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Ammonium chloride

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Identification
Molecular formula
C11H15Cl2IN
IUPAC name
bis(2-chloroethyl)-[(4-iodophenyl)methyl]ammonium;chloride
State
State

At room temperature, bis(2-chloroethyl)-[(4-iodophenyl)methyl]ammonium chloride is generally found in a solid state. It is often utilized in chemical laboratories and for specialized applications.

Melting point (Celsius)
338.00
Melting point (Kelvin)
611.15
Boiling point (Celsius)
329.00
Boiling point (Kelvin)
602.15
General information
Molecular weight
374.06g/mol
Molar mass
374.6700g/mol
Density
1.6700g/cm3
Appearence

Bis(2-chloroethyl)-[(4-iodophenyl)methyl]ammonium chloride typically appears as a solid substance, often found in the form of a white or off-white crystalline powder. The compound's exact appearance can be influenced by the specific chemical structure and purity.

Comment on solubility

Solubility of bis(2-chloroethyl)-[(4-iodophenyl)methyl]ammonium;chloride

The solubility of bis(2-chloroethyl)-[(4-iodophenyl)methyl]ammonium;chloride can be influenced by several factors, including polarity, temperature, and the presence of solvents. Understanding its solubility characteristics is crucial for its utilization in various applications. Here are the key points to consider:

  • Polarity: This compound features both polar and nonpolar attributes due to the chloride ion and the organic portions of the molecule. This can lead to variable solubility in different solvents.
  • Solvent Interactions: It may exhibit solubility in polar solvents such as water or methanol, where the positively charged ammonium group can interact effectively with these solvent molecules.
  • Temperature Effects: Solubility may increase with temperature, meaning that higher temperatures might enhance the dissolution of the compound in solvents.
  • pH Sensitivity: Changes in pH could alter the ionization of the ammonium group, potentially affecting solubility.

In summary, the solubility of bis(2-chloroethyl)-[(4-iodophenyl)methyl]ammonium;chloride is a complex interplay of its chemical structure and environmental conditions. Experimentation in different solvent systems is recommended to determine its precise solubility characteristics.

Interesting facts

Interesting Facts about Bis(2-Chloroethyl)-[(4-Iodophenyl)methyl]ammonium Chloride

The compound bis(2-chloroethyl)-[(4-iodophenyl)methyl]ammonium chloride is a fascinating example of a quaternary ammonium compound that serves multiple purposes in various chemical and biological fields. Its unique structural attributes allow it to function effectively as a reagent and therapeutic agent.

Key Highlights:

  • Dual Action: This compound is notable for its dual-action properties. It is often used in medicinal chemistry due to its ability to target and disrupt cellular functions, making it of interest for developing anti-cancer agents.
  • Quaternary Structure: Being a quaternary ammonium salt, it possesses a permanent positive charge, which significantly enhances its solubility in polar solvents and its interaction with biomolecules.
  • Targeting Capability: The presence of the 4-iodophenyl group lends itself to *specific targeting* within biological systems, making it useful in radioisotope labeling in molecular imaging.
  • Reactivity: The chloroethyl groups are known to be reactive, allowing this compound to participate in alkylation reactions, where it can modify various biological macromolecules.

Moreover, the presence of halogens, such as chlorine and iodine, enhances the reactivity and biological activities of the compound. As quoted by chemists in the field, “The halogen substitutions can dramatically alter the biological pathways, making these compounds of substantial interest in pharmacology.”

This compound also emphasizes the importance of molecular design in the development of new pharmaceuticals, highlighting the interplay between chemical structure and biological activity. Continuous research regarding its efficacy and safety profiles promises to unveil further applications in various domains.


Synonyms
p-Iodo-di-(2-chloroethyl)-benzylamine hydrochloride
25022-84-8
N,N-Bis(2-chloroethyl)-p-iodobenzylamine hydrochloride
BENZYLAMINE, N,N-BIS(2-CHLOROETHYL)-p-IODO-, HYDROCHLORIDE