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4-Fluorophenylmethylbischloroethylammonium chloride

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Identification
Molecular formula
C11H15Cl2FN
CAS number
23426-49-7
IUPAC name
bis(2-chloroethyl)-[(4-fluorophenyl)methyl]ammonium;chloride
State
State

At room temperature, 4-Fluorophenylmethylbischloroethylammonium chloride is typically in a solid state as a white crystalline powder.

Melting point (Celsius)
191.00
Melting point (Kelvin)
464.00
Boiling point (Celsius)
295.50
Boiling point (Kelvin)
568.70
General information
Molecular weight
286.15g/mol
Molar mass
286.1790g/mol
Density
1.1900g/cm3
Appearence

The compound appears as a crystalline powder that is typically white in color. It is often hygroscopic, meaning it can absorb moisture from the air.

Comment on solubility

Solubility of bis(2-chloroethyl)-[(4-fluorophenyl)methyl]ammonium;chloride

The solubility of bis(2-chloroethyl)-[(4-fluorophenyl)methyl]ammonium;chloride can be characterized by several key points:

  • General Solubility: This compound is typically soluble in polar solvents, such as water and alcohols, due to the presence of its ionic chloride component.
  • Polar Nature: The ionic nature of the chloride anion enhances its solubility in aqueous solutions, allowing it to dissociate into its constituent ions.
  • Temperature Dependency: As with many salts, solubility may increase with temperature; thus, higher temperatures can lead to greater dissolution rates.
  • Solvent Influence: The choice of solvent can significantly affect solubility; organic solvents may have varying abilities to dissolve this compound.

Overall, you can expect bis(2-chloroethyl)-[(4-fluorophenyl)methyl]ammonium;chloride to be moderately to highly soluble in water, influenced by its structural characteristics and the solvents used.

Interesting facts

Interesting Facts About Bis(2-Chloroethyl)-[(4-Fluorophenyl)methyl]ammonium Chloride

Bis(2-chloroethyl)-[(4-fluorophenyl)methyl]ammonium chloride is a fascinating compound that has garnered attention in various fields of chemistry, particularly in medicinal chemistry. Here are some notable points:

  • Pharmaceutical Relevance: This compound is often studied for its potential use as an anti-cancer agent. Its structure suggests it may interact with biological systems in ways that could inhibit cell proliferation.
  • Mechanism of Action: The presence of the chloroethyl groups can facilitate alkylation of DNA, potentially leading to cellular apoptosis – a mechanism that is crucial in cancer therapies.
  • Fluorine's Role: The incorporation of the fluorophenyl group enhances molecular stability and influences the compound's overall electronic properties, making it more effective in its biological activities.
  • Research Applications: Scientists often utilize this compound in biodiversity research and synthetic methodologies, using it as a starting material for creating more complex molecules.
  • Toxicological Studies: Its chlorinated nature means that this compound is also a subject of toxicology studies, where researchers assess its potential side effects and environmental impact.

In conclusion, bis(2-chloroethyl)-[(4-fluorophenyl)methyl]ammonium chloride is not just another chemical; it represents a bridge between chemistry and medicine, showcasing how structural innovations can lead to therapeutic advances. As one quote highlights, "The structures of these compounds can reveal incredible potential in drug design."

Through ongoing research, the hope is to unlock even more secrets held within this and similar compounds, pushing the boundaries of what we understand in pharmacology and synthetic chemistry.

Synonyms
p-Fluoro-di-(2-chloroethyl)-benzylamine hydrochloride
1645-07-4
NSC 72401
N,N-Bis(2-chloroethyl)-p-fluorobenzylamine hydrochloride
BENZYLAMINE, N,N-BIS(2-CHLOROETHYL)-p-FLUORO-, HYDROCHLORIDE