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Carbidopa

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Identification
Molecular formula
C10H14ClNO4
CAS number
38821-49-7
IUPAC name
cyclohexyl-[2-(3,4-dihydroxyphenyl)-2-oxo-ethyl]ammonium;chloride
State
State

At room temperature, Carbidopa is a solid. It is usually presented in the form of tablets for medicinal use.

Melting point (Celsius)
204.00
Melting point (Kelvin)
477.15
Boiling point (Celsius)
181.20
Boiling point (Kelvin)
454.35
General information
Molecular weight
226.24g/mol
Molar mass
226.2360g/mol
Density
2.0308g/cm3
Appearence

Carbidopa appears as a white to off-white crystalline powder. It is hygroscopic and generally stored in a tightly closed container to prevent moisture absorption.

Comment on solubility

Solubility of cyclohexyl-[2-(3,4-dihydroxyphenyl)-2-oxo-ethyl]ammonium chloride

The solubility of cyclohexyl-[2-(3,4-dihydroxyphenyl)-2-oxo-ethyl]ammonium chloride in various solvents is an interesting aspect to examine, particularly due to its unique structure. This compound features a cyclic alkane and multiple functional groups, which significantly influence its solubility profile.

  • Water Solubility: The presence of the ammonium group often indicates that the compound may exhibit good solubility in water due to ionic interactions. However, the bulkiness of the cyclohexyl group may hinder this to some extent.
  • Organic Solvents: It is likely to show better solubility in polar organic solvents like alcohols or dimethyl sulfoxide (DMSO), as these solvents can stabilize the ammonium ion and enhance solubilization.
  • Solvation Effects: The type of solvent used can also lead to varying degrees of solvo-complex formation, which can affect the overall solubility.

As a general guideline, it can be said that the compound might be:

  1. Readily soluble in polar protic solvents
  2. Moderately soluble in polar aprotic solvents
  3. Poorly soluble in non-polar solvents

In conclusion, while the precise solubility can vary based on experimental conditions and concentration, understanding the influence of molecular structure is key. As noted, "The solubility of a compound is fundamentally a reflection of its molecular interactions." Thus, one should consider both ionic and hydrophobic characteristics when evaluating solubility parameters for cyclohexyl-[2-(3,4-dihydroxyphenyl)-2-oxo-ethyl]ammonium chloride.

Interesting facts

Interesting Facts About Cyclohexyl-[2-(3,4-dihydroxyphenyl)-2-oxo-ethyl]ammonium Chloride

Cyclohexyl-[2-(3,4-dihydroxyphenyl)-2-oxo-ethyl]ammonium chloride is a compound that showcases the fascinating intersection of organic chemistry and pharmacology. This compound is particularly notable for its potential biological activity, particularly with its dual function as both a basic ammonium derivative and a moiety that connects with phenolic compounds. Here are some engaging insights:

  • Biochemical Importance: The presence of the 3,4-dihydroxyphenyl group indicates potential antioxidant activity, which is a hot topic in medicinal chemistry. Compounds with similar structures often show promise in combating oxidative stress.
  • Developing Applications: Research is ongoing into the use of this compound in the development of pharmaceuticals. It may influence a variety of biological mechanisms, including enzyme inhibition and receptor modulation.
  • Structural Diversity: The cyclohexyl group contributes to the *lipophilicity* of the molecule, which can influence its ability to cross biological membranes and interact with cellular targets.
  • Environmental Impact: Compounds like this one are also being examined for their *environmental effects*, particularly in how they might impact living organisms upon release into ecosystems.
  • Intriguing Synthesis: The synthesis of this compound can involve various methods, often utilizing the principles of organic synthesis such as nucleophilic substitutions and heterocycle formations, making it a compelling subject for chemists.

In summary, cyclohexyl-[2-(3,4-dihydroxyphenyl)-2-oxo-ethyl]ammonium chloride is more than just a chemical compound; it represents a fusion of organic chemistry and biological relevance. As research continues to unfold, we may uncover even more exciting applications and mechanisms of action that this compound embodies.

Synonyms
2-(Cyclohexylamino)-3',4'-dihydroxyacetophenone hydrochloride
16149-19-2
N-Cyclohexyl noradrenalone hydrochloride
N-Cyclohexylnoradrenalone hydrochloride
ACETOPHENONE, 2-(CYCLOHEXYLAMINO)-3',4'-DIHYDROXY-, HYDROCHLORIDE