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Cyclohexylsulfamic acid

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Identification
Molecular formula
C6H13NO3S
CAS number
100-88-3
IUPAC name
cyclohexylsulfamic acid;3-[1-hydroxy-2-(methylamino)ethyl]phenol
State
State

At room temperature, cyclohexylsulfamic acid is typically a solid.

Melting point (Celsius)
205.00
Melting point (Kelvin)
478.15
Boiling point (Celsius)
273.00
Boiling point (Kelvin)
546.15
General information
Molecular weight
197.68g/mol
Molar mass
197.6780g/mol
Density
1.7696g/cm3
Appearence

Cyclohexylsulfamic acid powder typically appears as a white crystalline solid. It is often fine and uniform in texture, and it is odorless or has a slight medicinal smell.

Comment on solubility

Solubility of Cyclohexylsulfamic Acid and 3-[1-Hydroxy-2-(methylamino)ethyl]phenol

Cyclohexylsulfamic acid and 3-[1-hydroxy-2-(methylamino)ethyl]phenol exhibit distinct solubility characteristics influenced by their molecular structures. Understanding their solubility is crucial for their applications in various chemical processes.

Cyclohexylsulfamic Acid

This compound tends to exhibit good solubility in polar solvents, particularly water and alcohols, due to its sulfonamide functional group that can form hydrogen bonds. Key points include:

  • Water Solubility: Moderately soluble in water, enhancing its utility in aqueous formulations.
  • Solvent Compatibility: Soluble in ethanol and methanol, making it versatile for various chemical reactions.
  • Effect of Temperature: Solubility may increase with temperature, a common behavior among many organic acids.

As a result, cyclohexylsulfamic acid is favored in applications requiring aqueous solubility and reactivity.

3-[1-Hydroxy-2-(methylamino)ethyl]phenol

This compound shows variable solubility behaviors due to its phenolic structure and additional functional groups:

  • Water Solubility: Generally, phenols have lower solubility in water; however, the presence of the hydroxyl and amino groups increases its solubility.
  • Organic Solvents: It is more soluble in organic solvents like ethanol and dimethyl sulfoxide (DMSO).
  • pH Influence: The solubility can significantly change with pH, especially in the presence of proton donors or acceptors affecting the ionization state.

Overall, 3-[1-hydroxy-2-(methylamino)ethyl]phenol’s solubility properties are enhanced by intramolecular interactions and environmental conditions.

In conclusion, understanding the solubility of these compounds not only aids in their practical use but also enhances our grasp of their reactivity and role in chemical formulations.

Interesting facts

Interesting Facts about Cyclohexylsulfamic Acid and 3-[1-hydroxy-2-(methylamino)ethyl]phenol

Cyclohexylsulfamic acid is an intriguing compound not only for its industrial applications but also for its role in various chemical reactions. As a sulfonic acid derivative, it exhibits excellent water solubility, making it a versatile candidate for various synthetic applications.

Applications and Uses

  • Intermediate in Synthesis: It serves as an intermediate in the synthesis of various pharmaceuticals and agrochemicals.
  • Absorption Agent: Its unique structure allows it to act as an effective absorption agent in certain chemical reactions.
  • Potential in Research: Scientists are exploring its reactivity to develop new methodologies in organic synthesis.

3-[1-hydroxy-2-(methylamino)ethyl]phenol, on the other hand, is noted for its biological significance.

Biological Relevance

  • Possible Medicinal Properties: This compound has garnered attention for its potential medicinal properties, particularly as a candidate in drug development against neurological disorders.
  • Metabolism Studies: Research is ongoing to understand how this compound interacts with biological systems, especially in terms of metabolism and clearance.
  • Involvement in Biochemical Pathways: It may play a role in specific biochemical pathways, raising interest in its functionality as a biochemical tool.

For chemists and researchers alike, understanding the properties and potential applications of both Cyclohexylsulfamic acid and 3-[1-hydroxy-2-(methylamino)ethyl]phenol opens doors to innovative solutions in chemical synthesis and pharmaceuticals. Their unique functionalities make them subjects of ongoing study and exploration in the field of chemistry.