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Nitracrine hydrochloride

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Identification
Molecular formula
C19H24N4O2Cl2
CAS number
51481-78-0
IUPAC name
diethyl-[2-[(1-nitroacridin-9-yl)ammonio]ethyl]ammonium;dichloride
State
State

Solid at room temperature.

Melting point (Celsius)
280.00
Melting point (Kelvin)
553.15
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.15
General information
Molecular weight
447.37g/mol
Molar mass
447.3660g/mol
Density
1.3400g/cm3
Appearence

Nitracrine hydrochloride typically appears as a yellow to orange crystalline solid.

Comment on solubility

Solubility of Diethyl-[2-[(1-nitroacridin-9-yl)ammonio]ethyl]ammonium; Dichloride

Diethyl-[2-[(1-nitroacridin-9-yl)ammonio]ethyl]ammonium; dichloride is a fascinating compound with unique solubility characteristics. Understanding these properties is vital for its applications in various fields, particularly in pharmaceuticals and chemical research.

General Solubility Insight

This compound is known to be soluble in polar solvents, such as water and alcohol. The solubility can be attributed to the presence of ionic ammonium groups, which interact favorably with polar solvents, facilitating dissolution.

Key Solubility Factors

  • Hydrophilicity: The ammonium moieties enhance its hydrophilic nature, allowing it to interact strongly with water molecules.
  • Ionic Nature: Being a salt (in this case, a dichloride), it exhibits high solubility in water, leveraging the dissociation of its ionic components.
  • Temperature Effects: Like many ionic compounds, its solubility generally increases with temperature, making it more soluble in warm conditions.

Practical Implications

The solubility of this compound can influence its biological activity, particularly in medicinal chemistry, where solubility is critical for bioavailability. Compounds with higher solubility can exhibit better absorption in biological systems. Awareness of its solubility can lead to the development of more effective formulations and dosing strategies.

As with any compound, it is essential to refer to experimental data to determine precise solubility values under specific conditions. Nonetheless, it is evident that diethyl-[2-[(1-nitroacridin-9-yl)ammonio]ethyl]ammonium; dichloride holds promise in various applications due to its favorable solubility characteristics.

Interesting facts

Interesting Facts About Diethyl-[2-[(1-nitroacridin-9-yl)ammonio]ethyl]ammonium Dichloride

This compound, often referred to in scientific discussions for its intriguing properties, plays a significant role in various fields, particularly in biochemistry and pharmacology.

Key Characteristics

  • Structure: The compound features a complex arrangement that includes a nitroacridine moiety, which is known for its fluorescent properties.
  • Biological Significance: Its biological activity stems from the acridine part of its structure, often associated with intercalation into DNA molecules – a crucial mechanism for many anticancer agents.
  • Pharmaceutical Potential: The presence of the ammonium groups suggests its potential use in drug design, particularly in developing compound libraries for targeting various diseases.

Applications in Research

Researchers find this compound particularly fascinating due to its multifaceted applications, such as:

  • Photodynamic Therapy: The compound's photophysical properties make it a candidate for use in targeted cancer therapies where light activation is applied to induce cytotoxic effects on cancer cells.
  • Fluorescent Probes: Owing to its fluorescent nature, it can be used in biological imaging, allowing scientists to visualize cellular processes in live cells.
  • Research Tool: It serves as a helpful tool in chemical biology to probe mechanisms of action of different chemical entities.

Quote from Research Community

As one researcher noted, "The unique properties of diethyl-[2-[(1-nitroacridin-9-yl)ammonio]ethyl]ammonium dichloride open new avenues for therapeutic exploration against difficult-to-treat conditions."

In summary, diethyl-[2-[(1-nitroacridin-9-yl)ammonio]ethyl]ammonium dichloride stands out not only for its complex structure but also for its potential impact in medicinal chemistry and beyond. Its continuous study could lead to breakthroughs in understanding drug interactions and therapeutic applications.

Synonyms
C-516
1-Nitro-9-(diethylaminoethylamine)-acridine dihydrochloride
17074-42-9
ACRIDINE, 9-((2-(DIETHYLAMINO)ETHYL)AMINO)-1-NITRO-, DIHYDROCHLORIDE
1-Nitro-9-(diethylaminoethylamino)-acridine-2 hydrochloride
C 516
1,2-Ethanediamine, N,N-diethyl-N'-(1-nitro-9-acridinyl)-, dihydrochloride
1,2-Ethanediamine, N,N-diethyl-N'-(1-nitro-9-acridinyl)-, dihydrochloride (9CI)