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Piperidone

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Identification
Molecular formula
C11H20N2O
CAS number
2955-88-6
IUPAC name
bis(1-piperidyl)methanone
State
State

At room temperature, bis(1-piperidyl)methanone is a liquid. It possesses a faint amine-like odor and is moderately soluble in water. It is stable under normal temperatures and pressures.

Melting point (Celsius)
-8.00
Melting point (Kelvin)
265.15
Boiling point (Celsius)
273.00
Boiling point (Kelvin)
546.15
General information
Molecular weight
168.26g/mol
Molar mass
168.2640g/mol
Density
1.0330g/cm3
Appearence

Bis(1-piperidyl)methanone, also known as piperidone, typically appears as a colorless to pale yellow liquid. It is often used in organic synthesis and can slowly darken on exposure to air and light.

Comment on solubility

Solubility of bis(1-piperidyl)methanone

bis(1-piperidyl)methanone, a compound of interest, exhibits unique solubility properties that are important for its applications in various fields. Understanding its solubility can be crucial for predicting its behavior in different environments and formulations.

General Solubility Characteristics

The solubility of bis(1-piperidyl)methanone can be characterized by several significant factors:

  • Polarity: Due to the presence of amine functional groups from the piperidine units, bis(1-piperidyl)methanone is likely to have moderate polarity, which influences its solubility in polar solvents.
  • Solvent Interaction: It is generally soluble in polar protic solvents like water and alcohols, and may have limited solubility in nonpolar solvents.
  • Temperature Dependency: Like many organic compounds, its solubility could increase with rising temperature, facilitating a better dissolution process in various solvents.

In practical applications, the solubility of bis(1-piperidyl)methanone can be crucial. For example, its effectiveness in reactions and formulations might be contingent upon reaching sufficient concentrations in the chosen solvent. Such behaviors are best summarized by the adage: "Like dissolves like." This emphasizes the importance of matching solubility properties with solvent characteristics in order to maximize the compound's utility.

Overall, understanding the solubility of bis(1-piperidyl)methanone lays the groundwork for its effective application in chemical processes, pharmaceuticals, and materials science.

Interesting facts

Exploring Bis(1-piperidyl)methanone

Bis(1-piperidyl)methanone is a fascinating compound primarily known for its relevance in medicinal chemistry. This compound is composed of two 1-piperidyl groups attached to a carbonyl group, making it an interesting subject for various chemical studies.

Key Features:

  • Diverse Biological Applications: Bis(1-piperidyl)methanone serves as a building block for synthesizing numerous pharmaceutical compounds, particularly those with potential neuroactive and antimicrobial properties.
  • Versatility in Synthesis: The presence of the piperidine ring confers unique reactivity, allowing chemists to modify or build upon this structure to create derivatives with enhanced biological activity.
  • Research Interest: Research into compounds like bis(1-piperidyl)methanone often focuses on their mechanisms of action, target affinity, and interactions with biological systems, providing insights into drug design and development.

Research Significance:

This compound’s structure can provide hints on how we can tackle various diseases. For example, the ability to modify the piperidyl groups could lead to breakthroughs in treating neurological disorders. As stated by many researchers, “Exploration of such compounds is essential in the quest for effective therapies.”

In summary, bis(1-piperidyl)methanone is not just a compound with a complex structure; it is a gateway to numerous potential advancements in the pharmaceutical field, making it an excellent area of study for both chemists and students alike.

Synonyms
1,1'-Carbonyldipiperidine
5395-04-0
Bis(pentamethylene)urea
N,N'-Carbonylbis(piperidine)
Piperidine, 1,1'-carbonylbis-
PIPERIDINE, 1,1'-CARBONYLDI-
N,N,N',N'-Bispentamethyleneurea
Bis(1-piperidyl) ketone
NSC 3145
N,N,N',N'-Bispentamethylene urea
EINECS 226-407-5
ST5T93T7OJ
Methanone, di-1-piperidinyl-
BRN 0144183
N,N,N',N'-Bis(cyclopentamethylene)urea
AI3-17308
NSC-3145
dipiperidin-1-ylmethanone
DI-1-PIPERIDINYLMETHANONE
DTXSID70202236
5-20-02-00486 (Beilstein Handbook Reference)
DTXCID70124727
Piperidine, 1,1'-carbonylbis-(9CI)
226-407-5
di(piperidin-1-yl)methanone
piperidinoketone
1,1-CARBONYLDIPIPERIDINE
NSC3145
GOY
Piperidine,1'-carbonyldi-
UNII-ST5T93T7OJ
Piperidine,1'-carbonylbis-
Bis(piperidin-1-yl)methanone
CHEMBL11960
SCHEMBL446167
N,N',N'-Bispentamethylene urea
SNOJOKOVTYPHMC-UHFFFAOYSA-
WLN: T6NTJ AV- AT6NTJ
1,1'-Carbonyldipiperidine, 97%
MFCD00006482
AKOS015913686
1-(1-Piperidinylcarbonyl)piperidine #
SB41534
DB-052437
NS00032889
A914713
InChI=1/C11H20N2O/c14-11(12-7-3-1-4-8-12)13-9-5-2-6-10-13/h1-10H2