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Cyanomethyl 2-(benzyloxycarbonylamino)acetate

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Identification
Molecular formula
C12H12N2O4
CAS number
28772-81-8
IUPAC name
cyanomethyl 2-(benzyloxycarbonylamino)acetate
State
State

The compound is a solid at room temperature. Its crystalline nature contributes to a stable and somewhat brittle state that is easily powdered for use in various applications.

Melting point (Celsius)
95.00
Melting point (Kelvin)
368.15
Boiling point (Celsius)
250.00
Boiling point (Kelvin)
523.15
General information
Molecular weight
246.24g/mol
Molar mass
246.2570g/mol
Density
1.2000g/cm3
Appearence

Cyanomethyl 2-(benzyloxycarbonylamino)acetate typically appears as a white to off-white crystalline solid. The compound is often supplied in a powdered form and has a tendency to clump together due to static charge.

Comment on solubility

Solubility of Cyanomethyl 2-(benzyloxycarbonylamino)acetate

Cyanomethyl 2-(benzyloxycarbonylamino)acetate, featuring the chemical formula represented as RCH2CNCOOR', shows intriguing solubility characteristics that are vital for its applications in various fields, including medicinal chemistry.

Factors Influencing Solubility

Several factors can determine the solubility of this compound:

  • Polar vs. Nonpolar: The presence of polar functional groups, such as -CN and -COO, generally enhances solubility in polar solvents like water.
  • Solvent Interaction: Its solubility can markedly change based on the solvent types; for instance, it may dissolve well in organic solvents due to its nonpolar characteristics while exhibiting limited solubility in highly polar solvents.
  • Hydrogen Bonding: The capability of the compound to engage in hydrogen bonding can significantly impact its solubility. For example, the amino group may interact well with water, enhancing solubility.

Expected Solubility

In conclusion, one might predict that:

  • It will show moderate solubility in polar solvents.
  • You may observe higher solubility in organic solvents due to hydrophobic interactions.
  • Solubility can be further affected by temperature and pH levels, indicating the importance of environmental conditions.

Thus, understanding the solubility of cyanomethyl 2-(benzyloxycarbonylamino)acetate is critical for enhancing its utility in various applications where precise solubility behavior is essential.

Interesting facts

Interesting Facts about Cyanomethyl 2-(Benzyloxycarbonylamino)acetate

Cyanomethyl 2-(benzyloxycarbonylamino)acetate is a fascinating compound with diverse applications in the field of organic chemistry. It integrates various functional groups that enhance its reactivity and usefulness. Here are some notable aspects:

  • Functional Diversity: The compound features both a cyanomethyl group and an amino acid derivative, making it a versatile intermediate for synthesizing other complex molecules.
  • Importance in Synthesis: It plays a crucial role in peptide synthesis, which is essential for the development of pharmaceuticals and biologically active compounds.
  • Research Applications: Scientists are exploring its potential as a building block in the synthesis of new drugs, particularly in oncology and antibiotic research.
  • Carbonyl Group Reactivity: The benzyloxycarbonylamino (-N(H)-C(=O)-O-Ph) moiety functions as a protecting group in reactions, retaining the integrity of the amino functional group during chemical transformations.
  • Green Chemistry Perspective: As a compound derived from amino acids, it aligns with the principles of green chemistry, promoting sustainable practices in organic synthesis.

The integration of these properties not only makes cyanomethyl 2-(benzyloxycarbonylamino)acetate a compound of interest but also drives innovation in designing new synthetic routes and applications. As research continues to shed light on its potential, this compound stands at the intersection of practical applications and theoretical exploration in the realm of chemistry.

Synonyms
2899-56-1
GLYCINE, N-CARBOXY-, N-BENZYL ESTER, CYANOMETHYL ESTER
N-Carbobenzoxyglycine cyanomethyl ester
BRN 1996760
4-06-00-02288 (Beilstein Handbook Reference)
CHEMBL3247326
DTXSID40183184