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Bis(2-chloroethyl) (4-methyl-2-oxo-chromen-7-yl) phosphate

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Identification
Molecular formula
C14H16Cl2O4P
CAS number
78-43-3
IUPAC name
bis(2-chloroethyl) (4-methyl-2-oxo-chromen-7-yl) phosphate
State
State

At room temperature, bis(2-chloroethyl) (4-methyl-2-oxo-chromen-7-yl) phosphate is typically in a liquid state. It is a stable compound under normal conditions, but it should be handled with care due to its chemical reactivity.

Melting point (Celsius)
-20.50
Melting point (Kelvin)
252.70
Boiling point (Celsius)
363.50
Boiling point (Kelvin)
636.70
General information
Molecular weight
342.66g/mol
Molar mass
342.6810g/mol
Density
1.3725g/cm3
Appearence

The compound typically appears as a colorless to pale yellow liquid. It is usually clear and has a mild, characteristic odor.

Comment on solubility

Solubility of Bis(2-chloroethyl) (4-methyl-2-oxo-chromen-7-yl) Phosphate

The solubility of bis(2-chloroethyl) (4-methyl-2-oxo-chromen-7-yl) phosphate is an intriguing aspect worth discussing. This compound, which contains both organic and inorganic moieties, tends to exhibit varying solubility characteristics depending on the solvent used. Generally, one can expect:

  • Solubility in Organic Solvents: Due to its organic structure, this phosphate derivative is likely to be more soluble in non-polar to moderately polar organic solvents such as ether, dichloromethane, and acetone.
  • Limited Water Solubility: The presence of the bulky chromen-7-yl group and the chloroethyl substituents may hinder hydrogen bonding with water, resulting in low solubility in aqueous solutions.

In terms of practical implications, it is important to note that:

  1. Aqueous applications may require the use of surfactants to improve dispersion.
  2. Environmental considerations should be taken into account, as persistent organic pollutants often show low solubility in water yet high affinity for organic matrices.

In summary, while bis(2-chloroethyl) (4-methyl-2-oxo-chromen-7-yl) phosphate exhibits a certain degree of solubility in organic solvents, its limited water solubility may influence its behavior and utility in various chemical processes. Understanding the solubility profile is crucial for both laboratory applications and environmental safety.

Interesting facts

Interesting Facts about Bis(2-chloroethyl) (4-methyl-2-oxo-chromen-7-yl) Phosphate

Bis(2-chloroethyl) (4-methyl-2-oxo-chromen-7-yl) phosphate is a fascinating compound that sits at the intersection of organic chemistry and pharmacology. Here are some intriguing aspects of this compound:

  • Phosphate Group Significance: The presence of the phosphate group makes this compound a candidate for drug development, as phosphates often play a critical role in biochemical pathways.
  • Chlorination: The 2-chloroethyl moieties contribute to its reactivity, providing potential for further chemical transformations, which are essential in synthesizing various pharmaceuticals.
  • Chromone Structure: The 4-methyl-2-oxo-chromen-7-yl part of the compound is derived from chromones, which are known for their diverse biological activities. Many chromone derivatives have displayed anti-inflammatory and anti-cancer properties.
  • Potential Applications: Due to its structure, this compound might be explored for use in designing new therapeutic agents or as a research tool in biological experiments.
  • Research Interests: Many scientists are interested in the structure-activity relationship of compounds like this, aiming to enhance efficacy and decrease toxicity in drug design.

In conclusion, bis(2-chloroethyl) (4-methyl-2-oxo-chromen-7-yl) phosphate embodies the intricate dance between chemistry and medicine. Its unique structure and potential applications offer exciting avenues for research and development that could lead to new therapeutic medications. As the saying goes, "In chemistry, the possibilities are endless."

Synonyms
4394-77-8
Phosphoric acid, bis(2-chloroethyl) 4-methyl-2-oxo-2H-1-benzopyran-7-yl ester
86H 60
COUMARIN, 7-HYDROXY-4-METHYL-, BIS(2-CHLOROETHYL) PHOSPHATE
DTXSID50963151
Bis(2-chloroethyl) 4-methyl-2-oxo-2H-1-benzopyran-7-yl phosphate