Skip to main content

Butyl Nicotinate

ADVERTISEMENT
Identification
Molecular formula
C11H17NO2
CAS number
2226-78-6
IUPAC name
butyl 1-methyl-3,6-dihydro-2H-pyridine-5-carboxylate
State
State
Liquid at room temperature, with a somewhat viscous consistency. It is often utilized in various industrial and cosmetic applications due to its beneficial properties.
Melting point (Celsius)
-20.00
Melting point (Kelvin)
253.15
Boiling point (Celsius)
135.00
Boiling point (Kelvin)
408.15
General information
Molecular weight
193.26g/mol
Molar mass
193.2590g/mol
Density
0.9861g/cm3
Appearence

Butyl Nicotinate is typically a colorless to pale yellow liquid. It has an oily consistency and is often used in cosmetic formulations due to its skin conditioning properties. The liquid is noted for its characteristic ester-like odor.

Comment on solubility

Solubility of Butyl 1-Methyl-3,6-Dihydro-2H-Pyridine-5-Carboxylate

When exploring the solubility of butyl 1-methyl-3,6-dihydro-2H-pyridine-5-carboxylate, it’s important to consider various factors that affect its behavior in different solvents. This compound has several key characteristics that influence its solubility:

  • Solvent Polarity: The solubility of this compound tends to be higher in polar organic solvents due to its functional groups, which can interact well with similar solvent molecules.
  • Temperature Effects: An increase in temperature typically enhances solubility as molecular motion increases, allowing for better interaction between solute and solvent.
  • Functional Group Interaction: The presence of carboxylate groups may enable hydrogen bonding with solvents, thereby improving solubility in aqueous solutions albeit the overall structure suggests preferential solubility in organic solvents.
  • Chain Length Impact: The butyl group in its structure contributes to hydrophobic characteristics; thus, the compound is less soluble in water but more favorable in nonpolar solvents.

In summary, while butyl 1-methyl-3,6-dihydro-2H-pyridine-5-carboxylate displays modulated solubility based on its interactions with solvents, it is essential to select the solvent environment carefully. As the general rule states, "like dissolves like," so utilizing polar solvents will yield different solubility profiles compared to nonpolar solvents.

Interesting facts

Interesting Facts about Butyl 1-Methyl-3,6-Dihydro-2H-Pyridine-5-Carboxylate

Butyl 1-methyl-3,6-dihydro-2H-pyridine-5-carboxylate is an intriguing compound that belongs to the class of pyridine derivatives. Here are some interesting aspects worth noting:

Chemical Structure and Applications

This compound features a unique structure that includes:

  • A pyridine ring, which is known for its aromatic properties.
  • A carboxylate functional group, contributing to its reactivity.
  • A butyl side chain, which enhances its solubility in organic solvents.

Such structural features make it valuable in various applications, including:

  • As a precursor in the synthesis of pharmaceutical compounds.
  • In agrochemicals, particularly for designing herbicides.
  • As a building block in materials science for developing novel polymers.

Biological Relevance

Interestingly, compounds similar to butyl 1-methyl-3,6-dihydro-2H-pyridine-5-carboxylate have been observed to exhibit:

  • Antimicrobial activity: They may hinder the growth of certain bacteria and fungi.
  • Neuroprotective effects: Some derivatives impact neurotransmitter systems in the brain.

These biological properties underscore the importance of studying pyridine derivatives for potential therapeutic uses.

Research and Development

Ongoing research focuses on:

  • Understanding the mechanisms behind its biological activity.
  • Exploring modifications to enhance its efficacy and reduce potential toxicity.
  • The development of sustainable synthesis methods to minimize environmental impact.

As scientists continue to explore butyl 1-methyl-3,6-dihydro-2H-pyridine-5-carboxylate, its applications may expand, paving the way for new discoveries in both medicinal and agricultural chemistry.

In conclusion, this compound exemplifies the fascinating interplay between chemical structure and biological function, making it a worthy subject of study for both chemistry students and seasoned scientists alike.

Synonyms
n-Butyl-1-methyl-1,2,5,6-tetrahydronicotinate
5497-45-0
BRN 0136369
NICOTINIC ACID, 1,2,5,6-TETRAHYDRO-1-METHYL-, BUTYL ESTER
DTXSID70203501
DTXCID30125992
5-22-01-00323 (beilstein handbook reference)