potential breakthroughs that come from exploring complex molecular designs.

Overall, benzyl N-[(4,7-dimethyl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinolin-9-yl)methyl]carbamate represents a stimulating area of research within organic chemistry and pharmacology, inviting scientists and students to delve deeper into its mysteries.

Synonyms
Metergoline phenylmethyl ester
Oprea1_664524
BDBM86523
CHEBI:91619
DTXSID50860212
HMS3266O14
HMS3373D15
benzyl N-[[(6aR,9S,10aR)-4,7-dimethyl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinolin-9-yl]methyl]carbamate
NSC_28693
AKOS030241625
CAS_17692-51-2
L000396
Benzyl [(1,6-dimethylergolin-8-yl)methyl]carbamate
BRD-A30435184-001-01-5
Q27163448
benzyl N-[(4,7-dimethyl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinolin-9-yl)methyl]carbamate
N-[(4,7-dimethyl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinoline-9-yl)methyl]carbamic acid (phenylmethyl) ester