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Copper protoporphyrin IX

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Identification
Molecular formula
C34H34CuN4O5
CAS number
14075-90-2
IUPAC name
copper;3-[18-(2-carboxyethyl)-7,12-bis(1-hydroxyethyl)-3,8,13,17-tetramethyl-porphyrin-21,23-diid-2-yl]propanoic acid
State
State

At room temperature, copper protoporphyrin IX is in a solid state. It is often used in biochemical and medical applications related to its role as a heme metabolism intermediate.

Melting point (Celsius)
320.00
Melting point (Kelvin)
593.15
Boiling point (Celsius)
780.00
Boiling point (Kelvin)
1 053.15
General information
Molecular weight
679.00g/mol
Molar mass
678.9970g/mol
Density
1.0900g/cm3
Appearence

Copper protoporphyrin IX typically appears as a dark green powder. This color is attributed to the copper ion coordinated within the porphyrin ring, giving it a distinct appearance compared to other protoporphyrins.

Comment on solubility

Solubility of Copper;3-[18-(2-carboxyethyl)-7,12-bis(1-hydroxyethyl)-3,8,13,17-tetramethyl-porphyrin-21,23-diid-2-yl]propanoic acid

The solubility of copper;3-[18-(2-carboxyethyl)-7,12-bis(1-hydroxyethyl)-3,8,13,17-tetramethyl-porphyrin-21,23-diid-2-yl]propanoic acid can be quite intricate due to its complex molecular structure. Generally, the solubility behavior of this compound can be influenced by several factors:

  • Polarity: The presence of multiple functional groups, including carboxylic acids and hydroxyls, suggests that this compound may exhibit significant polarity, enhancing its solubility in polar solvents such as water.
  • Hydrophilicity vs. Hydrophobicity: The balance between hydrophobic (non-polar) and hydrophilic (polar) segments within the molecule plays a crucial role. The carboxyethyl groups are typically hydrophilic, while the porphyrin structure may present hydrophobic characteristics.
  • Concentration of Solvent: In aqueous solutions, increased temperature may enhance solubility, but the specific solubility limits can vary significantly based on concentration.
  • pH Sensitivity: The solubility may be affected by the pH of the solution, as altering the protonation state of the carboxyl groups can greatly influence solubility properties.

As a general guideline:

  1. At low pH, the carboxylic acid groups may remain protonated, potentially leading to lower solubility.
  2. At neutral to high pH, deprotonation can result in increased solubility due to enhanced ionic interactions.

To summarize, while this compound shows promise for solubility in polar solvents, specific conditions should be explored analytically due to its intricate structure and varying interactions. Understanding these factors can significantly aid in practical applications of this compound.

Interesting facts

Interesting Facts about Copper; 3-[18-(2-carboxyethyl)-7,12-bis(1-hydroxyethyl)-3,8,13,17-tetramethyl-porphyrin-21,23-diid-2-yl]propanoic Acid

This fascinating compound is a chelated form of copper that plays a significant role in various biochemical processes. Copper(II) complexes, especially porphyrins, have been extensively studied for their unique properties and functionalities, making them crucial in catalysis and medicinal chemistry.

Key Highlights:

  • Biological significance: Copper is an essential trace element in biological systems, vital for enzymatic reactions and the maintenance of overall health.
  • Role in catalysis: This compound participates in redox reactions, making it a valuable catalyst in organic synthesis, particularly in oxidation processes.
  • Potential therapeutic applications: Some copper porphyrins show promise as therapeutic agents, particularly in the treatment of cancer and other diseases due to their ability to mimic natural biological processes.
  • Light absorption: The porphyrin structure allows this compound to absorb light efficiently, which can be harnessed for photodynamic therapy, a method used to destroy cancer cells using light-activated drugs.
  • Structure and stability: The intricate design of the porphyrin ring in this compound contributes to its stability and facilitates the binding of metal ions, which is essential for its functionality.

As chemists continue to explore the properties of this copper complex, it opens up new avenues for research, notably in fields like materials science, biochemistry, and pharmacology. The versatility of copper porphyrins showcases their potential to revolutionize current methodologies in both industry and medicine.