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Cyclohexyl(4-fluorophenyl)(3-piperidinopropyl)silanol

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Identification
Molecular formula
C22H36FNO1Si
CAS number
141776-32-1
IUPAC name
cyclohexyl-(4-fluorophenyl)-hydroxy-[3-(1-piperidyl)propyl]silane
State
State

At room temperature, cyclohexyl(4-fluorophenyl)(3-piperidinopropyl)silanol is in a liquid state.

Melting point (Celsius)
12.50
Melting point (Kelvin)
285.65
Boiling point (Celsius)
210.00
Boiling point (Kelvin)
483.15
General information
Molecular weight
325.54g/mol
Molar mass
325.5380g/mol
Density
1.1500g/cm3
Appearence

Cyclohexyl(4-fluorophenyl)(3-piperidinopropyl)silanol typically presents as a colorless to pale yellow liquid. The compound may exhibit a distinctive odor characteristic of organosilicon compounds, and being an organosilicon derivative, it generally maintains a glassy liquid form at room temperature.

Comment on solubility

Solubility of Cyclohexyl-(4-fluorophenyl)-hydroxy-[3-(1-piperidyl)propyl]silane

The solubility of C22H36FNO1Si, or cyclohexyl-(4-fluorophenyl)-hydroxy-[3-(1-piperidyl)propyl]silane, can be quite complex due to its unique molecular structure. Understanding its solubility characteristics is essential for various applications in chemical processes and formulations.

Key Solubility Factors:

  • Hydrophobic Characteristics: The presence of cyclohexyl and fluorophenyl groups may lead to hydrophobic interactions, which often result in lower solubility in polar solvents.
  • Polar Functional Groups: The hydroxy group can enhance solubility in polar solvents such as alcohols and water, potentially due to hydrogen bonding.
  • Chain Length: The length and branching of the propyl piperidine chain can influence solubility, as longer chains typically reinforce hydrophobic properties.
  • Temperature Influence: Solubility can vary significantly with temperature, often increasing in non-polar solvents as temperature rises.

Furthermore, it's important to consider the solvent environment in which this compound is placed. For example, it may exhibit better solubility in:

  • Organic solvents (e.g., dichloromethane, ethyl acetate)
  • Some mixed-solvent systems with both polar and non-polar characteristics

In practical applications, conducting solubility tests in relevant solvents remains crucial for optimizing the usage of cyclohexyl-(4-fluorophenyl)-hydroxy-[3-(1-piperidyl)propyl]silane in various chemical formulations.

Interesting facts

Interesting Facts about Cyclohexyl-(4-fluorophenyl)-hydroxy-[3-(1-piperidyl)propyl]silane

Cyclohexyl-(4-fluorophenyl)-hydroxy-[3-(1-piperidyl)propyl]silane is an intriguing compound with vast potential in various fields, primarily in organic chemistry and pharmacology. Here are some captivating details:

  • Silane Chemistry: This compound features a silane group, which is known for its reactivity and ability to form strong bonds with various substrates. Such characteristics make silanes useful in material science, particularly in coatings and surface modification.

  • Fluorinated Compounds: The presence of a fluorine atom significantly modifies the chemical properties. Fluorinated compounds often exhibit improved bioavailability and stability, which are critical in the development of pharmaceutical agents.

  • Piperidine Structure: The inclusion of a piperidine ring enhances the compound's ability to interact with biological systems. Piperidine derivatives are common in medicinal chemistry due to their pharmacological properties. They can act as analgesics, anti-anxiety agents, and more.

  • Hydroxy Group: The hydroxy (-OH) functional group plays a crucial role in the compound's polarity and reactivity. This group can participate in various chemical reactions, potentially lending to biological activity.

As researchers delve deeper into its properties, the compound could unveil unique applications swayed by its structure, bridging the gap between synthetic chemistry and practical utilizations in drug discovery and material science. As Andrew E. W. Smith once stated, "Understanding the nuances of chemical interactions paves the pathway for innovation."

Synonyms
pFHHSiD
p-F-Hhsid
116679-83-5
FHHSiD
4-fluorohexahydrosiladifenidol
p-Fluoro-hexahydro-sila-difenidol
p-Fluoro-hexahydro-sila-diphenidol
p-Fluorohexahydrosiladyphenidol
cyclohexyl-(4-fluorophenyl)-hydroxy-(3-piperidin-1-ylpropyl)silane
XEO1GM7K2V
p-Fluorohexahydrosiladifenidol
p-pluorohexahydrosiladyphenidol
Cyclohexyl-(4-fluorophenyl)-hydroxy-[3-(1-piperidyl)propyl]silane
Silanol, cyclohexyl(4-fluorophenyl)(3-(1-piperidinyl)propyl)-
p-Fluorohexahydro-sila-difenidol
Silanol, cyclohexyl(4-fluorophenyl)[3-(1-piperidinyl)propyl]-
1-CYCLOHEXYL-1-(4-FLUOROPHENYL)-1-(3-(1-PIPERIDINYL)PROPYL)SILANOL
Silanol, 1-cyclohexyl-1-(4-fluorophenyl)-1-[3-(1-piperidinyl)propyl]-
SILANOL, 1-CYCLOHEXYL-1-(4-FLUOROPHENYL)-1-(3-(1-PIPERIDINYL)PROPYL)-
Cyclohexyl(4-fluorophenyl)(3-(piperidin-1-yl)propyl)silanol
cyclohexyl(4-fluorophenyl)[3-(piperidin-1-yl)propyl]silanol
p-FHSD
UNII-XEO1GM7K2V
Lopac0_000608
GTPL308
CHEMBL1256682
BDBM85381
DTXSID60922113
ZNSZQJHTFRQUPD-UHFFFAOYSA-N
PDSP1_000968
PDSP2_000952
CCG-204697
SDCCGSBI-0050590.P002
NCGC00015490-02
NCGC00015490-03
NCGC00015490-05
NCGC00162201-01
CAS_116679-83-5
L001178
Q27078090