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Choline Salicylate

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Identification
Molecular formula
C13H19NO4
CAS number
2016-33-9
IUPAC name
diethyl-[2-[2-(1-naphthylmethyl)-3-tetrahydrofuran-2-yl-propanoyl]oxyethyl]ammonium;2-hydroxy-2-oxo-acetate
State
State

At room temperature, choline salicylate usually exists as a liquid. It is noteworthy that this state contributes to its application as a topical analgesic, providing ease of use and formulation into gels and solutions.

Melting point (Celsius)
-17.00
Melting point (Kelvin)
256.15
Boiling point (Celsius)
280.00
Boiling point (Kelvin)
553.15
General information
Molecular weight
219.24g/mol
Molar mass
219.2340g/mol
Density
1.2000g/cm3
Appearence

Choline salicylate is typically observed as a light brown or colorless liquid. It may also be found in a semi-solid state depending on the concentration and temperature. The compound is often used in pharmaceutical formulations, especially in oral gels for pain relief.

Comment on solubility

Solubility Characteristics

The compound diethyl-[2-[2-(1-naphthylmethyl)-3-tetrahydrofuran-2-yl-propanoyl]oxyethyl]ammonium;2-hydroxy-2-oxo-acetate exhibits fascinating solubility behavior.

Key Points on Solubility:

  • Solvent Dependency: Its solubility is highly dependent on the choice of solvent. Typically, it is expected to be more soluble in organic solvents like ethanol or methanol due to its hydrophobic characteristics.
  • Temperature Influence: An increase in temperature often enhances solubility; however, specific solubility data may vary based on experimental conditions.
  • pH Sensitivity: The solubility can also be influenced by the pH of the solution, particularly due to the ammonium functional groups that may become protonated or deprotonated.

As a general trend, compounds that contain structures like tetrahydrofuran and aromatic rings often showcase varied solubility profiles, owing to their unique intermolecular interactions. In summary, understanding the solubility of this compound necessitates considering these various factors, making it a subject of interest for chemists tackling complex formulations.

Interesting facts

Intriguing Facts About Diethyl-[2-[2-(1-Naphthylmethyl)-3-tetrahydrofuran-2-yl-propanoyl]oxyethyl]ammonium;2-Hydroxy-2-Oxo-Acetate

This compound, known for its complex structure, offers several fascinating features from a chemical perspective:

  • Innovative Structure: The compound consists of a diethylammonium group attached to a sophisticated ether-linked tetrahydrofuran moiety. Its structure incorporates aromatic components, such as a naphthyl group, which often contributes to its unique chemical properties.
  • Potential Applications: Compounds with similar functional groups frequently demonstrate interesting biological activities. This specific compound could have potential uses in pharmaceuticals, particularly as a scaffold for drug development.
  • Reactivity: The presence of both a hydroxy and a keto group indicates that the compound might participate in various chemical reactions, including but not limited to esterification and acylation reactions, making it a candidate for synthesis in organic chemistry.
  • Interdisciplinary Interest: The compound bridges the fields of organic chemistry and medicinal chemistry, as the design of compounds with enhanced bioactivity often incorporates molecular features that allow for targeted interactions within biological systems.
  • Synthesis and Characterization: Such complex molecules usually require sophisticated synthetic approaches, often involving multiple steps of reaction and purification. Understanding its synthesis can provide insight into the intricate world of organic synthesis techniques.

As a molecular architect, one can appreciate the elegance behind such sophisticated compounds. The study of diethyl-[2-[2-(1-naphthylmethyl)-3-tetrahydrofuran-2-yl-propanoyl]oxyethyl]ammonium;2-hydroxy-2-oxo-acetate not only reinforces one’s knowledge in chemical structures but also sparks curiosity about its potential impacts in various industries.

Synonyms
diethyl-[2-[2-(naphthalen-1-ylmethyl)-3-(oxolan-2-yl)propanoyl]oxyethyl]azanium;2-hydroxy-2-oxoacetate
5ADB8D9388
Diethyl(2-(2-(1-naphthylmethyl)-3-(tetrahydro-2-furyl)propionyloxy)ethyl)ammonium hydrogen oxalate