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Citric acid

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Identification
Molecular formula
C6H8O7
CAS number
77-92-9
IUPAC name
citric acid;N-ethyl-3-phenyl-N-(3-phenylpropyl)propan-1-amine
State
State

At room temperature, citric acid is a solid. It is generally found in a crystalline or granulated form.

Melting point (Celsius)
153.00
Melting point (Kelvin)
426.15
Boiling point (Celsius)
310.00
Boiling point (Kelvin)
583.15
General information
Molecular weight
192.12g/mol
Molar mass
192.1240g/mol
Density
1.6650g/cm3
Appearence

Citric acid appears as a colorless crystalline solid. It is commonly found in a powder or granular form and is highly soluble in water. It has a distinctly sour taste and is a natural preservative/conservative often found in citrus fruit juices.

Comment on solubility

Solubility of Citric Acid

Citric acid, with the chemical formula C6H8O7, is a well-known organic acid that plays a key role in various biochemical processes. Its solubility properties are quite remarkable:

  • Highly Soluble in Water: Citric acid is strongly soluble in water, which allows it to easily dissociate into its ions, making it effective in various applications.
  • Temperature Dependency: The solubility of citric acid increases with temperature, so it is more soluble in hot water compared to cold water.
  • Common Solvent: This compound is often used in food and beverage industries for flavoring and preservation, thanks to its solubility.

Its high solubility is attributed to the presence of multiple carboxylic acid groups, which can form hydrogen bonds with water molecules, enhancing its dissolution properties.


Solubility of N-ethyl-3-phenyl-N-(3-phenylpropyl)propan-1-amine

N-ethyl-3-phenyl-N-(3-phenylpropyl)propan-1-amine, having a more complex structure, possesses different solubility characteristics:

  • Solubility Varied by Solvent: This compound shows variable solubility depending on the solvent used, tending to dissolve better in organic solvents compared to water.
  • Hydrophobic Nature: Due to its hydrophobic phenyl groups, this substance is likely to have low solubility in polar solvents like water.
  • Potential Use in Non-Aqueous Systems: Given its solubility characteristics, it might be utilized effectively in non-aqueous environments for various chemical applications.

Understanding the solubility of such compounds is critical, as it can influence their reactivity, availability in biological systems, and efficacy in various applications.

Interesting facts

Exploring Citric Acid

Citric acid is a fascinating organic compound that plays a crucial role in both biochemistry and various industries. Here are some engaging facts about this versatile compound:

  • Biological Importance: Citric acid is a key player in the citric acid cycle, also known as the Krebs cycle, which is fundamental for cellular respiration in living organisms.
  • Citrus Fruits: The compound was first isolated from lemon juice in the mid-18th century and is found abundantly in citrus fruits. Its refreshing taste makes it a popular choice in food and drink.
  • Preservative Properties: Citric acid acts as a natural preservative and is commonly used to enhance flavor and prevent browning in various food products.
  • pH Control: It is an excellent acidulant that helps maintain the desired acidity levels in foods and beverages, ensuring consistency and stability.
  • Industrial Applications: Beyond food, citric acid is extensively used in cosmetics, pharmaceuticals, and cleaning agents due to its antioxidant properties and ability to chelate metals.

Overall, citric acid is a multifunctional compound that not only enhances our culinary experiences but also supports various industrial applications and biological processes. Its wide-ranging uses highlight the interconnectedness of chemistry and daily life.


The Unique Structure of N-ethyl-3-phenyl-N-(3-phenylpropyl)propan-1-amine

N-ethyl-3-phenyl-N-(3-phenylpropyl)propan-1-amine is a complex compound that belongs to a category of organic molecules known as amines. Here are several notable aspects of this compound:

  • Structural Complexity: This amine features a branched structure that can lead to interesting steric and electronic effects, which can influence its reactivity and interactions with other molecules.
  • Pharmacological Potential: The presence of aryl groups (phenyl) suggests that this compound could exhibit significant biological activity, and similar structures are often studied for their potential therapeutic effects.
  • Research Applications: Compounds like N-ethyl-3-phenyl-N-(3-phenylpropyl)propan-1-amine are often explored in medicinal chemistry to develop new drugs or understanding ligand-receptor interactions.
  • Variability of Properties: The presence of the ethyl group and the phenyl groups may add to the compound's hydrophobic character, influencing its solubility and behavior in biological systems.

Despite its complex name, N-ethyl-3-phenyl-N-(3-phenylpropyl)propan-1-amine exemplifies the diversity within organic chemistry, inviting researchers to explore its potential and implications in various scientific fields.

Synonyms
ALVERINE CITRATE
5560-59-8
Antispasmin
Spacolin
Gamatran citrate
Spasmaverine
NSC 35459
Calmabel
Profenine
Prophelan
Proverine
Profenil citrate
NCI 85x
Spasmonal
Alverine citrate [USAN]
UNII-9JFB58YK1E
PHENPROPAMINE CITRATE
9JFB58YK1E
NSC-35459
Alverine citrate [USAN:NF]
DTXSID3045562
N-Ethyl-3,3'-diphenyldipropylamine citrate (1:1)
CHEBI:53785
Alverine citrate (USAN)
EINECS 226-929-3
ALVERINE CITRATE [MI]
Dipropylamine, N-ethyl-3,3'-diphenyl-, citrate (1:1)
N-Ethyl-3,3'-diphenyldipropylamine citrate
N-ethyl-3-phenyl-N-(3-phenylpropyl)propan-1-amine 2-hydroxypropane-1,2,3-tricarboxylate
DTXCID1025562
ALVERINE CITRATE [MART.]
ALVERINE CITRATE [WHO-DD]
Dipropylamine, N-ethyl-3,3'-diphenyl-, citrate
N-Ethyl-bis(3-phenylpropyl)amin-dihydrogencitrat
Benzenepropanamine, N-ethyl-N-(3-phenylpropyl)-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1)
ALVERINE CITRATE [EP MONOGRAPH]
ALVERINE CITRATE (MART.)
ALVERINE CITRATE (EP MONOGRAPH)
Audmonal
Gielism
Spasmonal fte
Dipropylamine, N-ethyl-3,3'-diphenyl-, citrate (1:1) (8CI)
226-929-3
Benzenepropanamine, N-ethyl-N-(3-phenylpropyl)-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1) (9CI)
Alverine (citrate)
ALVERINE CITRATE SALT
MLS000069524
5560-59-8 (citrate)
NCGC00017047-01
SMR000058631
CAS-5560-59-8
1346604-63-4
N-(Ethyl-d5)-4-methoxy Amphetamine Hydrochloride
SR-01000003029
Alverine dihydrogen citrate
N-(Ethy-d5)l-4-methoxy-a-methylbenzeneethanamine Hydrochloride; (+/-)-N-(Ethyl-d5)-p-methoxyamphetamine Hydrochloride; 2-(Ethyl-d5)amino-1-(4'-methoxyphenyl)propane Hydrochloride; N-(Ethyl-d5)-p-methoxy-a-methylphenethylamine Hydrochloride;
Prestwick_912
ALVERINECITRATE
Opera_ID_1477
MLS001148462
MLS002207301
MLS002222279
MLS004712036
SCHEMBL352008
SPECTRUM1500109
REGID_for_CID_21718
Alverine (citrate) (Standard)
CHEMBL1408594
HY-B0500R
RYHCACJBKCOBTJ-UHFFFAOYSA-N
GLXC-05122
HMS1568D09
HMS1920A17
HMS2091G17
HMS2095D09
HMS2232D03
HMS3371I14
HMS3651F18
HMS3712D09
HMS3885O05
Pharmakon1600-01500109
HY-B0500
QYB32700
Tox21_110757
Dipropylamine,3'-diphenyl-, citrate
MFCD00035086
NSC755859
s3054
AKOS015895657
Tox21_110757_1
CCG-212472
FE17335
NSC-755859
NCGC00017047-02
NCGC00017047-03
NCGC00021122-08
NCGC00094581-01
NCGC00094581-02
AS-56723
DB-052764
A2896
Dipropylamine,3'-diphenyl-, citrate (1:1)
NS00080869
SW197030-3
D02877
D84224
SR-01000003029-2
SR-01000003029-4
Q27124210
Benzenepropanamine, 2-hydroxy-1,2,3-propanetricarboxylate (1:1)
2-hydroxypropane-1,2,3-tricarboxylic acid; ethylbis(3-phenylpropyl)amine
Alverine citrate salt, European Pharmacopoeia (EP) Reference Standard
Alverine for peak identification, European Pharmacopoeia (EP) Reference Standard
N-Ethyl-N-(3-phenylpropyl)benzenepropanamine 2-hydroxy-1,2,3-propanetricarboxylate;N-Ethyl-3,3'-diphenyldipropylamine citrate;Antisp asmin;Alverine citrate