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Chlorambucil

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Identification
Molecular formula
C14H19Cl2NO2
CAS number
56-72-4
IUPAC name
bis(2-chloroethyl)-[(5-chloro-2-methoxy-phenyl)methyl]ammonium;chloride
State
State

Chlorambucil is typically in a solid state at room temperature, appearing as a crystalline powder. It is important to store it in its solid form to ensure stability and efficacy.

Melting point (Celsius)
65.00
Melting point (Kelvin)
338.15
Boiling point (Celsius)
267.00
Boiling point (Kelvin)
540.15
General information
Molecular weight
304.20g/mol
Molar mass
304.1950g/mol
Density
1.2700g/cm3
Appearence

Chlorambucil is typically found as a white to faintly yellow crystalline powder. It is slightly soluble in water and methanol, but practically insoluble in non-polar organic solvents. Its appearance can be quite sensitive to handling and storage conditions, which may affect its color and crystalline nature.

Comment on solubility

Solubility of bis(2-chloroethyl)-[(5-chloro-2-methoxy-phenyl)methyl]ammonium;chloride

The solubility of bis(2-chloroethyl)-[(5-chloro-2-methoxy-phenyl)methyl]ammonium;chloride in various solvents can reveal much about its chemical behavior and potential applications. Factors affecting its solubility include:

  • Polarity: The presence of both hydrophobic (aromatic) and hydrophilic (ammonium and chloride) components suggests that this compound might exhibit variable solubility depending on the solvent.
  • Temperature: Solubility may increase with temperature, thus altering its behavior in different conditions.
  • pH Levels: Since the compound contains an ammonium group, its solubility may vary in acidic or basic environments.

Generally, we can expect that:

  • The compound is likely more soluble in polar solvents (such as water or alcohols) due to its ionic nature.
  • However, apolar solvents might lead to reduced solubility, especially given the hydrophobic characteristics of the aromatic group.

In summary, while exact solubility data may need experimental validation, bis(2-chloroethyl)-[(5-chloro-2-methoxy-phenyl)methyl]ammonium;chloride is anticipated to exhibit diverse solubility characteristics based on its structural interplay of hydrophilic and hydrophobic portions.

Interesting facts

Interesting Facts about Bis(2-chloroethyl)-[(5-chloro-2-methoxy-phenyl)methyl]ammonium Chloride

Bis(2-chloroethyl)-[(5-chloro-2-methoxy-phenyl)methyl]ammonium chloride, often referred to as a quaternary ammonium compound, is notable in the field of chemistry for several intriguing reasons:

  • Pharmaceutical Relevance: This compound holds potential applications in pharmaceuticals, particularly as an antimicrobial agent. Its structure allows it to interact with biological membranes, making it effective against certain pathogens.
  • Complex Structure: The presence of both chloroethyl and methoxy groups introduces unique reactivity patterns, leading to diverse chemical properties that can be exploited in various synthetic routes.
  • Quaternary Ammonium Compounds: As a member of the quaternary ammonium family, it showcases the characteristic behavior of cationic surfactants, including increased surface activity and stability in formulations.
  • Potential in Drug Development: Scientists are actively researching compounds like this for their role in drug development. They offer opportunities for designing novel therapeutic agents targeting specific biological processes.
  • Environmental Considerations: Understanding how such compounds interact with the environment is crucial. Their persistence and effects on aquatic life are subjects of ongoing studies.

This compound exemplifies the intersection of chemistry and biology, highlighting the importance of structure-property relationships in the development of useful chemical agents. As the scientific community continues to explore its potential, innovative applications may emerge that address challenges in health and environmental sustainability.

In the words of a renowned chemist, "The pursuit of understanding complex compounds opens the door to invaluable discoveries in both nature and human innovation."

Synonyms
N,N-Bis(2-chloroethyl)-3-chloro-6-methoxybenzylamine hydrochloride
27057-91-6
2-Methoxy-5-chlorobenzyl-bis-(beta-chloroethyl) amine hydrochloride
BENZYLAMINE, N,N-BIS(2-CHLOROETHYL)-3-CHLORO-6-METHOXY-, HYDROCHLORIDE