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Metformin hydrochloride

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Identification
Molecular formula
C4H12N5Cl
CAS number
1115-70-4
IUPAC name
carbamimidoyl-[N'-[4-(dimethylcarbamoyl)phenyl]carbamimidoyl]ammonium;chloride
State
State

At room temperature, metformin hydrochloride is in a solid state, specifically a crystalline powder.

Melting point (Celsius)
223.00
Melting point (Kelvin)
496.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
165.63g/mol
Molar mass
165.6250g/mol
Density
1.3400g/cm3
Appearence

Metformin hydrochloride appears as a white to off-white, crystalline powder. It is odorless and hygroscopic, and it is freely soluble in water, slightly soluble in ethanol (95%), and practically insoluble in acetone and methylene chloride.

Comment on solubility

Solubility of Carbamimidoyl-[N'-[4-(dimethylcarbamoyl)phenyl]carbamimidoyl]ammonium Chloride

Carbamimidoyl-[N'-[4-(dimethylcarbamoyl)phenyl]carbamimidoyl]ammonium chloride is a compound that presents unique solubility characteristics, largely influenced by its molecular structure and functional groups.

  • Polar Nature: The presence of multiple nitrogen atoms and the ammonium group contributes to a more polar character, enhancing its solubility in polar solvents, particularly water.
  • Hydrophilic Interactions: The chloride anion further facilitates solubility through ionic interactions with water molecules, making it readily soluble in aqueous solutions.
  • Solvent Variability: Solubility may vary significantly in organic solvents; it is often less soluble in non-polar solvents due to the lack of compatible interactions.

In summary, the solubility of this compound can be described as:

  1. High solubility in water, thanks to its ionic nature.
  2. Limited solubility in non-polar organic solvents, which reflects typical behavior for polar compounds.

Understanding these solubility properties can be essential for applications in various chemical and pharmaceutical contexts, where solvent choice is crucial for effective functionality.

Interesting facts

Interesting Facts about Carbamimidoyl-[N'-[4-(dimethylcarbamoyl)phenyl]carbamimidoyl]ammonium; Chloride

This unique compound, known for its complex structure, offers a plethora of fascinating attributes that are worthy of exploration:

  • Pharmacological Potential: Compounds containing ammonium and carbamimidoyl groups are often evaluated for their potential pharmacological activities. Research has indicated that similar compounds may exhibit properties such as anti-inflammatory and anti-cancer effects.
  • Structure-Activity Relationship: The presence of aromatic rings, like phenyl groups in this compound, often influences its reactivity and biological activity, making it a subject of interest in medicinal chemistry.
  • Applications in Organic Synthesis: Due to its functional groups, this compound may serve as a versatile building block in organic synthesis, particularly in the creation of more complex molecules.
  • Ion Exchange: The chloride component suggests potential roles in ion exchange processes, which are pivotal in fields such as materials science and catalysis.

Moreover, as a compound that entails multiple nitrogen atoms, it showcases the versatility of nitrogen-rich compounds in synthetic and analytical chemistry. The study of such compounds often leads to exciting new discoveries as chemists delve into their reactivity and biological implications.

As with many advanced organic compounds, the path to understanding its full potential involves meticulous research and experimentation, often yielding groundbreaking insights in both theoretical and applied chemistry. "Science knows no bounds; it is not constrained by the limits of our imagination."

Synonyms
BENZAMIDE, p-(3-AMIDINOGUANIDINO)-N,N-DIMETHYL-, MONOHYDROCHLORIDE
p-(3-Amidinoguanidino)-N,N-dimethylbenzamide monohydrochloride
4751-83-1
DTXSID30197174
DTXCID40119665