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Bis(4-fluorophenyl)iodonium

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Identification
Molecular formula
C12H8FI
CAS number
045164-07-4
IUPAC name
bis(4-fluorophenyl)iodonium
State
State

At room temperature, Bis(4-fluorophenyl)iodonium exists as a solid. It is less commonly encountered in a liquid or gaseous state under normal conditions.

Melting point (Celsius)
192.00
Melting point (Kelvin)
465.15
Boiling point (Celsius)
215.00
Boiling point (Kelvin)
488.15
General information
Molecular weight
334.04g/mol
Molar mass
334.0430g/mol
Density
2.1243g/cm3
Appearence

Bis(4-fluorophenyl)iodonium is typically found as a crystalline solid. The compound is often colorless to pale yellow, depending on purity and form. It might also appear slightly off-white in some forms due to impurities or partial decomposition.

Comment on solubility

Solubility of bis(4-fluorophenyl)iodonium

The solubility of bis(4-fluorophenyl)iodonium can be quite intriguing. This compound is known for its unique chemical structure, which can affect its interaction with solvents. Understanding its solubility is essential for applications in organic synthesis and photochemistry. Here are some key points to consider:

  • Solvent Compatibility: bis(4-fluorophenyl)iodonium generally exhibits solubility in polar organic solvents such as DMSO and DMF. However, it tends to be less soluble in non-polar solvents.
  • Influence of Temperature: As with many organic compounds, increasing the temperature can enhance solubility, facilitating easier dissolution.
  • Solid Form: The crystalline form of bis(4-fluorophenyl)iodonium may affect its solubility; finer particles often dissolve more readily than larger ones.
  • Electrostatic Interactions: The presence of halogen atoms in its structure can create strong intermolecular forces, potentially impeding solubility in certain environments.

In conclusion, while bis(4-fluorophenyl)iodonium does have defined solubility characteristics, the interplay between its molecular structure and environmental factors makes it a captivating subject for further study. Understanding these dynamics allows chemists to tailor their applications effectively and optimize the use of this compound.

Interesting facts

Interesting Facts about bis(4-fluorophenyl)iodonium

bis(4-fluorophenyl)iodonium is a fascinating compound in the field of organic and medicinal chemistry. Its unique structure and properties make it a subject of significant interest. Here are some key points to consider:

  • Structure and Reactivity: The compound features an iodonium ion that is stabilized by two 4-fluorophenyl groups. This electron-withdrawing fluoro group enhances the electrophilic nature of the iodonium, making it a powerful reagent in various organic transformations.
  • Chemical Applications: Bis(4-fluorophenyl)iodonium is widely utilized in synthetic organic chemistry, particularly in nucleophilic substitutions, where it serves as an excellent source of electrophilic iodine.
  • Role in Photochemistry: This compound is also instrumental in photochemical reactions and can be used to generate radicals upon light irradiation, thus enabling controlled processes such as polymerization and cross-linking reactions.
  • Biological Significance: The potential pharmaceutical applications of iodonium compounds, including bis(4-fluorophenyl)iodonium, have attracted researchers due to their cytotoxic activity against certain cancer cells.
  • Research Interest: Scientists are constantly exploring the properties and reactivity of this compound, leading to new discoveries in the synthesis of advanced materials and drug development.

In summary, bis(4-fluorophenyl)iodonium is more than just an intriguing compound; it symbolizes the intersection of the fields of organic synthesis, medicinal chemistry, and material science, continuously inspiring researchers to delve deeper into its multifunctional applications.

Synonyms
SCHEMBL2464316