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Bis(2-chloroethyl)-isopropyl-ammonium chloride

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Identification
Molecular formula
C8H18Cl2N
CAS number
55-91-4
IUPAC name
bis(2-chloroethyl)-isopropyl-ammonium;chloride
State
State

At room temperature, bis(2-chloroethyl)-isopropyl-ammonium chloride is primarily in the form of a solid. Its crystalline nature might give it a slightly opaque or translucent look, depending on the size of the crystals.

Melting point (Celsius)
70.50
Melting point (Kelvin)
343.65
Boiling point (Celsius)
250.00
Boiling point (Kelvin)
523.15
General information
Molecular weight
220.12g/mol
Molar mass
220.1200g/mol
Density
1.0800g/cm3
Appearence

Bis(2-chloroethyl)-isopropyl-ammonium chloride is typically found as a white crystalline solid. It can also appear as a powder depending on the specific formulation and handling. The compound is hygroscopic, meaning it can absorb moisture from the air, which can affect its appearance if not stored properly.

Comment on solubility

Solubility of bis(2-chloroethyl)-isopropyl-ammonium;chloride

The solubility of bis(2-chloroethyl)-isopropyl-ammonium;chloride can be influenced by various factors, primarily its ionic nature and the surrounding environment. As a quaternary ammonium salt, this compound typically exhibits the following characteristics regarding solubility:

  • Highly soluble in water: Due to its ionic character, this compound tends to dissolve well in polar solvents like water.
  • Varied solubility in organic solvents: Its solubility in non-polar organic solvents may be limited, thus favoring aqueous solutions.
  • Temperature dependence: Like many salts, solubility can increase with temperature, making heating a potential method for enhancing dissolution.

In practical applications, understanding the solubility of bis(2-chloroethyl)-isopropyl-ammonium;chloride ensures that it can be effectively utilized in formulations where it is needed, whether in aqueous environments or when considering phase interactions with other organic compounds. As noted, "the greater the ionic character, the higher the solubility in polar solvents", a principle that applies here.

Overall, careful attention to solvent choice and temperature conditions will yield the best results for this compound's solubility profile.

Interesting facts

Interesting Facts about Bis(2-Chloroethyl)-Isopropyl-Ammonium Chloride

Bis(2-chloroethyl)-isopropyl-ammonium chloride, often referred to in short as BCA, is a fascinating compound that finds utility in various fields, especially in medicinal chemistry and biology. Here are some intriguing points about this compound:

  • Quaternary Ammonium Compound: BCA is classified as a quaternary ammonium salt, which indicates the presence of a positively charged nitrogen atom bonded to four organic groups. This unique structure influences its biological and chemical properties.
  • Antimicrobial Properties: Compounds like BCA have been noted for their effective antimicrobial activities. Their ability to disrupt microbial membranes makes them valuable in disinfectants and antiseptic applications.
  • Pharmaceutical Applications: BCA is often utilized in drug formulations due to its compatibility and effectiveness with biological tissues. It may play a role in enhancing drug delivery systems, allowing for better absorption and efficacy in targeted therapies.
  • Reaction Characteristics: The presence of chloroethyl groups in BCA provides sites for further chemical modification. This can be useful in the synthesis of new pharmaceutical compounds, fostering innovation in drug development.
  • Historical Significance: Compounds similar to BCA were investigated during the mid-20th century for their potential as chemotherapeutic agents in cancer treatment, marking a significant period in medicinal chemistry research.

In summary, bis(2-chloroethyl)-isopropyl-ammonium chloride is more than just a chemical compound; it represents a nexus of chemistry and medicine, exhibiting properties that can lead to advancements in both fields. As researchers continue to explore its potential, BCA remains a captivating subject for study.

Synonyms
ISOPROPYLAMINE, N,N-BIS(2-CHLOROETHYL)-, HYDROCHLORIDE
24426-36-6
RefChem:1087684
Isopropyl bis(beta-chloroethyl)amine hydrochloride
TL 301 hydrochloride
Isopropyl-S hydrochloride
Diethylamine, 2,2'-dichloro-N-isopropyl-, hydrochloride
Triethylamine, 2,2'-dichloro-1''-methyl-, hydrochloride