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Methanesulfonyl chloride

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Identification
Molecular formula
ClCH3SO2
CAS number
124-63-0
IUPAC name
dichloro-bis(methylsulfonyl)methane
State
State

At room temperature, methanesulfonyl chloride is a liquid. It is typically stored under inert gas to prevent reaction with atmospheric moisture, which could lead to its hydrolysis.

Melting point (Celsius)
-32.00
Melting point (Kelvin)
241.15
Boiling point (Celsius)
161.00
Boiling point (Kelvin)
434.15
General information
Molecular weight
127.14g/mol
Molar mass
127.1350g/mol
Density
1.3930g/cm3
Appearence

Methanesulfonyl chloride is a clear, colorless liquid. It may also be described as colorless to pale yellow, depending on purity and exposure to light. It emits a pungent odor and is recognized for its corrosive properties.

Comment on solubility

Solubility of Dichloro-bis(methylsulfonyl)methane

Dichloro-bis(methylsulfonyl)methane, known for its unique chemical properties, exhibits notable solubility characteristics. When considering the solubility of this compound, several factors come into play:

  • Polarity: The presence of sulfonyl groups contributes to its polarity, which can enhance solubility in polar solvents.
  • Solvent Compatibility: This compound demonstrates good solubility in common organic solvents such as dimethyl sulfoxide (DMSO) and acetone, while showing limited solubility in non-polar solvents.
  • Temperature Influence: As with many compounds, increasing temperature typically enhances solubility, particularly in organic media.

It's important to note that when investigating the solubility of dichloro-bis(methylsulfonyl)methane:

  • Experiments should be conducted to determine the exact solubility limits in various solvents.
  • Due to its unique structure, solubility tests can yield critical data for its applications in organic synthesis and pharmaceuticals.

In conclusion, understanding the solubility of dichloro-bis(methylsulfonyl)methane not only aids in predicting its behavior in different environments but also plays a crucial role in its practical applications.

Interesting facts

Interesting Facts about Dichloro-bis(methylsulfonyl)methane

Dichloro-bis(methylsulfonyl)methane is an intriguing compound that has garnered attention in both organic chemistry and industrial applications. Here are some compelling insights about this fascinating molecule:

  • Unique Structure: The molecule features two chlorine atoms and two methylsulfonyl groups attached to a central methane backbone. This unique configuration contributes to its reactivity and functionality in various chemical processes.
  • Role in Synthesis: This compound serves as a versatile intermediate in organic synthesis, particularly in the preparation of sulfonamide drugs. Its ability to introduce sulfonyl groups into various substrates makes it a valuable tool in medicinal chemistry.
  • Environmental Considerations: As with many chlorinated compounds, environmental impact is a significant consideration. Researchers are continually studying the degradation pathways of dichloro-bis(methylsulfonyl)methane to understand its behavior in ecosystems and to mitigate any potential risks associated with its use.
  • Functional Groups: The presence of sulfonyl groups enhances the compound's polarity, which can affect solubility and chemical interactions. This characteristic is particularly important in drug design, where solubility and bioavailability are crucial factors.

In the words of famed chemist Linus Pauling, “Chemistry is the science of change.” Dichloro-bis(methylsulfonyl)methane exemplifies this notion, demonstrating how a simple alteration in molecular structure can lead to significant changes in application and reactivity. As research continues, our understanding of such compounds expands, opening the door to innovations in both chemistry and pharmaceuticals.

Synonyms
22439-22-1
Dichlorobis(methylsulfonyl)methane
METHANE, DICHLOROBIS(METHYLSULFONYL)-
DTXSID20176978
Bismethylsulfonyldichloromethane
NSC 172286
BRN 1785334
NSC172286
RefChem:1089048
SCHEMBL5931320
DTXCID8099469
NSC-172286
DS-002564
METHANE,DICHLOROBIS(METHYLSULFONYL)-