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CYCLOPHOSPHAMIDE

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Identification
Molecular formula
C7H15Cl2N2O2P
CAS number
50-18-0
IUPAC name
bis(2-chloroethyl)amino-(3-hydroxypropylamino)phosphinic acid;cyclohexanamine
State
State
Cyclophosphamide is in a solid crystalline state at room temperature. It remains stable under typical room conditions if kept away from moisture and light.
Melting point (Celsius)
41.00
Melting point (Kelvin)
314.15
Boiling point (Celsius)
178.00
Boiling point (Kelvin)
451.15
General information
Molecular weight
261.09g/mol
Molar mass
261.0940g/mol
Density
1.4340g/cm3
Appearence

Cyclophosphamide is a white crystalline powder at room temperature. It is typically provided in the form of solid powder for medical and laboratory use, showing no distinct smell.

Comment on solubility

Solubility of bis(2-chloroethyl)amino-(3-hydroxypropylamino)phosphinic acid;cyclohexanamine

The solubility of bis(2-chloroethyl)amino-(3-hydroxypropylamino)phosphinic acid;cyclohexanamine is a complex topic due to its unique structure and the presence of multiple functional groups. Here are some important considerations regarding its solubility:

  • Compounds Presence: The compound contains both amine groups and an acidic phosphinic group, which can affect solubility in various solvents.
  • Polarity: Due to the presence of hydroxyl and amine functionalities, the compound is likely to be polar, enhancing solubility in polar solvents such as water.
  • Hydrogen Bonding: The potential for hydrogen bonding due to the -OH group may further increase its solubility in aqueous solutions.
  • Solvent Interactions: Additionally, in less polar solvents, the solubility could be diminished due to the hydrophobic carbocyclic structure of cyclohexanamine.
  • Temperature Effects: Temperature can also play a significant role; generally, increased temperature enhances the solubility of solids.

Ultimately, solubility can vary significantly depending on the solvent, concentration, and environmental conditions. The interplay of these factors means that experimental verification is typically necessary to determine the precise solubility characteristics. As highlighted by solubility principles, *"like dissolves like,"* indicating that the polarity of the solvent is a key parameter when predicting solubility behaviors.

Interesting facts

Interesting Facts about Bis(2-chloroethyl)amino-(3-hydroxypropylamino)phosphinic Acid;Cyclohexanamine

This compound boasts a complex structure that combines elements of both **phosphinic acid** and **amine chemistry**, making it a fascinating subject for researchers in medicinal chemistry. Here are some notable points to consider:

  • Dual Functionality: The presence of both the phosphinic acid and amine components may allow for various biological activities, including potential applications in pharmaceuticals.
  • Synthesis Challenges: Creating this compound could involve intricate synthetic pathways, making it an ideal case study in advanced organic synthesis courses.
  • Design Considerations: Its design reflects an interesting strategy in drug design where multiple functional groups are incorporated to enhance biological interactions.
  • Related Compounds: Research on phosphinic acid derivatives can lead to understanding their behavior as enzyme inhibitors, being important in medicinal chemistry and drug development.
  • Potential Applications: There is ongoing interest in investigating this compound for its possible uses in cancer therapy, reflecting how amines can be leveraged for therapeutic efficacy.

Researchers and students alike may find it intriguing how this compound exemplifies the intersection of **synthetic chemistry** and **biological functionality**. As articulated by one scientist, "The marriage of diverse functional groups in a single molecule opens avenues for innovation in treatment strategies." This makes studying compounds like bis(2-chloroethyl)amino-(3-hydroxypropylamino)phosphinic acid;cyclohexanamine not just an academic exercise, but a gateway to potential breakthroughs in medicine.

Synonyms
Cytoxyl alcohol cyclohexylamine salt
4465-94-5
NSC-52695
Cytoxyl alcohol cyclohexylammonium salt
Y1RVC1BHMC
cytoxal alcohol cyclohexylamine
Cytoxal alcohol cyclohexylamine salt
bis(2-chloroethyl)amino-(3-hydroxypropylamino)phosphinic acid;cyclohexanamine
CCRIS 6223
UNII-Y1RVC1BHMC
N,N-Bis(2-chloroethyl)-N'-(3-hydroxypropyl)phosphorodiamidate cyclohexylammonium salt
DTXSID5024893
N,N-Bis(2-chloroethyl)-N'-3-hydroxypropyl phosphorodiamidic acid
NSC52695
NSC 52695
Phosphorodiamidic acid, N,N-bis(2-chloroethyl)-N'-(3-hydroxypropyl)-, cyclohexylamine salt
Q27294151
N,N-bis(2-chloroethyl)-N'-(3-hydroxypropyl)phosphorodiamidic acid : cyclohexanamine (1:1)
Phosphorodiamidic acid,N-bis(2-chloroethyl)-N'-(3-hydroxypropyl)-, cyclohexylamine salt
Phosphorodiamidic acid,N-bis(2-chloroethyl)-N'-3-hydroxypropyl-, cyclohexylamine salt