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Butane-1-sulfonamide

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Identification
Molecular formula
C4H11NO2S
CAS number
4740-01-8
IUPAC name
butane-1-sulfonamide
State
State

At room temperature, butane-1-sulfonamide is a solid.

Melting point (Celsius)
162.00
Melting point (Kelvin)
435.15
Boiling point (Celsius)
268.80
Boiling point (Kelvin)
541.95
General information
Molecular weight
121.20g/mol
Molar mass
121.1940g/mol
Density
1.1095g/cm3
Appearence
Butane-1-sulfonamide typically appears as a white crystalline solid.
Comment on solubility

Solubility of Butane-1-sulfonamide

Butane-1-sulfonamide, with the chemical formula C4H9NO2S, showcases interesting solubility characteristics that can be attributed to its molecular structure and functional groups.

Key Solubility Insights:

  • Polar Nature: The presence of the sulfonamide group (-SO2NH2) imparts a degree of polarity to the molecule, enhancing its solubility in polar solvents.
  • Water Solubility: Butane-1-sulfonamide is generally considered to be soluble in water, owing to hydrogen bonding interactions between the sulfonamide functional group and water molecules.
  • Organic Solvents: It is also soluble in various organic solvents such as methanol and ethanol, further showcasing its versatile solubility profile.
  • Temperature Dependence: It’s worth noting that solubility can be temperature-dependent, often increasing with higher temperatures, which is a common trait among many chemical compounds.

In summary, the solubility of butane-1-sulfonamide displays a favorable profile in both polar and some organic solvents, making it a compound of interest in various chemical applications. Overall, understanding its solubility behavior not only aids in practical handling but also informs its reactivity and use in synthesis.

Interesting facts

Interesting Facts About Butane-1-sulfonamide

Butane-1-sulfonamide is a fascinating compound that falls under the category of sulfonamides, which are well-known in the fields of chemistry and pharmaceuticals. Here are some compelling aspects of this compound:

  • Pharmaceutical Applications: Sulfonamides, including butane-1-sulfonamide, have historically played a significant role in medicine. They were among the first antibiotics and continue to be essential in the development of various pharmaceutical drugs.
  • Chemical Structure: The presence of the sulfonamide group is pivotal for its reactivity. This feature can enhance the compound's solubility and ability to form complexes with other molecules, which is crucial in medicinal chemistry.
  • Role in Organic Synthesis: Butane-1-sulfonamide is utilized as a building block in organic synthesis, helping chemists create a variety of pharmaceuticals, agrochemicals, and other chemical compounds.
  • Environmental Impact: Understanding the behavior of sulfonamides in the environment is vital. Studies have shown that they can persist in various ecosystems, leading to ongoing research into their ecological effects and degradation pathways.

In the words of a notable chemist, “The beauty of chemistry lies in its ability to create a bridge between our understanding of molecular interactions and practical applications in medicine and industry.” Butane-1-sulfonamide exemplifies this connection, demonstrating how a simple molecular change can lead to significant advancements in health and technology.

Overall, the study of butane-1-sulfonamide not only reflects its individual properties but also embodies the wider implications of sulfonamides in scientific research, development, and application.

Synonyms
butane-1-sulfonamide
1-BUTANESULFONAMIDE
3144-04-5
butanesulfonamide
Butansulfamid
Butansulfamid [German]
NSC 26772
BRN 1749709
DTXSID80185364
DTXCID90107855
674-861-1
N-Butylsulfonamide
934CE25MDC
NSC-26772
n-butylsulphonamide
MFCD00465180
1-n-Butanesulfonamide
SCHEMBL2826
Butan-1-sulfonic acid amide
UNII-934CE25MDC
butane-1-sulfonic acid amide
OVIZSQRQYWEGON-UHFFFAOYSA-N
NSC26772
AKOS000143030
FS-4925
DB-068463
CS-0450901
EN300-30817
Z55264566