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Cyclohexyl 3-(aziridin-1-yl)propanoate

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Identification
Molecular formula
C12H21NO2
CAS number
170757-99-6
IUPAC name
cyclohexyl 3-(aziridin-1-yl)propanoate
State
State

At room temperature, cyclohexyl 3-(aziridin-1-yl)propanoate is typically in a liquid state. It is often stored in a well-closed container to prevent evaporation and contamination.

Melting point (Celsius)
-52.00
Melting point (Kelvin)
221.15
Boiling point (Celsius)
121.50
Boiling point (Kelvin)
394.65
General information
Molecular weight
211.29g/mol
Molar mass
211.2880g/mol
Density
1.0540g/cm3
Appearence

Cyclohexyl 3-(aziridin-1-yl)propanoate is typically a colorless to pale yellow liquid. Its appearance can vary slightly based on purity and other factors.

Comment on solubility

Solubility of Cyclohexyl 3-(aziridin-1-yl)propanoate

Cyclohexyl 3-(aziridin-1-yl)propanoate presents intriguing solubility characteristics. This compound's solubility can largely depend on the nature of the solvent and the molecular interactions involved. Here are some key points to consider:

  • Polarity: The presence of the aziridine group contributes to the overall polarity of the molecule, which may enhance its solubility in polar solvents such as water and alcohols.
  • Hydrophobic Character: The cyclohexyl group adds a hydrophobic character, suggesting that this compound may also show reasonable solubility in non-polar solvents like hexane or toluene.
  • Temperature Dependence: Solubility might be influenced by temperature; typically, higher temperatures increase the solubility of organic compounds.

As with many organic compounds, it is essential to consider the solubility in different solvents for practical applications. Research indicates that solubility can vary significantly based on environmental variables, thus it’s crucial to conduct specific experiments for precise solubility data.

In summary, the solubility behavior of cyclohexyl 3-(aziridin-1-yl)propanoate is likely a complex interplay of its molecular structure and the solvents used, making it an interesting subject for further study.

Interesting facts

Interesting Facts about Cyclohexyl 3-(aziridin-1-yl)propanoate

Cyclohexyl 3-(aziridin-1-yl)propanoate is a fascinating compound that merits attention in various fields of chemistry, particularly in organic synthesis and medicinal chemistry. Here are some intriguing aspects to consider:

  • Structural Versatility: The compound features a cyclohexyl group, which is a well-known moiety in organic chemistry, imparting stability and unique interaction potentials due to its six-membered ring structure.
  • Aziridine Ring: The inclusion of an aziridine ring is particularly noteworthy. This three-membered, nitrogen-containing ring is known for its high reactivity and potential usefulness as an intermediate in drug synthesis.
  • Synthetic Applications: Due to its unique structure, cyclohexyl 3-(aziridin-1-yl)propanoate can serve as a valuable building block in the creation of more complex molecules, particularly in the pharmaceutical industry.
  • Biological Relevance: Compounds containing aziridine rings have shown potential in medicinal chemistry, with activities related to antitumor and antimicrobial properties. This opens avenues for exploring the bioactivity of cyclohexyl 3-(aziridin-1-yl)propanoate in drug design.
  • An Example of Modulation: By varying the substituents on the aziridine or the cyclohexyl group, researchers can potentially modulate the compound's properties, such as its lipophilicity or reactivity towards biological targets, leading to enhanced therapeutic profiles.

In summary, cyclohexyl 3-(aziridin-1-yl)propanoate stands out for its unique structural characteristics and significant potential in synthetic and medicinal chemistry. As research progresses, further investigations could unveil even more uses and insights regarding this compound, making it an exciting topic for aspiring chemists and seasoned researchers alike.

Synonyms
1-AZIRIDINEPROPIONIC ACID, CYCLOHEXYL ESTER
1-Aziridinepropanoic acid, cyclohexyl ester
NSC 101293
24116-19-6
DTXSID40178838
RefChem:227746
DTXCID00101329
NCIOpen2_001909
NSC101293
NSC-101293