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4,4'-Difluorobenzophenone

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Identification
Molecular formula
C13H8F2O
CAS number
345-92-6
IUPAC name
bis(4-fluorophenyl)methanone
State
State

At room temperature, 4,4'-Difluorobenzophenone is in a solid state.

Melting point (Celsius)
47.00
Melting point (Kelvin)
320.15
Boiling point (Celsius)
284.00
Boiling point (Kelvin)
557.15
General information
Molecular weight
218.20g/mol
Molar mass
218.1980g/mol
Density
1.2650g/cm3
Appearence

4,4'-Difluorobenzophenone appears as a white to off-white crystalline powder. Its solid form is typically very fine, lending itself to various chemical reactions and applications in organic synthesis.

Comment on solubility

Solubility of bis(4-fluorophenyl)methanone

The solubility of bis(4-fluorophenyl)methanone, with the chemical formula C13H10F2O, can be understood by considering various factors that influence a compound's ability to dissolve in different solvents. Here are some key points regarding its solubility:

  • Polar vs. Non-polar Solvents: Due to its molecular structure, bis(4-fluorophenyl)methanone is likely to have limited solubility in polar solvents like water, while it may dissolve more readily in non-polar solvents such as hexane or toluene.
  • Hydrophobic Character: The presence of fluorine atoms contributes to the hydrophobic nature of the compound, making it less favorable for interactions with water molecules.
  • Temperature Effects: As with many organic compounds, solubility can increase with temperature, potentially allowing for better dissolution in organic solvents at elevated temperatures.
  • Concentration Factors: The concentration at which bis(4-fluorophenyl)methanone can reach saturation in a solvent can vary significantly, depending on the solvent used and its interactions with the compound.

Overall, while the solubility profile of bis(4-fluorophenyl)methanone indicates its preference for non-polar environments, understanding the solubility behavior can facilitate its effective use in various applications. As a general rule, compounds with similar polarities tend to dissolve well together, solidifying the saying, "like dissolves like."

Interesting facts

Interesting Facts about bis(4-fluorophenyl)methanone

bis(4-fluorophenyl)methanone, also known as 4-fluorobenzophenone, is a fascinating organic compound that falls under the category of ketones. Below are several interesting aspects that highlight its significance in the field of chemistry:

  • Structural Complexity: The compound features a unique structure characterized by the presence of two 4-fluorophenyl groups attached to a central carbonyl (C=O) group. This arrangement leads to interesting electronic properties and enhanced stability.
  • Applications in Industry: bis(4-fluorophenyl)methanone plays a critical role in the production of various pharmaceuticals and agrochemicals. Its derivatives can exhibit potent biological activities, making it a valuable building block in drug design.
  • Photochemical Properties: The compound can absorb UV light, which makes it useful in UV filters and stabilizers in plastics and coatings. Its ability to block harmful UV radiation is crucial for preserving the integrity of materials.
  • Analytical Significance: In analytical chemistry, bis(4-fluorophenyl)methanone can serve as a standard reference compound for techniques such as gas chromatography and mass spectrometry due to its well-defined molecular structure.
  • Reactivity: The compound is known for participating in various chemical reactions, such as Friedel-Crafts acylation and nucleophilic additions, which can lead to the synthesis of new and complex organic molecules.

In summary, bis(4-fluorophenyl)methanone is more than just a mere compound; it represents a gateway to understanding larger concepts in organic chemistry and catalysis. A quote often cited in synthetic organic chemistry sums it up well: "Chemistry is the art of manipulating matter to create new materials." This compound exemplifies that art in its diverse applications and functionalities.

Synonyms
4,4'-Difluorobenzophenone
345-92-6
Bis(4-fluorophenyl)methanone
bis(4-fluorophenyl)-methanone
Methanone, bis(4-fluorophenyl)-
Di-p-fluorophenyl ketone
p,p'-Difluorobenzophenone
Bis(p-fluorophenyl) ketone
Bis(4-fluorophenyl) ketone
MFCD00000353
NSC 51800
BENZOPHENONE, 4,4'-DIFLUORO-
EINECS 206-466-3
UNII-88BNC11B9C
BRN 0516231
88BNC11B9C
NSC-51800
4,4'-difluorodiphenylmethanone
DTXSID30188062
EC 206-466-3
4-07-00-01374 (Beilstein Handbook Reference)
p-fluorophenyl ketone
Dipfluorophenyl ketone
rho-Fluorophenyl Ketone
p,p'-Difluorbenzophenon
p,p'Difluorobenzophenone
Bis(pfluorophenyl) ketone
Bis(4fluorophenyl) ketone
WLN: FR DVR DF
4,4'-Diflourobenzophenone
Benzophenone,4'-difluoro-
Bis(4fluorophenyl)methanone
M-3-DFBP
4,4 '-difluorobenzophenone
Benzophenone, 4,4'difluoro
Methanone, bis(4fluorophenyl)
SCHEMBL238259
Bis-(4-fluoro-phenyl)methanone
DTXCID60110553
4,4'-Difluorobenzophenone, 99%
NSC51800
AKOS005063569
Methanone, bis(4fluorophenyl) (9CI)
CCG-245138
FD62650
Methanone, bis(4-fluorophenyl)-(9CI)
AC-10924
DB-014390
CS-0015469
D1797
NS00011109
4,4'-Difluorobenzophenone, analytical standard
D72510
EN300-118179
AE-848/31937058
Q4637051
4,4'-Difluorobenzophenone, TraceCERT(R), certified reference material, 19F-qNMR Standard