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Cyclohexane-1,4-diol

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Identification
Molecular formula
C6H12O2
CAS number
556-48-9
IUPAC name
cyclohexane-1,4-diol
State
State

At room temperature, cyclohexane-1,4-diol is in a solid state. It is stable under normal conditions but needs to be stored in a cool, dry place due to its hygroscopic nature.

Melting point (Celsius)
101.00
Melting point (Kelvin)
374.15
Boiling point (Celsius)
305.00
Boiling point (Kelvin)
578.15
General information
Molecular weight
116.16g/mol
Molar mass
116.1590g/mol
Density
1.0532g/cm3
Appearence

Cyclohexane-1,4-diol typically appears as a colorless solid. It may exhibit crystalline characteristics depending on purity and form. The solid is hygroscopic, which means it can absorb moisture from the environment.

Comment on solubility

Solubility of Cyclohexane-1,4-diol

Cyclohexane-1,4-diol, characterized by the formula C6H10O2, exhibits interesting solubility properties due to its unique structure. This compound, containing two hydroxyl (–OH) groups, enhances its ability to engage in hydrogen bonding, which significantly influences its solubility in various solvents.

Key Solubility Characteristics:

  • Soluble in Water: Cyclohexane-1,4-diol is moderately soluble in water, thanks to its polar hydroxyl groups that interact favorably with water molecules.
  • Solubility in Organic Solvents: This compound shows a good degree of solubility in organic solvents, especially those that can engage in hydrogen bonding, such as alcohols and ethers.
  • Temperature Dependency: The solubility of cyclohexane-1,4-diol may vary with temperature; generally, higher temperatures can increase solubility in most solvents.
  • Hydrogen Bonding: The presence of the two hydroxyl groups allows for intramolecular and intermolecular hydrogen bonding, which is crucial for determining its solubility behavior.

In summary, cyclohexane-1,4-diol showcases a balanced solubility profile that makes it versatile for use in both aqueous and organic environments. Its behavior under various conditions, particularly in the presence of more polar solvents, underscores the importance of its -OH functional groups in contributing to its solubility characteristics.

Interesting facts

Interesting Facts about Cyclohexane-1,4-diol

Cyclohexane-1,4-diol is a fascinating compound that presents a variety of interesting features from both chemical and practical perspectives. Here are some key points to consider:

  • Structure and Stability: The cyclic structure of cyclohexane lends itself to a unique stability due to its ability to minimize torsional strain. The hydroxyl groups present at the 1 and 4 positions allow for intramolecular hydrogen bonding, further enhancing stability.
  • Applications: This compound plays a crucial role in organic synthesis and is often used as a precursor in the manufacture of certain types of plastics, resins, and cosmetic products, showcasing its versatility in industrial applications.
  • Hydrophilicity: The presence of the two hydroxyl functional groups increases the overall polarity of the molecule, making it more hydrophilic than its non-hydroxylated counterparts. This property can influence solubility and interactions with other compounds.
  • Biological Relevance: Cyclohexane-1,4-diol has been studied for its potential biological activities. Although it is not commonly found in nature, its structural characteristics could offer insights into developing new pharmaceuticals.
  • Research Insights: Scientists are intrigued by this compound for its potential applications in green chemistry initiatives, as well as its role in biocompatible materials. Continued research may reveal new functionalities and uses.

In summary, cyclohexane-1,4-diol is not only significant in terms of its chemical properties and stability but also offers a glimpse into the potential for innovative applications and further research in the fields of chemistry and materials science.

Synonyms
1,4-CYCLOHEXANEDIOL
Cyclohexane-1,4-diol
Quinitol
Hexahydrohydroquinone
Quinitol,c&t
EINECS 209-126-2
1,4-Cyclohexanediol,c&t
1,4-Cyclohexanediol cis+trans
AI3-52305
DTXSID20871178
NSC 5651
Cyclohexane1,4diol
DTXCID00818849
209-126-2
vkonpudbrvkqlm-uhfffaoysa-n
cis-1,4-Cyclohexanediol
trans-1,4-Cyclohexanediol
556-48-9
6995-79-5
931-71-5
trans-Cyclohexane-1,4-diol
CIS-CYCLOHEXANE-1,4-DIOL
1,4-Cyclohexanediol, trans-
1,4-Cyclohexanediol, cis-
trans-1,4-Dihydroxycyclohexane
MFCD00001448
(1r,4r)-cyclohexane-1,4-diol
MFCD00063612
MFCD00075462
cis-1,4-Dihydroxycyclohexane
(1s,4s)-cyclohexane-1,4-diol
1,4-Cyclohexanediol (Cis/Trans Mixture)
1,4-cyclohexandiol
1,4-Dihydroxycyclohexane; NSC 5651; Quinitol
1,4-Cyclohexanediol, cis + trans
NSC 5730
EINECS 213-240-8
1,a4-aCyclohexanediol
AI3-06464
1,4-Dihydroxycyclohexane
cis-4-hydroxy-cyclohexanol
SCHEMBL28182
1,4-Cyclohexanediol, 99%
SCHEMBL102859
SCHEMBL275681
SCHEMBL787503
1,4-Cyclohexanediol, (E)-
1,4-Cyclohexanediol, (Z)-
(trans)-cyclohexane-1,4-diol
CHEMBL3948618
DTXSID60878843
DTXSID60883614
NSC5651
NSC5730
NSC-5651
NSC-5730
STR08594
rac-(1s,4s)-cyclohexane-1,4-diol
TD8009
AKOS006282972
AKOS006283462
AKOS015912876
AB02551
CS-W005575
CS-W007850
PB27420
AS-50386
SY001809
SY040970
SY099933
DB-003159
DB-008704
DB-318939
C2319
C2320
CS-0049754
NS00042681
NS00080163
EN300-75448
P10063
Q16912255
Z1178486717
71J