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Quinuronium chloride

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Identification
Molecular formula
C16H20Cl3N3
CAS number
54-44-2
IUPAC name
bis(2-chloroethyl)-[(5,6-dimethyl-1H-benzimidazol-2-yl)methyl]ammonium;chloride
State
State

At room temperature, quinuronium chloride is in a solid state, forming crystalline structures. It is stable under normal conditions and is typically handled as a powder.

Melting point (Celsius)
127.00
Melting point (Kelvin)
400.15
Boiling point (Celsius)
310.00
Boiling point (Kelvin)
583.15
General information
Molecular weight
365.72g/mol
Molar mass
365.3210g/mol
Density
1.1600g/cm3
Appearence

Quinuronium chloride typically appears as a white to off-white crystalline powder. Its texture is consistent with fine powders, and it is generally uniform in appearance with no distinct odor. It is often used in veterinary medicine, particularly as a trypanocidal agent.

Comment on solubility

Solubility of bis(2-chloroethyl)-[(5,6-dimethyl-1H-benzimidazol-2-yl)methyl]ammonium; chloride

The solubility of bis(2-chloroethyl)-[(5,6-dimethyl-1H-benzimidazol-2-yl)methyl]ammonium; chloride is an intriguing aspect of this compound. As a quaternary ammonium salt, it exhibits unique solubility characteristics, influenced by its structure and ionic nature.

Factors Affecting Solubility:

  • Ionic Nature: Being a salt, it is generally soluble in polar solvents, particularly water.
  • Hydrophilicity: The presence of the chloride ion enhances solubility in aqueous solutions due to the increased attraction between the ion and water molecules.
  • Alkyl Chain Length: The attached alkyl groups can impact solubility; in this case, the chloroethyl groups may increase solubility in organic solvents in addition to water.

When considering practical applications, it’s noteworthy that:

  • The solubility of this compound in water allows for its potential use in biological systems.
  • It may be less soluble in non-polar solvents due to its ionic character.
  • Temperature can also play a role, as increasing heat often increases solubility for many ionic compounds.

In summary, the solubility of bis(2-chloroethyl)-[(5,6-dimethyl-1H-benzimidazol-2-yl)methyl]ammonium; chloride is primarily influenced by its ionic structure and interaction with various solvents, making it suitable for diverse applications in both aqueous and organic environments.

Interesting facts

Interesting Facts about Bis(2-chloroethyl)-[(5,6-dimethyl-1H-benzimidazol-2-yl)methyl]ammonium Chloride

Bis(2-chloroethyl)-[(5,6-dimethyl-1H-benzimidazol-2-yl)methyl]ammonium chloride is a fascinating compound with various implications in both medicinal chemistry and material science. Here are some intriguing points about this compound:

  • Medicinal Applications: This compound is often explored for its potential use in chemotherapy. The structure allows for specific interactions with cellular components, which can lead to effective treatments against cancer cells.
  • Dual Functionality: The bis(2-chloroethyl) moiety is known to provide alkylating properties, while the benzimidazole derivative enhances the compound's biological activity. This dual functionality makes it a subject of interest in the design of new drug candidates.
  • Chemical Stability: The presence of the 2-chloroethyl groups contributes to the stability and reactivity of the compound under various conditions, making it suitable for further research and application.
  • Pioneering Research: Compounds with similar structures have been pivotal in developing anti-tumor agents, sparking a wide range of studies aimed at understanding their mechanisms and improving their efficacy.

As researchers continue to delve into the properties of this compound, its multifaceted nature promises to yield valuable insights for future scientific endeavors. The synthesis of this compound involves complex methodologies that contribute to its intriguing profile, enhancing its appeal in both industrial and pharmaceutical fields.

In the words of one prominent chemist, “The exploration of new compounds often uncovers pathways to miraculous discoveries.” Bis(2-chloroethyl)-[(5,6-dimethyl-1H-benzimidazol-2-yl)methyl]ammonium chloride is a testament to this ethos.

Synonyms
Benzimidazole mustard
Dimethylbenzimidazole mustard
Benzimidazole methylene mustard
SKI 24482
CB 40042
Benzimidazole, 2-((bis(2-chloroethyl)amino)methyl)-5,6-dimethyl-, monohydrochloride
2-(Di-2-chloroethyl)aminomethyl-5,6-dimethylbenzimidazole
Benzimidazole, 2-((bis(2-chloroethyl)amino)methyl)-5,6-dimethyl-,
2-(Bis(2-chloroethyl)aminomethyl)-5,5-dimethylbenzimidazole hydrochloride
BENZIMIDAZOLE, 2-(BIS(2-CHLOROETHYL)AMINOMETHYL)-5,6-DIMETHYL-, HYDROCHLORIDE