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Cyanomethyl N-Cbz-L-phenylalaninate

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Identification
Molecular formula
C18H18N2O3
CAS number
.
IUPAC name
cyanomethyl (2S)-2-(benzyloxycarbonylamino)-3-phenyl-propanoate
State
State

At room temperature, Cyanomethyl N-Cbz-L-phenylalaninate is in a solid state, appearing as a crystalline powder. It is typically stored in a cool, dry place and is stable under normal conditions.

Melting point (Celsius)
89.50
Melting point (Kelvin)
362.65
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
284.31g/mol
Molar mass
284.3110g/mol
Density
1.2300g/cm3
Appearence

Cyanomethyl N-Cbz-L-phenylalaninate typically appears as a white to off-white crystalline solid. The compound is used often in research and organic synthesis, appearing under standard lighting as non-descript powdery material.

Comment on solubility

Solubility of Cyanomethyl (2S)-2-(benzyloxycarbonylamino)-3-phenyl-propanoate

The solubility of cyanomethyl (2S)-2-(benzyloxycarbonylamino)-3-phenyl-propanoate in various solvents can provide insightful information for its application. Typically, the solubility characteristics of such organic compounds are influenced by several factors:

  • Polarity: The presence of functional groups such as benzyloxycarbonyl and cyano impacts the compound's polarity, affecting how it interacts with different solvents.
  • Solvent Interaction: This compound may exhibit higher solubility in polar solvents like dimethyl sulfoxide (DMSO) or methanol due to its polar character.
  • Temperature Influence: Solubility can increase with temperature. Therefore, heating may enhance dissolution rates in suitable solvents.
  • Concentration Preferences: The solubility might vary significantly with concentration; thus, it is crucial to assess its behavior in both dilute and concentrated solutions.

In practice, solubility studies often reveal that compounds with aromatic rings, such as the phenyl group in this case, can sometimes lead to lower solubility in water due to hydrophobic interactions. However, the overall solubility profile of cyanomethyl (2S)-2-(benzyloxycarbonylamino)-3-phenyl-propanoate should be empirically determined, keeping in mind the interplay of the above factors. Conducting comprehensive solubility tests can not only provide practical handling insights but also guide its use in various applications.

Interesting facts

Interesting Facts About Cyanomethyl (2S)-2-(benzyloxycarbonylamino)-3-phenyl-propanoate

The compound cyanomethyl (2S)-2-(benzyloxycarbonylamino)-3-phenyl-propanoate is a fascinating molecule that stands out in the field of organic chemistry for several reasons:

  • Pharmaceutical Potential: This compound is noteworthy for its potential applications in pharmaceuticals. Its structural features suggest it could be useful in drug design, particularly for targeting specific enzymes or proteins in the body.
  • Chirality: The (2S) configuration indicates the presence of chirality, which is a crucial aspect in medicinal chemistry. Chirality affects how molecules interact with biological systems, often resulting in different biological activities for enantiomers.
  • Functional Groups: Featuring a cyanomethyl group and a benzyloxycarbonyl moiety, this compound demonstrates interesting reactivity patterns, making it a valuable intermediate in organic synthesis. The presence of multiple functional groups allows for diverse chemical transformations.
  • Synthetic Routes: Chemists often study compounds like this one to explore new methods of synthesis. Its unique structure can inspire novel approaches to create complex organic molecules with valuable properties.
  • Experimental Studies: As a subject of ongoing research, cyanomethyl (2S)-2-(benzyloxycarbonylamino)-3-phenyl-propanoate is often investigated for its reactivity in various chemical reactions, contributing to the understanding of organic reaction mechanisms.

In summary, this compound exemplifies how intricate organic molecules can offer significant insights into both chemistry and potential therapeutic avenues. Its complex structure invites further exploration and showcases the innovative spirit of chemical research.

Synonyms
BRN 4331278
7663-85-6
ALANINE, N-BENZYLOXYCARBONYL-3-PHENYL-, CYANOMETHYL ESTER, L-
L-N-Benzyloxycarbonyl-3-phenylalanine cyanomethyl ester
DTXSID40227456
DTXCID40149947
Z-L-Phe-OCH2CN
CHEMBL3247276
QDAFQGLLNQPQAT-KRWDZBQOSA-N