Skip to main content

Cyclamate

ADVERTISEMENT
Identification
Molecular formula
C6H11NO3S
CAS number
100-88-9, 103-12-8
IUPAC name
cyclohexylsulfamic acid;2-(1-phenylethoxy)guanidine
State
State

At room temperature, cyclamate is in a solid state. Its solid form allows it to be easily handled and incorporated into a variety of food and beverage products.

Melting point (Celsius)
170.00
Melting point (Kelvin)
443.15
Boiling point (Celsius)
290.00
Boiling point (Kelvin)
563.15
General information
Molecular weight
201.26g/mol
Molar mass
201.2570g/mol
Density
1.2600g/cm3
Appearence

Cyclamate appears as a white crystalline powder. It is odorless and possesses a sweet taste. Cyclamate is widely used as a non-nutritive sweetener and is often found in combination with other sweeteners to enhance flavor profiles. It is highly soluble in water, making it suitable for use in a variety of liquid and food products.

Comment on solubility

Solubility of Cyclohexylsulfamic Acid

Cyclohexylsulfamic acid, with its unique structure, exhibits interesting solubility characteristics. This compound tends to be partially soluble in water, which can be attributed to the presence of the sulfonamide functional group that facilitates hydrogen bonding due to its polar nature.

Factors Influencing Solubility

The solubility of cyclohexylsulfamic acid can vary based on several factors, such as:

  • Temperature: As the temperature increases, the solubility of many compounds, including cyclohexylsulfamic acid, typically increases.
  • pH Level: Being an acid, its solubility may be affected by the pH of the solution, with greater soluble forms existing at more alkaline conditions.
  • Presence of Other Solvents: The solubility may also enhance significantly in organic solvents or mixtures that can interact favorably with the cyclohexyl moiety.

2-(1-Phenylethoxy)guanidine Solubility

The second compound, 2-(1-phenylethoxy)guanidine, presents its own solubility profile. This compound is generally more soluble in organic solvents and shows limited solubility in water. Its aromatic and etheric components contribute to its preference for non-polar environments.

Comparative Remarks

When comparing these two compounds, it is evident that:

  • Cyclohexylsulfamic acid may be more versatile in aqueous solutions.
  • 2-(1-phenylethoxy)guanidine is likely more favored in organic synthesis contexts.

Understanding these solubility properties is crucial for applications involving these compounds, especially in formulations, reactions, or when considering their environmental impact.

Interesting facts

Interesting Facts about Cyclohexylsulfamic Acid and 2-(1-phenylethoxy)guanidine

Cyclohexylsulfamic acid and 2-(1-phenylethoxy)guanidine are intriguing compounds that showcase the versatility of nitrogen-containing organic molecules. Here are some fascinating insights into their properties and applications:

  • Cyclohexylsulfamic Acid is part of a larger family known as sulfamates. These compounds possess a sulfonamide functional group, which gives them unique characteristics and potential for various applications.
  • Biological Activity: Many sulfamic acids, including cyclohexylsulfamic acid, have been studied for their potential therapeutic effects. Research suggests they may have applications in fields such as anti-inflammatory and antimicrobial medications.
  • Ubiquitous Use: This compound serves as an important reagent in organic synthesis and can facilitate the production of more complex molecules. Its properties allow it to act as an efficient catalyst in various chemical reactions.
  • 2-(1-phenylethoxy)guanidine is another remarkable compound with applications in medicinal chemistry. This guanidine derivative has been investigated for its role in the development of new drugs.
  • Structure-Activity Relationship: The modification of the phenyl group in 2-(1-phenylethoxy)guanidine can significantly affect its biological activity. Understanding these relationships is essential for drug design.

In summary, both cyclohexylsulfamic acid and 2-(1-phenylethoxy)guanidine serve as potent examples of how organic compounds can intersect with pharmacology and chemistry. Their unique structures and properties make them valuable in research and development, paving the way for potential innovations in drug synthesis and therapeutic solutions.

Synonyms
((alpha-Methylbenzyl)oxy)guanidine cyclohexanesulfamate
741-01-5
GUANIDINE, ((alpha-METHYLBENZYL)OXY)-, CYCLOHEXANESULFAMATE
DTXSID20995540
Cyclohexylsulfamic acid--N-(1-phenylethoxy)guanidine (1/1)