Skip to main content

Bambuterol hydrochloride

ADVERTISEMENT
Identification
Molecular formula
C18H29ClFN2O5
CAS number
81732-46-9
IUPAC name
dibutyl-[3-(2-ethoxy-5-fluoro-benzoyl)oxypropyl]ammonium;chloride
State
State

At room temperature, Bambuterol hydrochloride is in a solid state, typically used as a powder for pharmaceutical formulations.

Melting point (Celsius)
106.00
Melting point (Kelvin)
379.15
Boiling point (Celsius)
237.00
Boiling point (Kelvin)
510.15
General information
Molecular weight
521.07g/mol
Molar mass
521.0740g/mol
Density
1.1300g/cm3
Appearence

Bambuterol hydrochloride appears as a white or off-white crystalline powder.

Comment on solubility

Solubility of Dibutyl-[3-(2-ethoxy-5-fluoro-benzoyl)oxypropyl]ammonium Chloride

The solubility of dibutyl-[3-(2-ethoxy-5-fluoro-benzoyl)oxypropyl]ammonium chloride is influenced by several factors related to its chemical structure, which includes both hydrophilic and hydrophobic components. Understanding the solubility profile of this compound can be crucial for its application in various fields.

Factors Affecting Solubility:

  • Ionization: As an ammonium salt, the compound tends to ionize in aqueous solutions, which generally enhances its solubility in water.
  • Hydrophobic Groups: The dibutyl group adds hydrophobic characteristics that may limit solubility in polar solvents.
  • Hydrophilic Substituents: The ethoxy and benzoyl groups can increase solubility in organic solvents due to their polar character.

In practical terms, it is essential to consider the following observations:

  • This compound is likely to be more soluble in organic solvents such as ethanol or acetone, given its hydrophobic parts.
  • In contrast, its solubility in water may be moderate, primarily due to the ionic nature of the ammonium chloride.

Overall, while dibutyl-[3-(2-ethoxy-5-fluoro-benzoyl)oxypropyl]ammonium chloride may exhibit moderate to good solubility in select solvents, its behavior in different environments will vary significantly based on the solvent's polarity and the compound's unique structural features.

Interesting facts

Interesting Facts about Dibutyl-[3-(2-Ethoxy-5-Fluoro-Benzoyl)Oxypropyl]Ammonium Chloride

Dibutyl-[3-(2-ethoxy-5-fluoro-benzoyl)oxypropyl]ammonium chloride is an intriguing compound that has garnered attention in the fields of chemistry and pharmacology for its unique properties and potential applications.

1. Structure and Composition

This compound is classified as a quaternary ammonium compound, characterized by its nitrogen atom fully bound to four alkyl groups. Notably, the inclusion of a fluorobenzoyl moiety enhances its biological relevance.

2. Biological Applications

  • Antimicrobial Activities: Compounds like dibutyl-[3-(2-ethoxy-5-fluoro-benzoyl)oxypropyl]ammonium chloride are often explored for their potential as antimicrobial agents, making them valuable in medical and industrial settings.
  • Drug Delivery: The unique amphiphilic nature allows the compound to interact favorably with cellular membranes, thereby facilitating drug delivery systems.

3. Synthesis and Reactions

The synthesis of this compound involves several steps, typically including alkylation reactions and coupling with appropriate benzoyl derivatives. The precision in synthesis is crucial for ensuring the desired properties of the final product.

4. Importance in Research

Given its complex structure, dibutyl-[3-(2-ethoxy-5-fluoro-benzoyl)oxypropyl]ammonium chloride serves as an interesting subject for research:

  • Research on its mechanism of action can reveal insights into how quaternary ammonium compounds interact with biological systems.
  • It provides a platform for developing new derivatives with enhanced efficacy or reduced toxicity.

5. Future Directions

The ongoing exploration of this compound may lead to novel therapeutic agents:

  • Customization: By modifying the side chains, researchers can tailor the compound for specific applications.
  • Broader Impact: Understanding its biochemical interactions may contribute to advancements in targeted drug therapies.

In conclusion, dibutyl-[3-(2-ethoxy-5-fluoro-benzoyl)oxypropyl]ammonium chloride highlights the intricate relationship between molecular structure and biological activity, making it a valuable compound for future exploration in chemistry and medicine.

Synonyms
2-Ethoxy-5-fluorobenzoic acid 3-(dibutylamino)propyl ester hydrochloride
3829-91-2
Fluoro-5-ethoxy-2-benzoate de gamma-dibutylaminopropyle chlorhydrate [French]
BENZOIC ACID, 2-ETHOXY-5-FLUORO-, 3-(DIBUTYLAMINO)PROPYL ESTER, HYDROCHLORIDE
Fluoro-5-ethoxy-2-benzoate de gamma-dibutylaminopropyle chlorhydrate