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Citric acid

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Identification
Molecular formula
C6H8O7
CAS number
77-92-9
IUPAC name
citric acid;N,N-diethyl-4-methyl-piperazine-1-carboxamide
State
State

At room temperature, citric acid is in a solid state.

Melting point (Celsius)
153.00
Melting point (Kelvin)
426.15
Boiling point (Celsius)
310.00
Boiling point (Kelvin)
583.15
General information
Molecular weight
192.12g/mol
Molar mass
192.1240g/mol
Density
1.6650g/cm3
Appearence

Citric acid is a white crystalline solid. It is often found in a fine granular form in its anhydrous state, while the monohydrate form can appear slightly more translucent. It is soluble in water and has a tart taste, characteristic of citrus fruits.

Comment on solubility

Solubility of Citric Acid

Citric acid, with the chemical formula C6H8O7, is highly soluble in water. This characteristic is largely due to its multiple carboxyl groups that can engage in hydrogen bonding with water molecules. Here are some notable points regarding its solubility:

  • Acidic Nature: Citric acid is a triprotic acid, meaning it can donate three protons (H+) in solution, which enhances its interactions with water.
  • Temperature Dependency: Solubility increases with temperature, providing greater dispersion in warm solutions.
  • Solvent Compatibility: While it is highly soluble in polar solvents like water, its solubility in non-polar solvents is negligible.

In terms of industrial applications, its solubility makes citric acid useful in food preservation, flavoring, and as an acidity regulator.

Solubility of N,N-Diethyl-4-methyl-piperazine-1-carboxamide

N,N-Diethyl-4-methyl-piperazine-1-carboxamide, represented by the formula C12H22N2O, exhibits a moderate solubility in water. The solubility characteristics can be summarized as follows:

  • Amine Functionality: The amine groups in the piperazine ring may facilitate some level of interaction with water molecules, contributing to its solubility.
  • Hydrophobic Tail: The presence of the ethyl groups introduces hydrophobic characteristics, which can reduce overall solubility compared to more polar compounds.
  • Solvent Specificity: It tends to be more soluble in organic solvents, indicating that its solubility is influenced by solvent polarity.

Understanding the solubility of N,N-diethyl-4-methyl-piperazine-1-carboxamide is essential for its application in chemical formulations.

Interesting facts

Interesting Facts about Citric Acid

Citric acid is a fascinating organic compound that plays a crucial role in biochemistry and everyday life. As a natural preservative and flavoring agent, it is found in a variety of foods, especially fruits such as lemons and limes.

Here are some noteworthy points about citric acid:

  • Metabolic Pathway: Citric acid is a key intermediate in the citric acid cycle (also known as the Krebs cycle), a fundamental pathway for energy production in all aerobic organisms.
  • Chelating Agent: Its ability to bind metals and act as a chelating agent makes citric acid useful in various applications, including cleaning agents and food preservation.
  • Health Benefits: Citric acid can assist in improving the absorption of minerals, aiding in kidney stone prevention, and even enhancing metabolism when consumed.
  • Industrial Uses: Beyond food applications, citric acid is extensively used in cosmetics, pharmaceuticals, and in the manufacturing of biodegradable plastics.

As a testament to its significance, citric acid is considered GRAS (Generally Recognized as Safe) by the FDA, highlighting its wide acceptance in various industries.

Exploring N,N-Diethyl-4-methyl-piperazine-1-carboxamide

N,N-Diethyl-4-methyl-piperazine-1-carboxamide, also known by its more informal name, is a lesser-known compound in the realm of organic chemistry, yet it holds interesting potential.

Here are some key points regarding this compound:

  • Chemical Structure: This compound features a piperazine ring, which is significant in medicinal chemistry for its applications in pharmaceutical compounds.
  • Potential Uses: The carboxamide functional group contributes to its potential role as a building block in drug synthesis and could exhibit interesting biological properties.
  • Toxicological Considerations: As with many synthetic compounds, understanding its safety profile and toxicological data is crucial for evaluating its practical applications.
  • Synthesis Variability: The synthesis of this compound can vary, and exploring different synthetic pathways can lead to the discovery of related molecules with enhanced properties.

In conclusion, while not as widely recognized as citric acid, N,N-diethyl-4-methyl-piperazine-1-carboxamide presents an exciting area for further research in organic synthesis and potential pharmaceutical applications.

Synonyms
DIETHYLCARBAMAZINE CITRATE
1642-54-2
Dicarocide
Banocide
Caritrol
Eosinopin
Filazine
Franocide
Franozan
Carbam Palatabs
Ditrazin citrate
Ethodryl citrate
Diro-Form
DEC Chewable
Dek-Tabs
Dirocide
Ditrazine
Ditrazinum
Filarabits
Longicid
Ditrazini citras
Carricide citrate
Ditrazine citrate
Diethylcarbamazane citrate
D.E.C. Sol
Diethylcarbamazine acid citrate
Diethylcarbamazini citras
Diethylcarbamazine hydrogen citrate
Ethylaminoazine citrate
HSDB 6421
N,N-Diethyl-4-methyl-1-piperazinecarboxamide citrate
EINECS 216-696-6
1-Methyl-4-diethylcarbamoylpiperazine citrate
UNII-OS1Z389K8S
NSC 80513
NSC-80513
OS1Z389K8S
DTXSID4045555
1-Diethylcarbamoyl-4-methylpiperazine dihydrogen citrate
N,N-Diethyl-4-methyl-1-piperazinecarboxamide citrate (1:1)
N,N-Diethyl-4-methyl-1-piperazinecarboxamide dihydrogen citrate
N,N-Diethyl-4-methyl-1-piperazine carboxamide citrate
1-Piperazinecarboxamide, N,N-diethyl-4-methyl-, citrate
1-Piperazinecarboxamide, N,N-diethyl-4-methyl-, 2-hydroxy-1,2,3-propanetricarboxylate
DTXCID2025555
1-Piperazinecarboxamide, N,N-diethyl-4-methyl-, citrate (1:1)
N,N-Diethyl-4-methyl-1-piperazinecarboxamide dihydrogen citrate (1:1)
Diethylcarbamazine citrate [USP:JAN]
Diethylcarbamazine citrate (USP:JAN)
DIETHYLCARBAMAZINE CITRATE (MART.)
DIETHYLCARBAMAZINE CITRATE [MART.]
DIETHYLCARBAMAZINE CITRATE (USP-RS)
DIETHYLCARBAMAZINE CITRATE [USP-RS]
DIETHYLCARBAMAZINE CITRATE (USP IMPURITY)
DIETHYLCARBAMAZINE CITRATE [USP IMPURITY]
DIETHYLCARBAMAZINE CITRATE (USP MONOGRAPH)
DIETHYLCARBAMAZINE CITRATE [USP MONOGRAPH]
Carbam Tablets
Dirocide Syrup
Filban Tablets
Dirocide Tablets
Pet-Dec
Nemacide Oral Syrup
DITRAZIN
Nemacide, Nemacide-C
Filban Chewable Wafers
Nemacide Chewable Tablets
Citrate, Diethylcarbamazine
Filaribits Chewable Tablets
Diethylcarbamazine Citrate Tab., Diro-Form
N,N-Diethyl-4-methylpiperazine-1-carboxamide monocitrate
N,N-Diethyl-4-methylpiperazine-1-carboxamide dihydrogen citrate
1-PIPERAZINECARBOXAMIDE, N,N-DIETHYL-4-METHYL-, CITRATE(1:1)
1-PIPERAZINECARBOXAMIDE, N,N-DIETHYL-4-METHYL-, 2-HYDROXY-1,2,3-PROPANETRI-CARBOXYLATE
216-696-6
rp 3799
Hetrazan
Loxuran
Diethylcarbamazine (citrate)
Diethylcarbamazine dihydrogen citrate
Diethylcarbamazine citrate salt
MFCD00039124
MLS000069762
MLS001074102
N,N-diethyl-4-methylpiperazine-1-carboxamide;2-hydroxypropane-1,2,3-tricarboxylic acid
NCGC00017034-01
SMR000058650
CAS-1642-54-2
N,N-Diethyl-4-methylpiperazine-1-carboxamide 2-hydroxypropane-1,2,3-tricarboxylate
1642-54-1(citrate); 90-89-1(free base)
N,N-diethyl-4-methylpiperazine-1-carboxamide citrate
16354-46-4
SR-01000759234
Hetrazan (TN)
Prestwick_166
Opera_ID_558
CHEMBL937
1-Piperazinecarboxamide, N,N-diethyl-4-methyl-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1)
SCHEMBL37736
MLS002207116
MLS004773909
SPECTRUM1500242
CHEBI:4528
HMS501L10
PGNKBEARDDELNB-UHFFFAOYSA-N
HMS1568J10
HMS1920G06
HMS2091M16
HMS2095J10
HMS2234D17
HMS3370G20
HMS3712J10
Pharmakon1600-01500242
Tox21_110748
CCG-40067
HY-12642R
NSC152050
NSC756735
s4564
AKOS003390253
Tox21_110748_1
CS-3871
Diethylcarbamazine citrate (JP17/USP)
DIETHYLCARBAMAZINE CITRATE [MI]
NSC-152050
NSC-756735
Diethylcarbamazine (citrate) (Standard)
DIETHYLCARBAMAZINE CITRATE [JAN]
DIETHYLCARBAMAZINE CITRATE [HSDB]
NCGC00017034-02
NCGC00017034-03
NCGC00090954-07
NCGC00094651-01
NCGC00094651-02
BS-15595
HY-12642
DIETHYLCARBAMAZINE CITRATE [WHO-DD]
DB-043586
D1898
NS00076312
C73172
D00803
DIETHYLCARBAMAZINE CITRATE [GREEN BOOK]
DIETHYLCARBAMAZINE CITRATE [ORANGE BOOK]
WLN: T6N DNTJ AVN2&2 D1 &OV1XQVO&1VO
SR-01000759234-2
SR-01000759234-4
DIETHYLCARBAMAZINE DIHYDROGEN CITRATE [WHO-IP]
Q27285812
DIETHYLCARBAMAZINI DIHYDROGENOCITRAS [WHO-IP LATIN]
N,N-Diethyl-4-methyl-1-piperazinecarboxamide citrate salt
1-Piperazinecarboxamide,N-diethyl-4-methyl-, citrate (1:1)
Diethylcarbamazine citrate salt, VETRANAL(TM), analytical standard
Diethylcarbamazine citrate, British Pharmacopoeia (BP) Reference Standard
Diethylcarbamazine citrate, European Pharmacopoeia (EP) Reference Standard
1-Piperazinecarboxamide,N-diethyl-4-methyl-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1)
Diethylcarbamazine citrate, United States Pharmacopeia (USP) Reference Standard